| General announcement |
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| All files are free to academic researchers world wide and not for profit purposes. All downloadable files are Tab separated text files. The headline of each file provides information for each column. |
Data source |
| The lung cancer-implicated gene collection was mainly based on the GeneRIF (Gene Reference Into Func-tion) and PubMed databases. We performed a keyword-based query against GeneRIF and PubMed database to extract relevant sentences using the expression: [(lung OR pulmonary) AND (cancer OR tumor OR tumour OR carcinoma)]. Further literature curation was performed by clustering abstracts, extracting matched cancer subtypes, collecting species information, and formalizing gene symbols. We consolidated 2,507 human genes, 2,267 protein-coding and 240 non-coding genes. | All homologs of the 2507 human lung cancer genes: |
| The flat file for human lung cancer genes here . |
| The flat file for homologs of lung cancer in other animals here . |
All the pre-computed CRISPR knock-out information is based on Cell Model Passports data: |
| The flat file for all the genes with CRISPR knock-out information here . |
| The flat file for the 43 lung cancer related cell line information. |
All the pre-computed results are based on The Cancer Genome Atlas Lung Adenocarcinoma (TCGA-LUAD) data: |
| The flat file for all the differential expression events here. |
| The flat file for all the co-expressed protein-coding genes and all the co-expressed long non-coding RNAs. |
All the pre-computed results based on The Cancer Genome Atlas Lung Squamous Cell Carcinoma (TCGA-LUSC) data: |
| The flat file for all the differential expression events here. |
| The flat file for all the co-expressed protein-coding genes and all the co-expressed long non-coding RNAs. |
When using this resource, please cite: |
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Yining Liu, Min Zhao. LCGene: an online database for Lung Cancer-implicated Genes and Literature to explore the subtype-specific mechanisms. |