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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5599

Name

MAPK8

Synonymous

mitogen-activated protein kinase 8;MAPK8;mitogen-activated protein kinase 8

Definition

JUN N-terminal kinase|MAP kinase 8|c-Jun N-terminal kinase 1|mitogen-activated protein kinase 8 isoform JNK1 alpha1|mitogen-activated protein kinase 8 isoform JNK1 beta2|stress-activated protein kinase 1|stress-activated protein kinase 1c

Position

10q11.22

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 ARHGEF2NCI_NATURE;

in same component

 DAB1NCI_NATURE;

in same component

 FYNNCI_NATURE;

in same component

 LRP8NCI_NATURE;

in same component

 MAP2K7NCI_NATURE;

in same component

 MAP3K11NCI_NATURE;

in same component

 MAP3K1IMID;

in same component

 MAPK8IP1IMID;

in same component

 NFATC1NCI_NATURE;

in same component

 RARANCI_NATURE;

in same component

 RELNNCI_NATURE;

interacts with

 AKT1HPRD;

interacts with

 ARHGDIABIOGRID;

interacts with

 ATF2BIOGRID;

interacts with

 ATF2HPRD;

interacts with

 BCAR1BIOGRID;

interacts with

 BCL2L11HPRD;

interacts with

 BCL2L1HPRD;

interacts with

 BCL2L1MINT;

interacts with

 BCL2HPRD;

interacts with

 BCL2MINT;

interacts with

 BIDBIOGRID;

interacts with

 BMFHPRD;

interacts with

 CASP10BIOGRID;

interacts with

 CASP8BIOGRID;

interacts with

 CBLMINT;

interacts with

 CDKN1ABIOGRID;

interacts with

 CDKN1AHPRD;

interacts with

 CEBPABIOGRID;

interacts with

 COPS2HPRD;

interacts with

 CRKLMINT;

interacts with

 CRKBIOGRID;

interacts with

 CrkCELL_MAP;

interacts with

 CRKHPRD;

interacts with

 CRKMINT;

interacts with

 DUSP10BIOGRID;

interacts with

 DUSP10HPRD;

interacts with

 DUSP16BIOGRID;

interacts with

 DUSP16HPRD;

interacts with

 DUSP1BIOGRID;

interacts with

 DUSP1HPRD;

interacts with

 Dusp22BIOGRID;

interacts with

 DUSP22BIOGRID;

interacts with

 DUSP22HPRD;

interacts with

 DUSP4BIOGRID;

interacts with

 DUSP4HPRD;

interacts with

 DUSP7HPRD;

interacts with

 EEF2KHPRD;

interacts with

 ELK1BIOGRID;

interacts with

 ELK1HPRD;

interacts with

 ELK3HPRD;

interacts with

 ETV1BIOGRID;

interacts with

 EZRBIOGRID;

interacts with

 FADDBIOGRID;

interacts with

 FASLGBIOGRID;

interacts with

 FASBIOGRID;

interacts with

 FLNBMINT;

interacts with

 GSTP1BIOGRID;

interacts with

 GSTP1HPRD;

interacts with

 H2AFXBIOGRID;

interacts with

 HDAC1BIOGRID;

interacts with

 HDAC9BIOGRID;

interacts with

 HRASHPRD;

interacts with

 HSF1HPRD;

interacts with

 HSF4HPRD;

interacts with

 IKBKAPBIOGRID;

interacts with

 IKBKAPHPRD;

interacts with

 IL27RAHPRD;

interacts with

 IRAK1HPRD;

interacts with

 IRS1BIOGRID;

interacts with

 IRS1HPRD;

interacts with

 JDP2HPRD;

interacts with

 JKAMPHPRD;

interacts with

 JUNBBIOGRID;

interacts with

 JUNBHPRD;

interacts with

 JUNDBIOGRID;

interacts with

 JUNDHPRD;

interacts with

 JUNBIOGRID;

interacts with

 JUNHPRD;

interacts with

 JUNMINT;

interacts with

 KRT8HPRD;

interacts with

 MAP1BHPRD;

interacts with

 MAP2K4BIOGRID;

interacts with

 MAP2K4HPRD;

interacts with

 MAP2K7BIOGRID;

interacts with

 MAP2K7HPRD;

interacts with

 MAP3K1BIOGRID;

interacts with

 MAP3K2BIOGRID;

interacts with

 MAP3K2HPRD;

interacts with

 MAP3K7HPRD;

interacts with

 MAPK14HPRD;

interacts with

 MAPK1HPRD;

interacts with

 MAPK3HPRD;

interacts with

 MAPK8IP1BIOGRID;

interacts with

 MAPK8IP1CELL_MAP;

interacts with

 MAPK8IP1HPRD;

interacts with

 MAPK8IP1MINT;

interacts with

 MAPK8IP2HPRD;

interacts with

 MAPK8IP3BIOGRID;

interacts with

 MAPK8IP3HPRD;

interacts with

 MAPK9HPRD;

interacts with

 MAPKBP1HPRD;

interacts with

 MSNBIOGRID;

