| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5595 |
Name | MAPK3 |
Synonymous | mitogen-activated protein kinase 3;MAPK3;mitogen-activated protein kinase 3 |
Definition | MAP kinase isoform p44|MAPK 1|extracellular signal-regulated kinase 1|extracellular signal-related kinase 1|insulin-stimulated MAP2 kinase|microtubule-associated protein 2 kinase |
Position | 16p11.2 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
MAP2K1 | REACTOME; |
in same component |
NFATC1 | NCI_NATURE; |
in same component |
PRKCD | NCI_NATURE; |
interacts with |
ADRBK1 | HPRD; |
interacts with |
AGTR1 | HPRD; |
interacts with |
ARRB1 | HPRD; |
interacts with |
ARRB2 | BIOGRID; |
interacts with |
ARRB2 | HPRD; |
interacts with |
ATP1A1 | BIOGRID; |
interacts with |
AVPR2 | BIOGRID; |
interacts with |
AVPR2 | HPRD; |
interacts with |
BAZ1B | BIOGRID; |
interacts with |
BCL2 | HPRD; |
interacts with |
BCL3 | HPRD; |
interacts with |
C1QBP | BIOGRID; |
interacts with |
C1QBP | HPRD; |
interacts with |
CASP8 | HPRD; |
interacts with |
CASP8 | MINT; |
interacts with |
CASP9 | CELL_MAP; |
interacts with |
CASP9 | HPRD; |
interacts with |
CAV1 | CELL_MAP; |
interacts with |
CAV1 | HPRD; |
interacts with |
CDC25C | BIOGRID; |
interacts with |
CEBPB | HPRD; |
interacts with |
CIITA | BIOGRID; |
interacts with |
DCC | BIOGRID; |
interacts with |
DCC | HPRD; |
interacts with |
DUSP10 | HPRD; |
interacts with |
DUSP1 | BIOGRID; |
interacts with |
DUSP1 | HPRD; |
interacts with |
DUSP3 | BIOGRID; |
interacts with |
DUSP3 | HPRD; |
interacts with |
DUSP4 | BIOGRID; |
interacts with |
DUSP4 | HPRD; |
interacts with |
DUSP5 | BIOGRID; |
interacts with |
DUSP5 | HPRD; |
interacts with |
DUSP6 | BIOGRID; |
interacts with |
DUSP6 | HPRD; |
interacts with |
ELK1 | BIOGRID; |
interacts with |
ELK1 | CELL_MAP; |
interacts with |
ELK1 | HPRD; |
interacts with |
EPOR | HPRD; |
interacts with |
ESR1 | HPRD; |
interacts with |
ETS1 | HPRD; |
interacts with |
ETV1 | BIOGRID; |
interacts with |
FCGR2B | HPRD; |
interacts with |
GAB1 | HPRD; |
interacts with |
GAB2 | HPRD; |
interacts with |
GAB2 | MINT; |
interacts with |
GATA1 | HPRD; |
interacts with |
GATA4 | HPRD; |
interacts with |
GJA1 | HPRD; |
interacts with |
GMFB | BIOGRID; |
interacts with |
GMFB | HPRD; |
interacts with |
GTF2I | BIOGRID; |
interacts with |
GTF2I | HPRD; |
interacts with |
HDAC4 | BIOGRID; |
interacts with |
HDAC4 | HPRD; |
interacts with |
HIF1A | HPRD; |
interacts with |
HMMR | HPRD; |
interacts with |
HNF4A | BIOGRID; |
interacts with |
HSF1 | HPRD; |
interacts with |
HSF4 | HPRD; |
interacts with |
HSPB8 | HPRD; |
interacts with |
IER3 | BIOGRID; |
interacts with |
IER3 | HPRD; |
interacts with |
INSR | BIOGRID; |
interacts with |
INSR | HPRD; |
interacts with |
JUND | HPRD; |
interacts with |
JUN | BIOGRID; |
interacts with |
JUN | CELL_MAP; |
interacts with |
JUN | HPRD; |
interacts with |
KRT8 | HPRD; |
interacts with |
Ksr1 | MINT; |
interacts with |
KSR2 | HPRD; |
interacts with |
LAMTOR3 | BIOGRID; |
interacts with |
LAMTOR3 | HPRD; |
interacts with |
LCK | HPRD; |
interacts with |
LIPE | HPRD; |
interacts with |
LRPAP1 | HPRD; |
interacts with |
LYN | BIOGRID; |
interacts with |
LYN | HPRD; |
interacts with |
MAP2K1 | BIOGRID; |
interacts with |
MAP2K1 | CELL_MAP; |
interacts with |
MAP2K1 | HPRD; |
interacts with |
MAP2K1 | MINT; |
interacts with |
MAP2K2 | BIOGRID; |
interacts with |
MAP2K2 | CELL_MAP; |
interacts with |
MAP2K2 | HPRD; |
interacts with |
MAP2K3 | BIOGRID; |
interacts with |
MAP2K3 | HPRD; |
interacts with |
MAP3K14 | HPRD; |
