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Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

9146

Name

HGS

Synonymous

hepatocyte growth factor-regulated tyrosine kinase substrate;HGS;hepatocyte growth factor-regulated tyrosine kinase substrate

Definition

human growth factor-regulated tyrosine kinase substrate|protein pp110

Position

17q25

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 AP2B1REACTOME;

in same component

 AP2M1REACTOME;

in same component

 AP2S1REACTOME;

in same component

 CBLREACTOME;

in same component

 EGFREACTOME;

in same component

 EGFRREACTOME;

in same component

 EPN1REACTOME;

in same component

 EPS15REACTOME;

in same component

 EPS15L1REACTOME;

in same component

 SH3GL2REACTOME;

in same component

 SH3KBP1REACTOME;

interacts with

 ABCA1BIOGRID;

interacts with

 ACLYBIOGRID;

interacts with

 AHCYL1BIOGRID;

interacts with

 APCBIOGRID;

interacts with

 APCINTACT;

interacts with

 APLP2BIOGRID;

interacts with

 APPBIOGRID;

interacts with

 ARHGAP20INTACT;

interacts with

 ARL6IP1BIOGRID;

interacts with

 ASAP1INTACT;

interacts with

 ASAP2INTACT;

interacts with

 ATP1A1BIOGRID;

interacts with

 ATP2A2BIOGRID;

interacts with

 BEGAINBIOGRID;

interacts with

 BEGAINHPRD;

interacts with

 BEGAINMINT;

interacts with

 BSGBIOGRID;

interacts with

 C11orf84INTACT;

interacts with

 C1orf190BIOGRID;

interacts with

 C1orf190HPRD;

interacts with

 CASKBIOGRID;

interacts with

 CBLBINTACT;

interacts with

 CBLINTACT;

interacts with

 CBSBIOGRID;

interacts with

 CCDC33BIOGRID;

interacts with

 CCDC33HPRD;

interacts with

 CCDC33MINT;

interacts with

 CD2APINTACT;

interacts with

 CEP55HPRD;

interacts with

 CEP55MINT;

interacts with

 CLTCBIOGRID;

interacts with

 CLTCHPRD;

interacts with

 CRMP1BIOGRID;

interacts with

 CSKINTACT;

interacts with

 CSRP1INTACT;

interacts with

 DAZAP2BIOGRID;

interacts with

 DAZAP2MINT;

interacts with

 DCTN2BIOGRID;

interacts with

 DECR1BIOGRID;

interacts with

 DIAPH1INTACT;

interacts with

 DLG4BIOGRID;

interacts with

 DLG4HPRD;

interacts with

 DNM1INTACT;

interacts with

 DOCK4INTACT;

interacts with

 DOCK5INTACT;

interacts with

 EGFRBIOGRID;

interacts with

 EGFRHPRD;

interacts with

 EGFRINTACT;

interacts with

 EHMT2BIOGRID;

interacts with

 EHMT2HPRD;

interacts with

 EHMT2MINT;

interacts with

 ELMO2INTACT;

interacts with

 EPS15BIOGRID;

interacts with

 EPS15HPRD;

interacts with

 EPS15L1INTACT;

interacts with

 ERRFI1INTACT;

interacts with

 ESRRGBIOGRID;

interacts with

 EXOC7BIOGRID;

interacts with

 EXOC8BIOGRID;

interacts with

 EXOC8HPRD;

interacts with

 EXOC8MINT;

interacts with

 FAM59AINTACT;

interacts with

 FAM59BINTACT;

interacts with

 FAM5CBIOGRID;

interacts with

 FGD6INTACT;

interacts with

 FRS2INTACT;

interacts with

 GAB2INTACT;

interacts with

 GFAPBIOGRID;

interacts with

 GFI1BHPRD;

interacts with

 GFI1BMINT;

interacts with

 GGA1MINT;

interacts with

 GGA2BIOGRID;

interacts with

 GGA2MINT;

interacts with

 GGA3MINT;

interacts with

 GIT1INTACT;

interacts with

 GJA1BIOGRID;

interacts with

 GKAP1BIOGRID;

interacts with

 GKAP1HPRD;

interacts with

 GKAP1MINT;

