| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9146 |
Name | HGS |
Synonym | HRS;hepatocyte growth factor-regulated tyrosine kinase substrate;HGS;hepatocyte growth factor-regulated tyrosine kinase substrate |
Definition | human growth factor-regulated tyrosine kinase substrate|protein pp110 |
Position | 17q25 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Signaling by EGFR;Reactome;REACT:9417 |
Pathway | Internalization of ErbB1;PID Curated;200146 |
Pathway | CXCR4-mediated signaling events;PID Curated;200083 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | Phagosome;KEGG PATHWAY;hsa04145 |
Disease | Drug abuse;FunDO |
Disease | Neurilemmoma;FunDO |
Disease | Sella turcica tumor;FunDO |
Disease | Adenoma;FunDO |
External Links | |
Links to Entrez Gene | 9146 |
Links to all GeneRIF Items | 9146 |
Links to iHOP | 9146 |
Sequence Information | |
Nucleotide Sequence | >9146 : length: 2986 CCTCGCGGCTCTAGGGCCGGCGCGGTGACGTGCGCGTGCGCGCACTGGAGGGAAAAGGCG GAAGCGGAAGTCGGGGGGCGCGCCAGCTCGTAGCAGGGGAGCGCCCGCGGCGTCGGGTTT GGGCTGGAGGTCGCCATGGGGCGAGGCAGCGGCACCTTCGAGCGTCTCCTAGACAAGGCG ACCAGCCAGCTCCTGTTGGAGACAGATTGGGAGTCCATTTTGCAGATCTGCGACCTGATC CGCCAAGGGGACACACAAGCAAAATATGCTGTGAATTCCATCAAGAAGAAAGTCAACGAC AAGAACCCACACGTCGCCTTGTATGCCCTGGAGGTCATGGAATCTGTGGTAAAGAACTGT GGCCAGACAGTTCATGATGAGGTGGCCAACAAGCAGACCATGGAGGAGCTGAAGGACCTG CTGAAGAGACAAGTGGAGGTAAACGTCCGTAACAAGATCCTGTACCTGATCCAGGCCTGG GCGCATGCCTTCCGGAACGAGCCCAAGTACAAGGTGGTCCAGGACACCTACCAGATCATG AAGGTGGAGGGGCACGTCTTTCCAGAATTCAAAGAGAGCGATGCCATGTTTGCTGCCGAG AGAGCCCCAGACTGGGTGGACGCTGAGGAATGCCACCGCTGCAGGGTGCAGTTCGGGGTG ATGACCCGTAAGCACCACTGCCGGGCGTGTGGGCAGATATTCTGTGGAAAGTGTTCTTCC AAGTACTCCACCATCCCCAAGTTTGGCATCGAGAAGGAGGTGCGCGTGTGTGAGCCCTGC TACGAGCAGCTGAACAGGAAAGCGGAGGGAAAGGCCACTTCCACCACTGAGCTGCCCCCC GAGTACCTGACCAGCCCCCTGTCTCAGCAGTCCCAGCTGCCCCCCAAGAGGGACGAGACG GCCCTGCAGGAGGAGGAGGAGCTGCAGCTGGCCCTGGCGCTGTCACAGTCAGAGGCGGAG GAGAAGGAGAGGCTGAGACAGAAGTCCACGTACACTTCGTACCCCAAGGCGGAGCCCATG CCCTCGGCCTCCTCAGCGCCCCCCGCCAGCAGCCTGTACTCTTCACCTGTGAACTCGTCG GCGCCTCTGGCTGAGGACATCGACCCTGAGCTCGCACGGTATCTCAACCGGAACTACTGG GAGAAGAAGCAGGAGGAGGCTCGCAAGAGCCCCACGCCATCTGCGCCCGTGCCCCTGACG GAGCCGGCTGCACAGCCTGGGGAAGGGCACGCAGCCCCCACCAACGTGGTGGAGAACCCC CTCCCGGAGACAGACTCTCAGCCCATTCCTCCCTCTGGTGGCCCCTTTAGTGAGCCACAG TTCCACAATGGCGAGTCTGAGGAGAGCCACGAGCAGTTCCTGAAGGCGCTGCAGAACGCC GTCACCACCTTCGTGAACCGCATGAAGAGTAACCACATGCGGGGCCGCAGCATCACCAAT