Links to all GeneRIF Items | 3486 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 12011225 (IGFBP3) | Insulin-like growth factor I, IGF-binding protein 3, and lung cancer risk in a prospective study of men in China. |
| 12068000 (IGFBP3) | Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer. |
| 12473575 (IGFBP3) | Hypermethylation of IGFBP-3 promoter is associated with non-small cell lung cancer |
| 18450319 (IGFBP3) | IGFBP-3 promoter polymorphisms of -1590 C>A and -202 A>C might be a genetic risk factor for lung cancer |
| 21254935 (IGFBP3) | The A/A genotype and A allele of the IGFBP-3 promoter -1590 site may represent a genetic risk factor for nonsmall cell lung cancer in a Chinese Han population. |
| 21447628 (IGFBP3) | IGFBP-3 positively and negatively impacts on IGF1-induced lung cancer development. |
| 22347413 (IGFBP3) | Heavy smokers carrying susceptible IGF1, IGF2, and IGFBP3 polymorphisms have a higher risk of lung cancer. |
| 23185474 (IGFBP3) | inverse association was shown between IGFBP-3 and lung cancer in case-control studies; circulating level of IGFBP-3 underwent a decline during tumorogenesis and development of lung cancer, suggesting IGFBP-3 a promising candidate for the biomarker of lung cancer[meta-analysis] |
| 23498137 (IGFBP3) | These results suggest that NNK inhibits IGFBP-3 expression to abrogate anti-tumor actions of the IGFBP-3/IGFBP-3R system in smoking-induced lung cancer. |
| 25482372 (IGFBP3) | The unmethylated IGFBP-3 promoter is associated with resistance to radiotherapy in patients with non-small cell lung cancer. |
| 27071409 (IGFBP3) | Independent of obesity, high insulin levels but reduced levels of IGFBP-3 were associated with increased lung cancer risk in current smokers. |
| 28330997 (IGFBP3) | These findings reveal that IGFBP3 is effective in lung cancer cells with high IGF1 signaling activity and imply that relevant biomarkers are essential in selecting lung cancer patients for IGF1-targeted therapy |
| 31085806 (IGFBP3) | Data provide evidence that up-regulation of IGFBP3 might mediate brain metastasis in lung adenocarcinoma. |
| 31366504 (IGFBP3) | we aimed to evaluate serum levels of IGF-1, IGF-2 and IGF-binding protein 3 (IGF-BP3) before and after standard treatment in patients with advanced non-small cell lung cancer (NSCLC) and their prognostic and predictive correlations. |
| 33436560 (IGFBP3) | circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity. |
| 28330997 (Igfbp3) | Igfbp3-null mouse model was generated in combination with Kras(G12D) to compare the tumor burden. Then, IGF-dependent signaling was assessed after expressing wild-type or a mutant IGFBP3 without IGF binding capacity in non-small cell lung cancer (NSCLC) cells |