| Gene ID | 1543 |
| Symbol | CYP1A1 |
| Synonymous | AHH|AHRR|CP11|CYP1|P1-450|P450-C|P450DX |
| Full name | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| Gene description | CYPIA1|aryl hydrocarbon hydroxylase|cytochrome P1-450, dioxin-inducible|cytochrome P450 1A1|cytochrome P450 form 6|cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1|cytochrome P450-C|cytochrome P450-P1|flavoprotein-linked monooxyge |
| Cytoband | 15q24.1 |
| Gene type | protein-coding |
| Synonymous | MIM:108330; HGNC:HGNC:2595; Ensembl:ENSG00000140465; HPRD:00148; Vega:OTTHUMG00000142812 |
Pathways and Diseases | Detail |
|---|---|
Pathway | Steroid hormone biosynthesis;KEGG PATHWAY;hsa00140 |
Pathway | Xenobiotics;PID Reactome;500197 |
Pathway | Metabolism of xenobiotics by cytochrome P450;KEGG PATHWAY;hsa00980 |
Pathway | Biological oxidations;Reactome;REACT:13433 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | Retinol metabolism;KEGG PATHWAY;hsa00830 |
Pathway | Tryptophan metabolism;KEGG PATHWAY;hsa00380 |
Disease | Lupus erythematosus;FunDO |
Disease | pneumonia;GAD |
Disease | Osteoporosis;FunDO |
Disease | liver disease;GAD |
Disease | Premature birth;FunDO |
Disease | HEMATOLOGICAL;GAD |
Disease | endometriosis;GAD |
Disease | Upper aerodigestive tract cancers;GAD |
Disease | Periodontitis;FunDO |
Disease | 1-hydroxypyrene, urinary;GAD |
Disease | leukemia, myeloid;GAD |
Disease | Cancer;FunDO |
Disease | bronchitis;GAD |
Disease | Psoriasis;FunDO |
Disease | arthritis;GAD |
Disease | AGING;GAD |
Disease | Acute Coronary Syndrome;GAD |
Disease | Parkinson disease;FunDO |
Disease | anemia, iron deficiency;GAD |
Disease | preterm delivery;GAD |
Disease | CYP1A1 genetic polymorphisms;GAD |
Disease | Cigarette Smoking. Coronary Artery Disease. and Diabetes;GAD |
Disease | breast cancer;GAD |
Disease | Amnionitis;FunDO |
Disease | Adenocarcinoma of the lung;GAD |
Disease | VISION;GAD |
Disease | IMMUNE;GAD |
Disease | Parkinson's disease;GAD |
Disease | coke-oven toxicity;GAD |
Disease | colorectal cancer;GAD |
Disease | Polycystic ovary syndrome;FunDO |
Disease | Aplastic anemia;FunDO |
Disease | Asthma;GAD |
Disease | Neck cancer;FunDO |
Disease | cancer susceptibility;GAD |
Disease | non-Hodgkin's lymphoma;GAD |
Disease | Stroke;FunDO |
Disease | INFECTION;GAD |
Disease | systemic lupus erythematosus;GAD |
Disease | psoriatic arthritis;GAD |
Disease | Diastolic blood pressure;GAD |
Disease | Primary biliary cirrhosis;FunDO |
Disease | esophageal cancer;GAD |
Disease | Diabetes mellitus;FunDO |
Disease | longevity;GAD |
Disease | laryngeal cancer;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | esophageal carcinoma;GAD |
Disease | blood pressure, arterial;GAD |
Disease | Diastolic blood pressure;NHGRI |
Disease | prostate cancer;GAD |
Disease | Endometriosis;FunDO |
Disease | METABOLIC;GAD |
Disease | Chronic obstructive airway disease;FunDO |
Disease | NEUROLOGICAL;GAD |
Disease | Behcet's Disease;GAD |
Disease | REPRODUCTION;GAD |
Disease | Behcet syndrome;FunDO |
Disease | DNA damage, biomarkers of;GAD |
Disease | Pancreatitis;FunDO |
Disease | liver cancer;GAD |
Disease | CANCER;GAD |
Disease | CYP1A1 polymorphisms;GAD |
Disease | cytogenetic studies;GAD |
Disease | smoking;GAD |
Disease | Spondylarthropathies;FunDO |
Disease | endometrial cancer;GAD |