GACTCGGCCGTGCTCTCACTCTTCCAGTCCATCAACGGCATGCACCCGCAGCTGCTGGAG CTGCTCAACCAGCTGGACGAGCGCAGGCTGTACTATGAGGGGCTGCAGGACAAGCTGGCA CAGATCCGCGATGCCCGGGGGGCGCTGAGTGCCCTGCGCGAAGAGCACCGGGAGAAGCTT CGCCGGGCAGCCGAGGAGGCAGAGCGCCAGCGCCAGATCCAGCTGGCCCAGAAGCTGGAG ATAATGCGGCAGAAGAAGCAGGAGTACCTGGAGGTGCAGAGGCAGCTGGCCATCCAGCGC CTGCAGGAGCAGGAGAAGGAGCGGCAGATGCGGCTGGAGCAGCAGAAGCAGACGGTCCAG ATGCGCGCGCAGATGCCCGCCTTCCCCCTGCCCTACGCCCAGCTCCAGGCCATGCCCGCA GCCGGAGGTGTGCTCTACCAGCCCTCGGGACCAGCCAGCTTCCCCAGCACCTTCAGCCCT GCCGGCTCGGTGGAGGGCTCCCCAATGCACGGCGTGTACATGAGCCAGCCGGCCCCTGCC GCTGGCCCCTACCCCAGCATGCCCAGCACTGCGGCTGATCCCAGCATGGTGAGTGCCTAC ATGTACCCAGCAGGGGCCACTGGGGCGCAGGCGGCCCCCCAGGCCCAGGCCGGACCCACC GCCAGCCCCGCTTACTCATCCTACCAGCCTACTCCCACAGCGGGCTACCAGAACGTGGCC TCCCAGGCCCCACAGAGCCTCCCGGCCATCTCTCAGCCTCCGCAGTCCAGCACCATGGGC TACATGGGGAGCCAGTCAGTCTCCATGGGCTACCAGCCTTACAACATGCAGAATCTCATG ACCACCCTCCCAAGCCAGGATGCGTCTCTGCCACCCCAGCAGCCCTACATCGCGGGGCAG CAGCCCATGTACCAGCAGATGGCACCCTCTGGCGGTCCCCCCCAGCAGCAGCCCCCCGTG GCCCAGCAACCGCAGGCACAGGGGCCGCCGGCACAGGGCAGCGAGGCCCAGCTCATTTCA TTCGACTGACCCAGGCCATGCTCACGTCCGGAGTAACACTACATACAGTTCACCTGAAAC GCCTCGTCTCTAACTGCCGTCGTCCTGCCTCCCTGTCCTCTACTGCCGGTAGTGTCCCTT CTCTGCGAGTGAGGGGGGGCCTTCACCCCAAGCCCACCTCCCTTGTCCTCAGCCTACTGC AGTCCCTGAGTTAGTCTCTGCTTTCTTTCCCCAGGGCTGGGCCATGGGGAGGGAAGGACT TTCTCCCAGGGGAAGCCCCCAGCCCTGTGGGTCATGGTCTGTGAGAGGTGGCAGGAATGG GGACCCTCACCCCCCAAGCAGCCTGTGCCCTCTGGCCGCACTGTGAGCTGGCTGTGGTGT CTGGGTGTGGCCTGGGGCTCCCTCTGCAGGGGCCTCTCTCGGCAGCCACAGCCAAGGGTG GAGGCTTCAGGTCTCCAGCTTCTCTGCTTCTCAGCTGCCATCTCCAGTGCCCCAGAATGG TACAGCGATAATAAAATGTATTTCAGAAAGCAAAAAAAAAAAAAAA |
Protein Sequence | >9146 : length: 777 MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHV ALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFR NEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKH HCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTS PLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASS APPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQ PGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFV NRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDA RGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQE KERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVE GSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAY SSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPS QDASLPPQQPYIAGQQPMYQQGETHTRGPFSADRTRTQVSGQIRASASVDRKNREFT |