interacts with

 HAP1BIOGRID;

interacts with

 HAP1HPRD;

interacts with

 HDGFRP3INTACT;

interacts with

 HNRPDLBIOGRID;

interacts with

 HSPA8BIOGRID;

interacts with

 HUNKINTACT;

interacts with

 IGF2BP1INTACT;

interacts with

 IL2RBBIOGRID;

interacts with

 ILKAPBIOGRID;

interacts with

 INPPL1INTACT;

interacts with

 IRS1INTACT;

interacts with

 IRS2INTACT;

interacts with

 IRS4INTACT;

interacts with

 ITCHBIOGRID;

interacts with

 KHDRBS1INTACT;

interacts with

 KRT18BIOGRID;

interacts with

 KRT18HPRD;

interacts with

 KRT18MINT;

interacts with

 KRT19BIOGRID;

interacts with

 KRT19HPRD;

interacts with

 KRT19MINT;

interacts with

 LDOC1BIOGRID;

interacts with

 LDOC1HPRD;

interacts with

 LDOC1MINT;

interacts with

 LYSTBIOGRID;

interacts with

 LYSTHPRD;

interacts with

 MAP3K10BIOGRID;

interacts with

 MAP3K7BIOGRID;

interacts with

 MAP3K7HPRD;

interacts with

 MAP4K5INTACT;

interacts with

 MARK4BIOGRID;

interacts with

 MAT2ABIOGRID;

interacts with

 MED7BIOGRID;

interacts with

 MED7MINT;

interacts with

 MESTBIOGRID;

interacts with

 METHPRD;

interacts with

 MIF4GDBIOGRID;

interacts with

 MIF4GDHPRD;

interacts with

 MIF4GDMINT;

interacts with

 MTHFD1LBIOGRID;

interacts with

 MYCBPINTACT;

interacts with

 NCKAP1INTACT;

interacts with

 NEDD4BIOGRID;

interacts with

 NEDD4HPRD;

interacts with

 NEDD4MINT;

interacts with

 NEDD8BIOGRID;

interacts with

 NF2BIOGRID;

interacts with

 NF2HPRD;

interacts with

 NISCHINTACT;

interacts with

 NMIBIOGRID;

interacts with

 NMIHPRD;

interacts with

 OCLNBIOGRID;

interacts with

 ODR4INTACT;

interacts with

 OSBPL5BIOGRID;

interacts with

 PAK1BIOGRID;

interacts with

 PAK1HPRD;

interacts with

 PEAK1INTACT;

interacts with

 PELP1HPRD;

interacts with

 PFKMBIOGRID;

interacts with

 PIK3AP1INTACT;

interacts with

 PIK3C2BINTACT;

interacts with

 PIK3CAINTACT;

interacts with

 PIK3CBINTACT;

interacts with

 PIK3R1HPRD;

interacts with

 PIK3R1INTACT;

interacts with

 PIK3R2INTACT;

interacts with

 PIK3R3INTACT;

interacts with

 PLD3BIOGRID;

interacts with

 PPM1BINTACT;

interacts with

 PPP1CAINTACT;

interacts with

 PPP1R16ABIOGRID;

interacts with

 PPP1R7BIOGRID;

interacts with

 PPP5CINTACT;

interacts with

 PSTPIP2INTACT;

interacts with

 PTCD3BIOGRID;

interacts with

 PTPLAD1INTACT;

interacts with

 PTPN11INTACT;

interacts with

 PTPN12INTACT;

interacts with

 RAB11AMINT;

interacts with

 RAB14MINT;

interacts with

 RAB4AMINT;

interacts with

 RAB7AMINT;

interacts with

 RADILINTACT;

interacts with

 RHOBTB3BIOGRID;

interacts with

 RSU1BIOGRID;

interacts with

 SCAMP3BIOGRID;

interacts with

 SCAMP3HPRD;

interacts with

 SCRN1BIOGRID;

interacts with

 SF3B3BIOGRID;

interacts with

 SH2D5INTACT;

interacts with

 SH3PXD2AINTACT;

interacts with

 SH3PXD2BINTACT;

interacts with

 SHC1INTACT;

interacts with

 SIRPAINTACT;

interacts with

 SLAIN2INTACT;

