| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 6778 |
Name | STAT6 |
Synonym | D12S1644|IL-4-STAT|STAT6B|STAT6C;signal transducer and activator of transcription 6, interleukin-4 induced;STAT6;signal transducer and activator of transcription 6, interleukin-4 induced |
Definition | STAT, interleukin4-induced|signal transducer and activator of transcription 6|transcription factor IL-4 STAT |
Position | 12q13 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Signaling events mediated by TCPTP;PID Curated;200065 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | il 4 signaling pathway;PID BioCarta;100127 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | JAK/STAT signaling pathway;PANTHER;P00038 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | IL12-mediated signaling events;PID Curated;200034 |
Disease | atopy;GAD |
Disease | allergic diseases;GAD |
Disease | Eosinophilia;GAD |
Disease | nut allergy;GAD |
Disease | DRS;GAD |
Disease | IgE levels;GAD |
Disease | minimal change nephrotic syndrome;GAD |
Disease | IMMUNE;GAD |
Disease | endometriosis;GAD |
Disease | REPRODUCTION;GAD |
Disease | eosinophilic esophagitis (pediatric);GAD |
Disease | Graves' disease IgE;GAD |
Disease | dermatitis and eczema;GAD |
Disease | total serum IgE levels;GAD |
Disease | Asthma;GAD |
Disease | Total IgE;GAD |
Disease | Allergic diseases (bronchial asthma. atopic dermatitis and/or food-related anaphylaxis);GAD |
Disease | anaphylaxis, food-related;GAD |
Disease | Eosinophilic esophagitis (pediatric);NHGRI |
Disease | RENAL;GAD |
External Links | |
Links to Entrez Gene | 6778 |
Links to all GeneRIF Items | 6778 |
Links to iHOP | 6778 |
Sequence Information | |
Nucleotide Sequence | >6778 : length: 2544 atgtctctgtggggtctggtctccaagatgcccccagaaaaagtgcagcggctctatgtc gactttccccaacacctgcggcatcttctgggtgactggctggagagccagccctgggag ttcctggtcggctccgacgccttctgctgcaacttggctagtgccctactttcagacact gtccagcaccttcaggcctcggtgggagagcagggggaggggagcaccatcttgcaacac atcagcacccttgagagcatatatcagagggaccccctgaagctggtggccactttcaga caaatacttcaaggagagaaaaaagctgttatggaacagttccgccacttgccaatgcct ttccactggaagcaggaagaactcaagtttaagacaggcttgcggaggctgcagcaccga gtaggggagatccaccttctccgagaagccctgcagaagggggctgaggctggccaagtg tctctgcacagcttgatagaaactcctgctaatgggactgggccaagtgaggccctggcc atgctactgcaggagaccactggagagctagaggcagccaaagccctagtgctgaagagg atccagatttggaaacggcagcagcagctggcagggaatggcgcaccgtttgaggagagc ctggccccactccaggagaggtgtgaaagcctggtggacatttattcccagctacagcag gaggtaggggcggctggtggggagcttgagcccaagacccgggcatcgctgactggccgg ctggatgaagtcctgagaaccctcgtcaccagttgcttcctggtggagaagcagcccccc caggtactgaagactcagaccaagttccaggctggagttcgattcctgttgggcttgagg ttcctgggggccccagccaagcctccgctggtcagggccgacatggtgacagagaagcag gcgcgggagctgagtgtgcctcagggtcctggggctggagcagaaagcactggagaaatc atcaacaacactgtgcccttggagaacagcattcctgggaactgctgctctgccctgttc aagaacctgcttctcaagaagatcaagcggtgtgagcggaagggcactgagtctgtcaca gaggagaagtgcgctgtgctcttctctgccagcttcacacttggccccggcaaactcccc atccagctccaggccctgtctctgcccctggtggtcatcgtccatggcaaccaagacaac aatgccaaagccactatcctgtgggacaatgccttctctgagatggaccgcgtgcccttt gtggtggctgagcgggtgccctgggagaagatgtgtgaaactctgaacctgaagttcatg gctgaggtggggaccaaccgggggctgctcccagagcacttcctcttcctggcccagaag atcttcaatgacaacagcctcagtatggaggccttccagcaccgttctgtgtcctggtcg cagttcaacaaggagatcctgctgggccgtggcttcaccttttggcagtggtttgatggt gtcctggacctcaccaaacgctgtctccggagctactggtctgaccggctgatcattggc ttcatcagcaaacagtacgttactagccttcttctcaatgagcccgacggaacctttctc ctccgcttcagcgactcagagattgggggcatcaccattgcccatgtcatccggggccag gatggctctccacagatagagaacatccagccattctctgccaaagacctgtccattcgc tcactgggggaccgaatccgggatcttgctcagctcaaaaatctctatcccaagaagccc aaggatgaggctttccggagccactacaagcctgaacagatgggtaaggatggcaggggt tatgtcccagctaccatcaagatgaccgtggaaagggaccaaccacttcctaccccagag ctccagatgcctaccatggtgccttcttatgaccttggaatggcccctgattcctccatg agcatgcagcttggcccagatatggtgccccaggtgtacccaccacactctcactccatc cccccgtatcaaggcctctccccagaagaatcagtcaacgtgttgtcagccttccaggag cctcacctgcagatgccccccagcctgggccagatgagcctgccctttgaccagcctcac ccccagggcctgctgccgtgccagcctcaggagcatgctgtgtccagccctgaccccctg ctctgctcagatgtgaccatggtggaagacagctgcctgagccagccagtgacagcgttt cctcagggcacttggattggtgaagacatattccctcctctgctgcctcccactgaacag gacctcactaagcttctcctggaggggcaaggggagtcggggggagggtccttgggggca cagcccctcctgcagccctcccactatgggcaatctgggatctcaatgtcccacatggac ctaagggccaaccccagttggtga |
Protein Sequence | >6778 : length: 847 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD LRANPSW |