| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4296 |
Name | MAP3K11 |
Synonym | MEKK11|MLK-3|MLK3|PTK1|SPRK;mitogen-activated protein kinase kinase kinase 11;MAP3K11;mitogen-activated protein kinase kinase kinase 11 |
Definition | SH3 domain-containing proline-rich kinase|mixed lineage kinase 3|protein-tyrosine kinase PTK1|src-homology 3 domain-containing proline-rich kinase |
Position | 11q13.1-q13.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | CDC42 signaling events;PID Curated;200057 |
Pathway | mapkinase signaling pathway;PID BioCarta;100113 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Reelin signaling pathway;PID Curated;200051 |
Pathway | RAC1 signaling pathway;PID Curated;200190 |
Pathway | IFN-gamma pathway;PID Curated;200110 |
External Links | |
Links to Entrez Gene | 4296 |
Links to all GeneRIF Items | 4296 |
Links to iHOP | 4296 |
Sequence Information | |
Nucleotide Sequence | >4296 : length: 3712 ATCTGATGCTGTTTCCTGCAGGAGGGAGAAGAGCGGAAAAAAGTGAAACTCCACCCTCCA CCTCTGCCTCCCGCCCCCGGGGCCAAAGTACAAAGGGAGGAGGAAGAAGGGAGCGGGGTC GGAGCCGTCGGGGCCAAAGGAGACGGGGCCAGGAACAGGCAGTCTCGGCCCAACTGCGGA CGCTCCCTCCACCCCCTGCGCAAAAAGACCCAACCGGAGTTGAGGCGCTGCCCCTGAAGG CCCCACCTTACACTTGGCGGGGGCCGGAGCCAGGCTCCCAGGACTGCTCCAGAACCGAGG GAAGCTCGGGTCCCTCCAAGCTAGCCATGGTGAGGCGCCGGAGGCCCCGGGGCCCCACCC CCCCGGCCTGACCACACTGCCCTGGGTGCCCTCCTCCAGAAGCCCGAGATGCGGGGGGCC GGGAGACAACACTCCTGGCTCCCCAGAGAGGCGTGGGTCTGGGGCTGAGGGCCAGGGCCC GGATGCCCAGGTTCCGGGACTAGGGCCTTGGCAGCCAGCGGGGGTGGGGACCACGGGCAC CCAGAGAAGGTCCTCCACACATCCCAGCGCCGGCTCCCGGCCATGGAGCCCTTGAAGAGC CTCTTCCTCAAGAGCCCTCTAGGGTCATGGAATGGCAGTGGCAGCGGGGGTGGTGGGGGC GGTGGAGGAGGCCGGCCTGAGGGGTCTCCAAAGGCAGCGGGTTATGCCAACCCGGTGTGG ACAGCCCTGTTCGACTACGAGCCCAGTGGGCAGGATGAGCTGGCCCTGAGGAAGGGTGAC CGTGTGGAGGTGCTGTCCCGGGACGCAGCCATCTCAGGAGACGAGGGCTGGTGGGCGGGC CAGGTGGGTGGCCAGGTGGGCATCTTCCCGTCCAACTATGTGTCTCGGGGTGGCGGCCCG CCCCCCTGCGAGGTGGCCAGCTTCCAGGAGCTGCGGCTGGAGGAGGTGATCGGCATTGGA GGCTTTGGCAAGGTGTACAGGGGCAGCTGGCGAGGTGAGCTGGTGGCTGTGAAGGCAGCT CGCCAGGACCCCGATGAGGACATCAGTGTGACAGCCGAGAGCGTTCGCCAGGAGGCCCGG CTCTTCGCCATGCTGGCACACCCCAACATCATTGCCCTCAAGGCTGTGTGCCTGGAGGAG CCCAACCTGTGCCTGGTGATGGAGTATGCAGCCGGTGGGCCCCTCAGCCGAGCTCTGGCC GGGCGGCGCGTGCCTCCCCATGTGCTGGTCAACTGGGCTGTGCAGATTGCCCGTGGGATG CACTACCTGCACTGCGAGGCCCTGGTGCCCGTCATCCACCGTGATCTCAAGTCCAACAAC ATTTTGCTGCTGCAGCCCATTGAGAGTGACGACATGGAGCACAAGACCCTGAAGATCACC GACTTTGGCCTGGCCCGAGAGTGGCACAAAACCACACAAATGAGTGCCGCGGGCACCTAC GCCTGGATGGCTCCTGAGGTTATCAAGGCCTCCACCTTCTCTAAGGGCAGTGACGTCTGG AGTTTTGGGGTGCTGCTGTGGGAACTGCTGACCGGGGAGGTGCCATACCGTGGCATTGAC TGCCTTGCTGTGGCCTATGGCGTAGCTGTTAACAAGCTCACACTGCCCATCCCATCCACC TGCCCCGAGCCCTTCGCACAGCTTATGGCCGACTGCTGGGCGCAGGACCCCCACCGCAGG CCCGACTTCGCCTCCATCCTGCAGCAGTTGGAGGCGCTGGAGGCACAGGTCCTACGGGAA ATGCCGCGGGACTCCTTCCATTCCATGCAGGAAGGCTGGAAGCGCGAGATCCAGGGTCTC TTCGACGAGCTGCGAGCCAAGGAAAAGGAACTACTGAGCCGCGAGGAGGAGCTGACGCGA