Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5595

Name

MAPK3

Synonymous

mitogen-activated protein kinase 3;MAPK3;mitogen-activated protein kinase 3

Definition

MAP kinase isoform p44|MAPK 1|extracellular signal-regulated kinase 1|extracellular signal-related kinase 1|insulin-stimulated MAP2 kinase|microtubule-associated protein 2 kinase

Position

16p11.2

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.480C>T; p.A160A; 16:30118412-30118412

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.37G>A; p.E13K; 16:30123173-30123173

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.719C>G; p.S240C; 16:30117726-30117726

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1018-7A>C; p.?; 16:30116797-30116797

 ovaryother; neoplasmUnknown

c.654C>T; p.N218N; 16:30118053-30118053

 skinmalignant_melanomaSubstitution - coding silent

c.1076G>T; p.R359L; 16:30116732-30116732

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.753G>A; p.L251L; 16:30117692-30117692

 skinmalignant_melanomaSubstitution - coding silent

c.954G>A; p.R318R; 16:30116957-30116957

 skinmalignant_melanomaSubstitution - coding silent

c.996G>C; p.Q332H; 16:30116915-30116915

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.532T>C; p.C178R; 16:30118360-30118360

 skinmalignant_melanomaSubstitution - Missense

c.159C>T; p.Y53Y; 16:30123051-30123051

 central_nervous_system; braingliomaSubstitution - coding silent

c.1007C>A; p.P336Q; 16:30116904-30116904

 skinmalignant_melanomaSubstitution - Missense

c.325G>C; p.A109P; 16:30121852-30121852

 thyroidcarcinoma; medullary_carcinomaSubstitution - Missense

c.533G>A; p.C178Y; 16:30118359-30118359

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1101G>T; p.E367D; 16:30116707-30116707

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.303C>T; p.I101I; 16:30121874-30121874

 skinmalignant_melanomaSubstitution - coding silent

c.632G>A; p.R211Q; 16:30118075-30118075

 bone; extraskeletalEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.1119C>T; p.P373P; 16:30116689-30116689

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1119C>T; p.P373P; 16:30116689-30116689

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.288C>T; p.R96R; 16:30121889-30121889

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.229G>A; p.E77K; 16:30121948-30121948

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.489C>T; p.L163L; 16:30118403-30118403

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.258C>T; p.L86L; 16:30121919-30121919

 skinmalignant_melanomaSubstitution - coding silent

c.1003G>A; p.D335N; 16:30116908-30116908

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.556G>C; p.G186R; 16:30118151-30118151

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.942C>T; p.N314N; 16:30116969-30116969

 skinmalignant_melanomaSubstitution - coding silent

c.952C>T; p.R318W; 16:30116959-30116959

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.908C>T; p.A303V; 16:30117003-30117003

 skinmalignant_melanomaSubstitution - Missense

c.621G>T; p.T207T; 16:30118086-30118086

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.305G>A; p.G102D; 16:30121872-30121872

 skinmalignant_melanomaSubstitution - Missense

c.806T>C; p.L269P; 16:30117255-30117255

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.259C>T; p.R87W; 16:30121918-30121918

 skinmalignant_melanomaSubstitution - Missense

c.1076G>A; p.R359Q; 16:30116732-30116732

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.443A>G; p.Y148C; 16:30118449-30118449

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1011G>A; p.T337T; 16:30116900-30116900

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.511A>G; p.N171D; 16:30118381-30118381

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.52G>C; p.E18Q; 16:30123158-30123158

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.566G>A; p.R189Q; 16:30118141-30118141

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.111C>T; p.D37D; 16:30123099-30123099

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.565C>T; p.R189W; 16:30118142-30118142

 bone; pelvisEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.691G>T; p.V231L; 16:30117754-30117754

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.1075C>T; p.R359W; 16:30116733-30116733

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.426T>C; p.H142H; 16:30118466-30118466

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.426T>C; p.H142H; 16:30118466-30118466

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.555C>T; p.F185F; 16:30118152-30118152

 skinmalignant_melanomaSubstitution - coding silent

c.477C>T; p.S159S; 16:30118415-30118415

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.477C>T; p.S159S; 16:30118415-30118415

 breastcarcinomaSubstitution - coding silent

c.1084G>A; p.E362K; 16:30116724-30116724

 skinmalignant_melanomaSubstitution - Missense

c.545T>A; p.I182N; 16:30118162-30118162

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.567G>T; p.R189R; 16:30118140-30118140

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.454C>T; p.R152W; 16:30118438-30118438

 breastcarcinomaSubstitution - Missense

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