Disease | lung cancer;GAD |
Disease | uterine fibroids;GAD |
Disease | Macular Degeneration;GAD |
Disease | Atherosclerosis;FunDO |
Disease | stomach cancer;GAD |
Disease | Arthritis;FunDO |
Sequence Information | |
|---|---|
Nucleotide Sequence | >1543 : length: 2685 ATCTCAGCTCGCTCCAGGGAAGGAGGCGTGGCCACACGTACAAGCCCGCCTATAAAGGTGGCAGTGCCTTCACCCTCACCCTGAAGGTGACAGTTCCTTGGAACCTTCCCTGATCCTTGT GATCCCAGGCTCCAAGAGTCCACCCTTCCCAGCTCAGCTCAGTACCTCAGCAGCCACCTCCAAGATCCCTACACTGATCATGCTTTTCCCAATCTCCATGTCGGCCACGGAGTTTCTTCT GGCCTCTGTCATCTTCTGTCTGGTATTCTGGGTAATCAGGGCCTCAAGACCTCAGGTCCCCAAAGGCCTGAAGAATCCACCAGGGCCATGGGGCTGGCCTCTGATTGGGCACATGCTGAC CCTGGGAAAGAACCCGCACCTGGCACTGTCAAGGATGAGCCAGCAGTATGGGGACGTGCTGCAGATCCGAATTGGCTCCACACCCGTGGTGGTGCTGAGCGGCCTGGACACCATCCGGCA GGCCCTGGTGCGGCAGGGCGATGATTTCAAGGGCCGGCCCGACCTCTACACCTTCACCCTCATCAGTAATGGTCAGAGCATGTCCTTCAGCCCAGACTCTGGACCAGTGTGGGCTGCCCG CCGGCGCCTGGCCCAGAATGGCCTGAAAAGTTTCTCCATTGCCTCTGACCCAGCCTCCTCAACCTCCTGCTACCTGGAAGAGCATGTGAGCAAGGAGGCTGAGGTCCTGATAAGCACGTT GCAGGAGCTGATGGCAGGGCCTGGGCACTTTAACCCCTACAGGTATGTGGTGGTATCAGTGACCAATGTCATCTGTGCCATTTGCTTTGGCCGGCGCTATGACCACAACCACCAAGAACT GCTTAGCCTAGTCAACCTGAATAATAATTTCGGGGAGGTGGTTGGCTCTGGAAACCCAGCTGACTTCATCCCTATTCTTCGCTACCTACCCAACCCTTCCCTGAATGCCTTCAAGGACCT GAATGAGAAGTTCTACAGCTTCATGCAGAAGATGGTCAAGGAGCACTACAAAACCTTTGAGAAGGGCCACATCCGGGACATCACAGACAGCCTGATTGAGCACTGTCAGGAGAAGCAGCT GGATGAGAACGCCAATGTCCAGCTGTCAGATGAGAAGATCATTAACATCGTCTTGGACCTCTTTGGAGCTGGGTTTGACACAGTCACAACTGCTATCTCCTGGAGCCTCATGTATTTGGT GATGAACCCCAGGGTACAGAGAAAGATCCAAGAGGAGCTAGACACAGTGATTGGCAGGTCACGGCGGCCCCGGCTCTCTGACAGATCCCATCTGCCCTATATGGAGGCCTTCATCCTGGA GACCTTCCGACACTCTTCCTTCGTCCCCTTCACCATCCCCCACAGCACAACAAGAGACACAAGTTTGAAAGGCTTTTACATCCCCAAGGGGCGTTGTGTCTTTGTAAACCAGTGGCAGAT CAACCATGACCAGAAGCTATGGGTCAACCCATCTGAGTTCCTACCTGAACGGTTTCTCACCCCTGATGGTGCTATCGACAAGGTGTTAAGTGAGAAGGTGATTATCTTTGGCATGGGCAA GCGGAAGTGTATCGGTGAGACCATTGCCCGCTGGGAGGTCTTTCTCTTCCTGGCTATCCTGCTGCAACGGGTGGAATTCAGCGTGCCACTGGGCGTGAAGGTGGACATGACCCCCATCTA TGGGCTAACCATGAAGCATGCCTGCTGTGAGCACTTCCAAATGCAGCTGCGCTCTTAGGTGCTTGAGAGCCCTGAGGCCTAGACTCTGTCTACCTGGTCTGGTTGGGCAGCCAGACCAGC AGGCTGGCCTATGTGGTCTAAGGTTCAGCCTGAAACTCATAGACACTGATCTGGCTGCAGTTTTGCTATCTGGGCTGTGGGCAAGCCTAAGGGATCCTGCCTGCCCCTACCCTGGACTTG CCTCTGCACACCCTCCAGAGACAACAGGTAAAACAGGGCCACATAGATGCTGATGGAGCCTTCCCAAGTTGTGCTTGAGCCAGGAGGCCTGCTAGGGTTAGGAGGTCCTTAGGCCTCTGA GAAGCTCTGAAGAACTCTCTGGAAGCCCCTGGGCCCAGTACCTAGCTGGCTCTGTGAGGGTGCTGACTGGCTTCAGCAAGTTAGAACTAGCCAAACCAGGACCCTGTCCAATCTTTGACA ATTGGGAGCTGCCAAGAGTGAAGGGAAGAGACAGCCCAGGATACTGGCACAGAGGTAGTCTCACTGCTTGAACTAGGCTGAGCAATCTGACCCTATGGGTCTAGGACACAGTTCCTGGGA ACATCACATTCCTCTGCCCTTCCTGCAGGCAGGAACAAACAGGGCTGCCTTCTGGCCTTGTAAGACCCTTATTGCTGTCCTGGAGGGGCTGGGGACTTGTGTCTGCGGGGATCAGAGCGC ACAGGGAGTGCACATATCCAGGCACCAGGACTAGGGCTGGAGTGAGGGGGGGGTATTTCAATTACCTTCTATTGGTCTCCCTTCTCTACACTCTTGTAATAAAATGTCTATTTTTAATGT TTGTACACAACAATCCTTCTATTCTAGCCTGCATTGAGCTTGCATGCTTGCATAAGAGCTTAAGAACCATTGATTTAATGTAATAGGGAAAATTCTAACCCAGGTATCCAAAAATGTGTA AGAACAACTACCTGAGCTAAATAAAGATATTGTTCAGAAATCCTA |
Protein Sequence | >1543 : length: 512 MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQS MSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPIL RYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS DRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEF SVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS |