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Cancer metastasis database

Annotation category 5

Expression and regulation

Regulation From TransFac database

IGF-2(h) + IGFBP-3(h) <==> IGF-2(h):IGFBP-3(h) (binding)
IGF-1(h) + IGFBP-3(h) <==> IGF-1(h):IGFBP-3(h) (binding)
IGFBP-3(h) + VDR(h) <==> IGFBP-3(h):VDR(h) (binding)
IGFBP-3(h) --kallikrein-2(h)--> IGFBP3-p14(h) + protein remnants (cleavage)
IGFBP-3(h) --kallikrein-2(h)--> IGFBP3-p24(h) + protein remnants (cleavage)
IGFBP-3(h) --kallikrein-2(h)--> IGFBP3-p20(h) + protein remnants (cleavage)
IGFBP-3(h) --kallikrein-2(h)--> IGFBP3-p18(h) + protein remnants (cleavage)
IGFBP-3(h) --kallikrein-3(h)--> IGFBP3-p24(h) + protein remnants (cleavage)
IGFBP-3(h) --kallikrein-3(h)--> IGFBP3-p22(h) + protein remnants (cleavage)
IGFBP-3(h) --kallikrein-3(h)--> IGFBP3-p20(h) + protein remnants (cleavage)
IGFBP-3(h) --kallikrein-3(h)--> IGFBP3-p14(h) + protein remnants (cleavage)
TSP-1(h) + IGFBP-3(h) <==> TSP-1(h):IGFBP-3(h) (binding)
OPN(h) + IGFBP-3(h) <==> OPN(h):IGFBP-3(h) (binding)
IGFBP-3(h) + ADAM12-isoform2(h) <==> IGFBP-3(h):ADAM12-isoform2(h) (binding)
IGFBP-3(h) --ADAM12-isoform2(h)--> IGFBP3-p20(h) + protein remnants (cleavage)
IGFBP-3(h) --ADAM12-isoform2(h)--> IGFBP3-p10(h) + protein remnants (cleavage)
IGFBP3(h) --> IGFBP-3(h) (expression).
IGFBP-3(h) --> Bcl-2(h){pS} (increase of phosphorylation)
RXR-alpha(h) + IGFBP-3(h) <==> RXR-alpha(h):IGFBP-3(h) (binding)
RXR-alpha(m.s.) + IGFBP-3(h) <==> RXR-alpha(m.s.):IGFBP-3(h) (binding)
IGF-1(h) + IGFBP-3(h) <==> IGF-1(h):IGFBP-3(h) (binding)
IGF-2(h) + IGFBP-3(h) <==> IGF-2(h):IGFBP-3(h) (binding)
IGF-2(h) + IGFBP-3(h) <==> IGF-2(h):IGFBP-3(h) (binding)
ALS(h) + IGF-2(h) + IGFBP-3(h) <==> ALS(h):IGF-2(h):IGFBP-3(h) (binding)
ALS(h) + IGF-2(h) + IGFBP-3(h) <==> ALS(h):IGF-2(h):IGFBP-3(h) (binding)
IGFBP3(h) --> IGFBP-3(h) (expression).
TNF-alpha(v.s.) --> IGFBP-3(h) (increase of abundance)
5alphaDHT --/ IGFBP-3(h) (decrease of abundance)
testosterone --/ IGFBP-3(h) (decrease of abundance)
dehydroepiandrosterone --/ IGFBP-3(h) (decrease of abundance)

Human Primary Tumor Samples (U95)  | Top

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Human U133A/GNF1H Gene Atlas  | Top