interacts with |
MAPK14 | BIOGRID; |
interacts with |
MAPK14 | CELL_MAP; |
interacts with |
MAPK14 | HPRD; |
interacts with |
MAPK1 | HPRD; |
interacts with |
MAPK8 | HPRD; |
interacts with |
MBP | HPRD; |
interacts with |
METAP2 | HPRD; |
interacts with |
MKNK1 | BIOGRID; |
interacts with |
MYC | BIOGRID; |
interacts with |
MYC | HPRD; |
interacts with |
MYLK | HPRD; |
interacts with |
NCKIPSD | HPRD; |
interacts with |
NGFR | HPRD; |
interacts with |
PAK2 | HPRD; |
interacts with |
PDE6G | HPRD; |
interacts with |
PEA15 | BIOGRID; |
interacts with |
PEA15 | HPRD; |
interacts with |
PEBP4 | MINT; |
interacts with |
PLAT | HPRD; |
interacts with |
PLCB1 | HPRD; |
interacts with |
PPARA | HPRD; |
interacts with |
PPP1CA | HPRD; |
interacts with |
PPP2CA | HPRD; |
interacts with |
PRKCD | HPRD; |
interacts with |
PRKCE | HPRD; |
interacts with |
PRKCZ | HPRD; |
interacts with |
PTPN11 | HPRD; |
interacts with |
PTPN5 | BIOGRID; |
interacts with |
Ptpn5 | CELL_MAP; |
interacts with |
PTPN5 | HPRD; |
interacts with |
PTPN7 | BIOGRID; |
interacts with |
PTPN7 | HPRD; |
interacts with |
PTPRR | BIOGRID; |
interacts with |
Ptprr | CELL_MAP; |
interacts with |
PTPRR | HPRD; |
interacts with |
PXN | HPRD; |
interacts with |
RAB4A | HPRD; |
interacts with |
RAF1 | BIOGRID; |
interacts with |
RAF1 | HPRD; |
interacts with |
RAF1 | MINT; |
interacts with |
RCAN1 | HPRD; |
interacts with |
RPS6KA1 | BIOGRID; |
interacts with |
RPS6KA1 | CELL_MAP; |
interacts with |
RPS6KA1 | HPRD; |
interacts with |
RPS6KA2 | BIOGRID; |
interacts with |
Rps6ka3 | BIOGRID; |
interacts with |
RPS6KA3 | BIOGRID; |
interacts with |
Rps6ka3 | CELL_MAP; |
interacts with |
RPS6KA3 | HPRD; |
interacts with |
RPS6KA4 | BIOGRID; |
interacts with |
RPS6KA4 | HPRD; |
interacts with |
Rps6kb1 | BIOGRID; |
interacts with |
RPS6KB1 | HPRD; |
interacts with |
RXRA | BIOGRID; |
interacts with |
SMAD2 | HPRD; |
interacts with |
SNCA | BIOGRID; |
interacts with |
SNCG | BIOGRID; |
interacts with |
SORBS3 | HPRD; |
interacts with |
SP1 | HPRD; |
interacts with |
SPIB | BIOGRID; |
interacts with |
SPIB | HPRD; |
interacts with |
SQSTM1 | MINT; |
interacts with |
SREBF1 | BIOGRID; |
interacts with |
SREBF1 | HPRD; |
interacts with |
SREBF2 | BIOGRID; |
interacts with |
SREBF2 | HPRD; |
interacts with |
STAT3 | HPRD; |
interacts with |
STAT5A | HPRD; |
interacts with |
STMN1 | HPRD; |
interacts with |
STMN2 | HPRD; |
interacts with |
SYK | HPRD; |
interacts with |
SYN1 | HPRD; |
interacts with |
TAL1 | HPRD; |
interacts with |
TAL2 | HPRD; |
interacts with |
TCF3 | HPRD; |
interacts with |
TGIF1 | HPRD; |
interacts with |
TH | BIOGRID; |
interacts with |
TH | HPRD; |
interacts with |
TNFSF11 | HPRD; |
interacts with |
TOP2B | HPRD; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TSC2 | HPRD; |
interacts with |
UBR5 | BIOGRID; |
interacts with |
UBTF | HPRD; |
interacts with |
VDR | BIOGRID; |
interacts with |
ZNF7 | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for MAPK3 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
MAP2K1 | REACTOME; |
reacts with |
MAPK1 | NCI_NATURE; |
reacts with |
MAPK3 | NCI_NATURE; |
reacts with |
MAPK3 | REACTOME; |
reacts with |
NFATC1 | NCI_NATURE; |
reacts with |
PRKCD | NCI_NATURE; |
state change |
IGF1 | NCI_NATURE; |
state change |
MAP2K1 | CELL_MAP; |
state change |
MAP2K1 | NCI_NATURE; |
state change |
MAP2K1 | REACTOME; |
state change |
MAP2K2 | CELL_MAP; |
state change |
MAP2K2 | NCI_NATURE; |
state change |
MAPK3 | REACTOME; |
state change |
Ptpn5 | CELL_MAP; |
state change |
Ptprr | CELL_MAP; |