interacts with

 MYCBIOGRID;

interacts with

 MYCHPRD;

interacts with

 NFATC2BIOGRID;

interacts with

 NFE2BIOGRID;

interacts with

 NR3C1HPRD;

interacts with

 NR4A1BIOGRID;

interacts with

 PAX2BIOGRID;

interacts with

 PAX2CELL_MAP;

interacts with

 PAX2HPRD;

interacts with

 PDPK1BIOGRID;

interacts with

 PIK3R1HPRD;

interacts with

 PIK3R1MINT;

interacts with

 PPARGHPRD;

interacts with

 PRKD1BIOGRID;

interacts with

 PRKD1HPRD;

interacts with

 PRKDCBIOGRID;

interacts with

 PRKDCHPRD;

interacts with

 PXNHPRD;

interacts with

 RASSF1HPRD;

interacts with

 RELBIOGRID;

interacts with

 RELHPRD;

interacts with

 RHOABIOGRID;

interacts with

 RIPK1HPRD;

interacts with

 Rps6kb1BIOGRID;

interacts with

 RPS6KB1HPRD;

interacts with

 SH3BP5BIOGRID;

interacts with

 SH3BP5HPRD;

interacts with

 SH3RF1HPRD;

interacts with

 SHC1HPRD;

interacts with

 SIRT1BIOGRID;

interacts with

 SMAD2HPRD;

interacts with

 SNCABIOGRID;

interacts with

 SNCGBIOGRID;

interacts with

 SPAG9BIOGRID;

interacts with

 SPAG9HPRD;

interacts with

 SPI1BIOGRID;

interacts with

 SPIBBIOGRID;

interacts with

 SPIBHPRD;

interacts with

 SRCHPRD;

interacts with

 STAT3HPRD;

interacts with

 TFCP2BIOGRID;

interacts with

 TNFRSF10BBIOGRID;

interacts with

 TNFRSF1ABIOGRID;

interacts with

 TNFSF11HPRD;

interacts with

 Tp53BIOGRID;

interacts with

 TP53BIOGRID;

interacts with

 TP53MINT;

interacts with

 TP73HPRD;

interacts with

 TRAF2HPRD;

interacts with

 TRAF6HPRD;

interacts with

 VRK2HPRD;

interacts with

 WWOXHPRD;

interacts with

 WWOXMINT;

interacts with

 XRCC6HPRD;

interacts with

 YWHAZHPRD;

Metabolic Interaction   [Top]

There is no record for MAPK8

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 ARHGEF2NCI_NATURE;

reacts with

 CALM1NCI_NATURE;

reacts with

 DAB1NCI_NATURE;

reacts with

 FYNNCI_NATURE;

reacts with

 LRP8NCI_NATURE;

reacts with

 MAP2K7NCI_NATURE;

reacts with

 MAP3K11NCI_NATURE;

reacts with

 MAP3K1IMID;

reacts with

 MAPK8IP1IMID;

reacts with

 MAPK8IMID;

reacts with

 MAPK8NCI_NATURE;

reacts with

 NFATC1NCI_NATURE;

reacts with

 RARANCI_NATURE;

reacts with

 RELNNCI_NATURE;

state change

 ANGPT1NCI_NATURE;

state change

 BCAR1NCI_NATURE;

state change

 BTKNCI_NATURE;

state change

 CRKNCI_NATURE;

state change

 DOK1NCI_NATURE;

state change

 DSCAMREACTOME;

state change

 DUSP10IMID;

state change

 DUSP1IMID;

state change

 EDN1NCI_NATURE;

state change

 EDNRANCI_NATURE;

state change

 EPONCI_NATURE;

state change

 EPORNCI_NATURE;

state change

 ERBB2NCI_NATURE;

state change

 ERBB3NCI_NATURE;

state change

 GAB1NCI_NATURE;

state change

 GDNFNCI_NATURE;

state change

 GFRA1NCI_NATURE;

state change

 HGFNCI_NATURE;

state change

 KITLGNCI_NATURE;

state change

 KITNCI_NATURE;

state change

 LYNNCI_NATURE;

state change

 MAGED1REACTOME;

state change

 MAP2K4NCI_NATURE;

state change

 MAP2K6NCI_NATURE;

state change

 MAP2K7IMID;

state change

 MAP2K7NCI_NATURE;

state change

 MAP3K1NCI_NATURE;

state change

 METNCI_NATURE;

state change

 NCK1NCI_NATURE;

state change

 NGFREACTOME;

state change

 NGFRREACTOME;

state change

 PAK1REACTOME;

state change

 PRKCBNCI_NATURE;

state change

 PRKCQNCI_NATURE;

state change

 PRKCZNCI_NATURE;

state change

 PTK2BNCI_NATURE;

state change

 RAC1REACTOME;

state change

 RASA1NCI_NATURE;

state change

 S1PR2NCI_NATURE;

state change

 SDC2NCI_NATURE;

state change

 SRCNCI_NATURE;

state change

 TEKNCI_NATURE;

state change

 TRAF6REACTOME;

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