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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4915

Name

NTRK2

Synonym

GP145-TrkB|TRKB|trk-B;neurotrophic tyrosine kinase, receptor, type 2;NTRK2;neurotrophic tyrosine kinase, receptor, type 2

Definition

BDNF-tropomyosine receptor kinase B|BDNF/NT-3 growth factors receptor|trkB tyrosine kinase|tyrosine kinase receptor B

Position

9q22.1

Gene Type

protein-coding

Pathways and Diseases

Pathway

Signalling by NGF;Reactome;REACT:11061

Pathway

Neurotrophic factor-mediated Trk receptor signaling;PID Curated;200128

Pathway

MAPK signaling pathway;KEGG PATHWAY;hsa04010

Pathway

Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722

Disease

Cancers of the nervous system;KEGG DISEASE

Disease

Cancers;KEGG DISEASE

Disease

PSYCH;GAD

Disease

bulimia;GAD

Disease

CHEMDEPENDENCY;GAD

Disease

anorexia nervosa;GAD

Disease

Neuroblastoma;KEGG DISEASE;H00043

Disease

nicotine dependence;GAD

Disease

Obesity, hyperphagia, and developmental delay;OMIM

External Links

Links to Entrez Gene

4915

Links to all GeneRIF Items

4915

Links to iHOP

4915

Sequence Information

Nucleotide Sequence

>4915 : length: 1434
atgtcgtcctggataaggtggcatggacccgccatggcgcggctctggggcttctgctgg
ctggttgtgggcttctggagggccgctttcgcctgtcccacgtcctgcaaatgcagtgcc
tctcggatctggtgcagcgacccttctcctggcatcgtggcatttccgagattggagcct
aacagtgtagatcctgagaacatcaccgaaattttcatcgcaaaccagaaaaggttagaa
atcatcaacgaagatgatgttgaagcttatgtgggactgagaaatctgacaattgtggat
tctggattaaaatttgtggctcataaagcatttctgaaaaacagcaacctgcagcacatc
aattttacccgaaacaaactgacgagtttgtctaggaaacatttccgtcaccttgacttg
tctgaactgatcctggtgggcaatccatttacatgctcctgtgacattatgtggatcaag
actctccaagaggctaaatccagtccagacactcaggatttgtactgcctgaatgaaagc
agcaagaatattcccctggcaaacctgcagatacccaattgtggtttgccatctgcaaat
ctggccgcacctaacctcactgtggaggaaggaaagtctatcacattatcctgtagtgtg
gcaggtgatccggttcctaatatgtattgggatgttggtaacctggtttccaaacatatg
aatgaaacaagccacacacagggctccttaaggataactaacatttcatccgatgacagt
gggaagcagatctcttgtgtggcggaaaatcttgtaggagaagatcaagattctgtcaac
ctcactgtgcattttgcaccaactatcacatttctcgaatctccaacctcagaccaccac
tggtgcattccattcactgtgaaaggcaaccccaaaccagcgcttcagtggttctataac
ggggcaatattgaatgagtccaaatacatctgtactaaaatacatgttaccaatcacacg
gagtaccacggctgcctccagctggataatcccactcacatgaacaatggggactacact
ctaatagccaagaatgagtatgggaaggatgagaaacagatttctgctcacttcatgggc
tggcctggaattgacgatggtgcaaacccaaattatcctgatgtaatttatgaagattat
ggaactgcagcgaatgacatcggggacaccacgaacagaagtaatgaaatcccttccaca
gacgtcactgataaaaccggtcgggaacatctctcggtctatgctgtggtggtgattgcg
tctgtggtgggattttgccttttggtaatgctgtttctgcttaagttggcaagacactcc
aagtttggcatgaaaggttttgttttgtttcataagatcccactggatgggtag

Protein Sequence

>4915 : length: 477
MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP
NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI
NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES
SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM
NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH
WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT
LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST
DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGFVLFHKIPLDG



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