| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 3976 |
Name | LIF |
Synonym | CDF|DIA|HILDA;leukemia inhibitory factor (cholinergic differentiation factor);LIF;leukemia inhibitory factor (cholinergic differentiation factor) |
Definition | D factor|MLPLI|cholinergic differentiation factor|differentiation inhibitory activity|differentiation stimulating factor|differentiation-inducing factor|differentiation-stimulating factor|hepatocyte-stimulating factor III|human interleukin in DA cells|leu |
Position | 22q12.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Validated transcriptional targets of AP1 family members Fra1 and Fra2;PID Curated;200044 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Disease | Pre-Eclampsia;FunDO |
Disease | Ischemia;FunDO |
Disease | REPRODUCTION;GAD |
Disease | PSYCH;GAD |
Disease | inflammatory bowel disease (early onset);GAD |
Disease | Dermatitis;FunDO |
Disease | IMMUNE;GAD |
Disease | Ovarian cancer;FunDO |
Disease | schizophrenia;GAD |
Disease | Infertility;FunDO |
Disease | Alopecia;FunDO |
Disease | Infertility, Female;GAD |
Disease | Pancreas cancer;FunDO |
Disease | Endometriosis;FunDO |
Disease | Sella turcica tumor;FunDO |
External Links | |
Links to Entrez Gene | 3976 |
Links to all GeneRIF Items | 3976 |
Links to iHOP | 3976 |
Sequence Information | |
Nucleotide Sequence | >3976 : length: 609 atgaaggtcttggcggcaggagttgtgcccctgctgttggttctgcactggaaacatggg gcggggagccccctccccatcacccctgtcaacgccacctgtgccatacgccacccatgt cacaacaacctcatgaaccagatcaggagccaactggcacagctcaatggcagtgccaat gccctctttattctctattacacagcccagggggagccgttccccaacaacctggacaag ctatgtggccccaacgtgacggacttcccgcccttccacgccaacggcacggagaaggcc aagctggtggagctgtaccgcatagtcgtgtaccttggcacctccctgggcaacatcacc cgggaccagaagatcctcaaccccagtgccctcagcctccacagcaagctcaacgccacc gccgacatcctgcgaggcctccttagcaacgtgctgtgccgcctgtgcagcaagtaccac gtgggccatgtggacgtgacctacggccctgacacctcgggtaaggatgtcttccagaag aagaagctgggctgtcaactcctggggaagtataagcagatcatcgccgtgttggcccag gccttctag |
Protein Sequence | >3976 : length: 202 MKVLAAGVVPLLLVLHWKHGAGSPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSAN ALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNIT RDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQK KKLGCQLLGKYKQIIAVLAQAF |