Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5604

Name

MAP2K1

Synonymous

mitogen-activated protein kinase kinase 1;MAP2K1;mitogen-activated protein kinase kinase 1

Definition

ERK activator kinase 1|MAPK/ERK kinase 1|MAPKK 1|MEK 1|dual specificity mitogen-activated protein kinase kinase 1|protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)

Position

15q22.1-q22.33

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 MAP2K2NCI_NATURE;

in same component

 MAPK3REACTOME;

in same component

 RAF1REACTOME;

in same component

 YWHABREACTOME;

interacts with

 AGTR1HPRD;

interacts with

 ARAFHPRD;

interacts with

 ARRB2HPRD;

interacts with

 BIRC6HPRD;

interacts with

 CASP9HPRD;

interacts with

 CDC37HPRD;

interacts with

 CFLARHPRD;

interacts with

 CPNE1HPRD;

interacts with

 CPNE4HPRD;

interacts with

 EGFRCELL_MAP;

interacts with

 EGFRHPRD;

interacts with

 ELK1HPRD;

interacts with

 EP300HPRD;

interacts with

 EPHB2HPRD;

interacts with

 FlnaBIOGRID;

interacts with

 GRB10BIOGRID;

interacts with

 GRB10HPRD;

interacts with

 HRASBIOGRID;

interacts with

 HRASHPRD;

interacts with

 HSP90AA1HPRD;

interacts with

 HSPA4HPRD;

interacts with

 KSR1HPRD;

interacts with

 Ksr1MINT;

interacts with

 KSR2BIOGRID;

interacts with

 KSR2HPRD;

interacts with

 LAMTOR2BIOGRID;

interacts with

 LAMTOR2HPRD;

interacts with

 LAMTOR3BIOGRID;

interacts with

 LAMTOR3HPRD;

interacts with

 MAP2K2HPRD;

interacts with

 MAP2K7HPRD;

interacts with

 MAP3K1BIOGRID;

interacts with

 MAP3K1MINT;

interacts with

 MAP3K4BIOGRID;

interacts with

 MAP3K4HPRD;

interacts with

 MAP3K8BIOGRID;

interacts with

 MAPK14CELL_MAP;

interacts with

 MAPK14HPRD;

interacts with

 MAPK1BIOGRID;

interacts with

 MAPK1HPRD;

interacts with

 MAPK1MINT;

interacts with

 MAPK3BIOGRID;

interacts with

 MAPK3CELL_MAP;

interacts with

 MAPK3HPRD;

interacts with

 MAPK3MINT;

interacts with

 MAPK8IP3BIOGRID;

interacts with

 MAPK8IP3HPRD;

interacts with

 MYCHPRD;

interacts with

 PAK1HPRD;

interacts with

 PARVAHPRD;

interacts with

 PEBP1BIOGRID;

interacts with

 PEBP1CELL_MAP;

interacts with

 PEBP1HPRD;

interacts with

 PEBP4BIOGRID;

interacts with

 PEBP4HPRD;

interacts with

 PEBP4MINT;

interacts with

 PLK3HPRD;

interacts with

 PRKCIHPRD;

interacts with

 PRKCZHPRD;

interacts with

 RAF1BIOGRID;

interacts with

 RAF1CELL_MAP;

interacts with

 RAF1HPRD;

interacts with

 RAF1MINT;

interacts with

 RPS6KA4HPRD;

interacts with

 TRAF3HPRD;

interacts with

 TRAF6HPRD;

interacts with

 TRIB1HPRD;

interacts with

 VAV1BIOGRID;

interacts with

 WNK1BIOGRID;

interacts with

 WNK1INTACT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 NRASHUMANCYC;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 MAP2K1NCI_NATURE;

reacts with

 MAP2K1REACTOME;

reacts with

 MAP2K2NCI_NATURE;

reacts with

 MAPK3REACTOME;

reacts with

 RAF1REACTOME;

reacts with

 YWHABREACTOME;

state change

 ARAFCELL_MAP;

state change

 EPHB1NCI_NATURE;

state change

 ERBB2NCI_NATURE;

state change

 ERBB3NCI_NATURE;

state change

 GAB1NCI_NATURE;

state change

 IQGAP1NCI_NATURE;

state change

 KSR1NCI_NATURE;

state change

 MAP2K1CELL_MAP;

state change

 MAP2K1REACTOME;

state change

 MAP3K1NCI_NATURE;

state change

 MAP3K8NCI_NATURE;

state change

 MAPK3REACTOME;

state change

 PAK1NCI_NATURE;

state change

 PRKCDNCI_NATURE;

state change

 RAF1NCI_NATURE;

state change

 SHC1NCI_NATURE;

state change

 SHHNCI_NATURE;

state change

 SOS1NCI_NATURE;

state change

 SRCNCI_NATURE;

')