interacts with

 SLC25A13INTACT;

interacts with

 SLC25A5INTACT;

interacts with

 SLC25A6INTACT;

interacts with

 SMAD2HPRD;

interacts with

 SNX1BIOGRID;

interacts with

 SNX1HPRD;

interacts with

 SOS1INTACT;

interacts with

 SOS2INTACT;

interacts with

 STAM2BIOGRID;

interacts with

 STAM2HPRD;

interacts with

 STAM2MINT;

interacts with

 STAMBPINTACT;

interacts with

 STAMBIOGRID;

interacts with

 STAMHPRD;

interacts with

 STAMMINT;

interacts with

 STX12HPRD;

interacts with

 SUN2BIOGRID;

interacts with

 SYNJ1INTACT;

interacts with

 TADA2ABIOGRID;

interacts with

 TADA2AHPRD;

interacts with

 TADA2AMINT;

interacts with

 TECINTACT;

interacts with

 TIMMDC1BIOGRID;

interacts with

 TJP2BIOGRID;

interacts with

 TMCC2BIOGRID;

interacts with

 TOM1MINT;

interacts with

 TOM1L1HPRD;

interacts with

 TOM1L1MINT;

interacts with

 TRAP1BIOGRID;

interacts with

 TSG101BIOGRID;

interacts with

 TSG101HPRD;

interacts with

 TSG101INTACT;

interacts with

 TSG101MINT;

interacts with

 TTYH2INTACT;

interacts with

 TUBB2ABIOGRID;

interacts with

 TUBBBIOGRID;

interacts with

 UBA1BIOGRID;

interacts with

 UBE2IBIOGRID;

interacts with

 UBE2IHPRD;

interacts with

 UBQLN1BIOGRID;

interacts with

 UBQLN1HPRD;

interacts with

 UBQLN1MINT;

interacts with

 UBQLN4HPRD;

interacts with

 UBQLN4MINT;

interacts with

 USHBP1BIOGRID;

interacts with

 USHBP1HPRD;

interacts with

 VAMP2HPRD;

interacts with

 VAV3INTACT;

interacts with

 VMP1BIOGRID;

interacts with

 VPS37AHPRD;

interacts with

 VPS37CBIOGRID;

interacts with

 VPS37CHPRD;

interacts with

 VPS37DHPRD;

interacts with

 VPS4ABIOGRID;

interacts with

 WASLINTACT;

interacts with

 WDR44INTACT;

interacts with

 WDR6INTACT;

interacts with

 WDR77INTACT;

interacts with

 WIPF1INTACT;

interacts with

 WIPF2INTACT;

interacts with

 WIPF3INTACT;

interacts with

 YWHABINTACT;

interacts with

 YWHAEINTACT;

interacts with

 YWHAGINTACT;

interacts with

 YWHAHINTACT;

interacts with

 YWHAQINTACT;

interacts with

 YWHAZINTACT;

interacts with

 ZNF302BIOGRID;

Metabolic Interaction   [Top]

There is no record for HGS

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 AP2B1REACTOME;

reacts with

 AP2M1REACTOME;

reacts with

 AP2S1REACTOME;

reacts with

 CBLREACTOME;

reacts with

 EGFREACTOME;

reacts with

 EGFRREACTOME;

reacts with

 EPN1REACTOME;

reacts with

 EPS15REACTOME;

reacts with

 EPS15L1REACTOME;

reacts with

 HGSREACTOME;

reacts with

 SH3GL2REACTOME;

reacts with

 SH3KBP1REACTOME;

reacts with

 VPS28REACTOME;

reacts with

 VPS37AREACTOME;

reacts with

 VPS37BREACTOME;

reacts with

 VPS37CREACTOME;

reacts with

 VPS37DREACTOME;

state change

 CBLREACTOME;

state change

 EGFREACTOME;

state change

 EGFRREACTOME;

state change

 EPN1REACTOME;

state change

 EPS15REACTOME;

state change

 EPS15L1REACTOME;

state change

 HGSREACTOME;

state change

 ITCHNCI_NATURE;

state change

 SH3GL2REACTOME;

state change

 SH3KBP1REACTOME;

state change

 SRCNCI_NATURE;