| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 1385 |
Name | CREB1 |
Synonym | CREB;cAMP responsive element binding protein 1;CREB1;cAMP responsive element binding protein 1 |
Definition | CREB-1|active transcription factor CREB|cAMP-response element-binding protein-1|cAMP-responsive element-binding protein 1|cyclic AMP-responsive element-binding protein 1|transactivator protein |
Position | 2q34 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | transcription regulation by methyltransferase of carm1;PID BioCarta;100220 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | signaling pathway from g-protein families;PID BioCarta;100153 |
Pathway | LKB1 signaling events;PID Curated;200061 |
Pathway | HIF-1-alpha transcription factor network;PID Curated;200172 |
Pathway | VEGFR3 signaling in lymphatic endothelium;PID Curated;200188 |
Pathway | oxidative stress induced gene expression via nrf2;PID BioCarta;100238 |
Pathway | CREB phosphorylation through the activation of CaMKK;PID Reactome;500182 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | PKA-mediated phosphorylation of CREB;PID Reactome;500635 |
Pathway | LPA4-mediated signaling events;PID Curated;200036 |
Pathway | Huntington's disease;KEGG PATHWAY;hsa05016 |
Pathway | Post NMDA receptor activation events;PID Reactome;500176 |
Pathway | AKT phosphorylates targets in the nucleus;PID Reactome;500641 |
Pathway | ATF-2 transcription factor network;PID Curated;200116 |
Pathway | Signaling events regulated by Ret tyrosine kinase;PID Curated;200058 |
Pathway | calcium signaling by hbx of hepatitis b virus;PID BioCarta;100150 |
Pathway | human cytomegalovirus and map kinase pathways;PID BioCarta;100149 |
Pathway | Melanogenesis;KEGG PATHWAY;hsa04916 |
Pathway | Opioid Signalling;Reactome;REACT:15295 |
Pathway | mapkinase signaling pathway;PID BioCarta;100113 |
Pathway | CREB phosphorylation;PID Reactome;500457 |
Pathway | Regulation of nuclear SMAD2/3 signaling;PID Curated;200002 |
Pathway | Nongenotropic Androgen signaling;PID Curated;200145 |
Pathway | Signaling mediated by p38-alpha and p38-beta;PID Curated;200154 |
Pathway | role of erk5 in neuronal survival pathway;PID BioCarta;100171 |
Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Antigen processing and presentation;KEGG PATHWAY;hsa04612 |
Pathway | CREB phosphorylation through the activation of Adenylate Cyclase;PID Reactome;500180 |
Pathway | CREB phophorylation through the activation of Ras;PID Reactome;500177 |
Pathway | p38 mapk signaling pathway;PID BioCarta;100085 |
Pathway | Trk receptor signaling mediated by the MAPK pathway;PID Curated;200182 |
Pathway | hypoxia-inducible factor in the cardivascular system;PID BioCarta;100145 |
Pathway | Prostate cancer;KEGG PATHWAY;hsa05215 |
Pathway | AP-1 transcription factor network;PID Curated;200118 |
Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway;PANTHER;P00026 |
Pathway | melanocyte development and pigmentation pathway;PID BioCarta;100108 |
Pathway | erythropoietin mediated neuroprotection through nf-kb;PID BioCarta;100176 |
Pathway | Trk receptor signaling mediated by PI3K and PLC-gamma;PID Curated;200183 |
Pathway | CREB phosphorylation through the activation of CaMKII;PID Reactome;500181 |
Pathway | Calmodulin induced events;PID Reactome;500634 |
Pathway | transcription factor creb and its extracellular signals;PID BioCarta;100198 |
Pathway | p38 signaling mediated by MAPKAP kinases;PID Curated;200135 |
Pathway | NCAM signaling for neurite out-growth;PID Reactome;500079 |
Pathway | Transcription regulation by bZIP transcription factor;PANTHER;P00055 |
Pathway | ca-calmodulin-dependent protein kinase activation;PID BioCarta;100223 |
Pathway | Vasopressin-regulated water reabsorption;KEGG PATHWAY;hsa04962 |
Pathway | CaMK IV-mediated phosphorylation of CREB;PID Reactome;500637 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | FOXA2 and FOXA3 transcription factor networks;PID Curated;200073 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | repression of pain sensation by the transcriptional regulator dream;PID BioCarta;100186 |
Pathway | inhibition of huntingtons disease neurodegeneration by histone deacetylase inhibitors;PID BioCarta;100140 |
Disease | Histiocytoma, angiomatoid fibrous, somatic;OMIM |
Disease | suicide;GAD |
Disease | PHARMACOGENOMIC;GAD |
External Links | |
Links to Entrez Gene | 1385 |
Links to all GeneRIF Items | 1385 |
Links to iHOP | 1385 |
Sequence Information | |
Nucleotide Sequence | >1385 : length: 984 atgaccatggaatctggagccgagaaccagcagagtggagatgcagctgtaacagaagct gaaaaccaacaaatgacagttcaagcccagccacagattgccacattagcccaggtatct atgccagcagctcatgcaacatcatctgctcccaccgtaactctagtacagctgcccaat gggcagacagttcaagtccatggagtcattcaggcggcccagccatcagttattcagtct ccacaagtccaaacagttcagatttcaactattgcagaaagtgaagattcacaggagtca gtggatagtgtaactgattcccaaaagcgaagggaaattctttcaaggaggccttcctac aggaaaattttgaatgacttatcttctgatgcaccaggagtgccaaggattgaagaagag aagtctgaagaggagacttcagcacctgccatcaccactgtaacggtgccaactccaatt taccaaactagcagtggacagtatattgccattacccagggaggagcaatacagctggct aacaatggtaccgatggggtacagggcctgcaaacattaaccatgaccaatgcagcagcc actcagccgggtactaccattctacagtatgcacagaccactgatggacagcagatctta gtgcccagcaaccaagttgttgttcaagctgcctctggagacgtacaaacataccagatt cgcacagcacccactagcactattgcccctggagttgttatggcatcctccccagcactt cctacacagcctgctgaagaagcagcacgaaagagagaggtccgtctaatgaagaacagg gaagcagctcgagagtgtcgtagaaagaagaaagaatatgtgaaatgtttagaaaacaga gtggcagtgcttgaaaatcaaaacaagacattgattgaggagctaaaagcacttaaggac ctttactgccacaaatcagattaa |
Protein Sequence | >1385 : length: 327 MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPN GQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSY RKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLA NNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQI RTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENR VAVLENQNKTLIEELKALKDLYCHKSD |