lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

1111

PubMed (Gene Name)

Literature evidence

24113549 (CHEK1)

elevated expression in lung adenocarcinomas correlates with poor patient survival

24441772 (CHEK1)

It regulates signaling pathway in human lung cancercells.

25840419 (CHEK1)

CHEK1 was a direct target of miR-195, which decreased CHEK1 expression in lung cancer cells. High expression of CHEK1 in lung tumors was associated with poor overall survival.

27553023 (CHEK1)

High CHK1 expression is associated with increased radioresistance of non-small cell lung cancer.

29074359 (CHEK1)

Xanthatin functions as a DNA-damaging agent in non-small cell lung carcinomas by activating Chk1-mediated DDR and lysosome-mediated degradation of Cdc25C.

29138515 (CHEK1)

Targeting the ATR/CHK1 axis could result in reversing of drug resistance in small cell lung cancer.

31140586 (CHEK1)

Fbxo6 confers drug-sensitization to cisplatin via inhibiting the activation of Chk1 in non-small cell lung cancer

32161100 (CHEK1)

CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human lung and Colorectal cancer Cells.