GCGGCGCGCGAGCAGCGGTCACAGGCGGAGCAGCTGCGGCGGCGCGAGCACCTGCTGGCC CAGTGGGAGCTAGAGGTGTTCGAGCGCGAGCTGACGCTGCTGCTGCAGCAGGTGGACCGC GAGCGACCGCACGTGCGCCGCCGCCGCGGGACATTCAAGCGCAGCAAGCTCCGGGCGCGC GACGGCGGCGAGCGTATCAGCATGCCACTCGACTTCAAGCACCGCATCACCGTGCAGGCC TCACCCGGCCTTGACCGGAGGAGAAACGTCTTCGAGGTCGGGCCTGGGGATTCGCCCACC TTTCCCCGGTTCCGAGCCATCCAGTTGGAGCCTGCAGAGCCAGGCCAGGCATGGGGCCGC CAGTCCCCCCGACGTCTGGAGGACTCAAGCAATGGAGAGCGGCGAGCATGCTGGGCTTGG GGTCCCAGTTCCCCCAAGCCTGGGGAAGCCCAGAATGGGAGGAGAAGGTCCCGCATGGAC GAAGCCACATGGTACCTGGATTCAGATGACTCATCCCCCTTAGGATCTCCTTCCACACCC CCAGCACTCAATGAGACTAGGAAACCAAGGCTGAGACAAGACAGAGCCGATCCTGGAACC CAGGTAACCCCCCGCGGCCTAGCCTGGAGCCCGAGGAGCCCAAGAGGCCTGTCCCCGCAG AGCGCGGTAGCAGCTCTGGGACGCCCAAGCTGATCCAGCGGGCGCTGCTGCGCGGCACCG CCCTGCTCGCCTCGCTGGGCCTTGGCCGCGACCTGCAGCCGCCGGGAGGCCCAGGACGCG AGCGCGGGGAGTCCCCGACAACACCCCCCACGCCAACGCCCGCGCCCTGCCCGACCGAGC CGCCCCCTTCCCCGCTCATCTGCTTCTCGCTCAAGACGCCCGACTCCCCGCCCACTCCTG CACCCCTGTTGCTGGACCTGGGTATCCCTGTGGGCCAGCGGTCAGCCAAGAGCCCCCGAC GTGAGGAGGAGCCCCGCGGAGGCACTGTCTCACCCCCACCGGGGACATCACGCTCTGCTC CTGGCACCCCAGGCACCCCACGTTCACCACCCCTGGGCCTCATCAGCCGACCTCGGCCCT CGCCCCTTCGCAGCCGCATTGATCCCTGGAGCTTTGTGTCAGCTGGGCCACGGCCTTCTC CCCTGCCATCACCACAGCCTGCACCCCGCCGAGCACCCTGGACCTTGTTCCCGGACTCAG ACCCCTTCTGGGACTCCCCACCTGCCAACCCCTTCCAGGGGGGCCCCCAGGACTGCAGGG CACAGACCAAAGACATGGGTGCCCAGGCCCCGTGGGTGCCGGAAGCGGGGCCTTGAGTGG GCCAGGCCACTCCCCCGAGCTCCAGCTGCCTTAGGAGGAGTCACAGCATACACTGGAACA GGAGCTGGGTCAGCCTCTGCAGCTGCCTCAGTTTCCCCAGGGACCCCACCCCCCTTTGGG GGTCAGGAACACTACACTGCACAGGAAGCCTTCACACTGGAAGGGGGACCTGCGCCCCCA CATCTGAAACCTGTAGGTCCCCCCAGCTCACCTGCCCTACTGGGGCCCAACACTGTACCC AGCTGGTTGGGAGGACCAGAGCCTGTCTCAGGGAATTGCCTGCTGGGGTGATGCAGGGAG GAGGGGAGGTGCAGGGAAGAGGGGCCGGCCTCAGCTGTCACCAGCACTTTTGACCAAGTC CTGCTACTGCGGCCCCTGCCCTAGGGCTTAGAGCATGGACCTCCTGCCCTGGGGGTCATC TGGGGCCAGGGCTCTCTGGATGCCTTCCTGCTGCCCCAGCCAGGGTTGGAGTCTTAGCCT CGGGATCCAGTGAAGCCAGAAGCCAAATAAACTCAAAAGCTGTCTCCCCACA |
Protein Sequence | >4296 : length: 847 MEPLKSLFLKSPLGSWNGSGSGGGGGGGGGRPEGSPKAAGYANPVWTALFDYEPSGQDEL ALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSRGGGPPPCEVASFQELRLE EVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALK AVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHR DLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVIKASTFS KGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWA QDPHRRPDFASILQQLEALEAQVLREMPRDSFHSMQEGWKREIQGLFDELRAKEKELLSR EEELTRAAREQRSQAEQLRRREHLLAQWELEVFERELTLLLQQVDRERPHVRRRRGTFKR SKLRARDGGERISMPLDFKHRITVQASPGLDRRRNVFEVGPGDSPTFPRFRAIQLEPAEP GQAWGRQSPRRLEDSSNGERRACWAWGPSSPKPGEAQNGRRRSRMDEATWYLDSDDSSPL GSPSTPPALNGNPPRPSLEPEEPKRPVPAERGSSSGTPKLIQRALLRGTALLASLGLGRD LQPPGGPGRERGESPTTPPTPTPAPCPTEPPPSPLICFSLKTPDSPPTPAPLLLDLGIPV GQRSAKSPRREEEPRGGTVSPPPGTSRSAPGTPGTPRSPPLGLISRPRPSPLRSRIDPWS FVSAGPRPSPLPSPQPAPRRAPWTLFPDSDPFWDSPPANPFQGGPQDCRAQTKDMGAQAP WVPEAGP |