| Tyk2(h) + ATP --protein tyrosine kinases(v.s.)--> Tyk2(h){pY} + ADP (phosphorylation)
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IL-13Ralpha1(h) + Tyk2(h) <==> IL-13Ralpha1(h):Tyk2(h) (binding)
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IFNAR1(h) + Tyk2(h) <==> IFNAR1(h):Tyk2(h) (binding)
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Tyk2(h) + Jak1(h) <==> Tyk2(h):Jak1(h) (binding)
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Tyk2(h) + Jak1(m) <==> Tyk2(h):Jak1(m) (binding)
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2 Tyk2(h) <==> Tyk2(h):Tyk2(h) (binding)
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Tyk2(h) + ATP --Tyk2(h)--> Tyk2(h){pY} + ADP (phosphorylation)
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Tyk2(h) + uPAR(h) <==> Tyk2(h):uPAR(h) (binding)
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Tyk2(h) + ATP --> Tyk2(h){pY} + ADP (phosphorylation)
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Tyk2(h) + ATP --> Tyk2(h){p} + ADP (phosphorylation)
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IL-17A(h) --> Tyk2(h) (activation; phosphorylation)
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TYK2(h) --> Tyk2(h) (expression).
|
Tyk2(h) + ATP --Tyk2(h)--> Tyk2(h){pY} + ADP (phosphorylation)
|
Tyk2(h) + ATP --> Tyk2(h){pY} + ADP (phosphorylation)
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IFNAR1-isoform1(h) + Tyk2(h) <==> IFNAR1-isoform1(h):Tyk2(h) (binding)
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Tyk2(h) + 2 ATP --> Tyk2(h){pY1054}{pY1055} + 2 ADP (phosphorylation)
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Tyk2(h) + ATP --> Tyk2(h){p} + ADP (automodification)
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Tyk2(h) + ATP --> Tyk2(h){pY292} + ADP (phosphorylation)
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TYK2(h) --> Tyk2(h) (expression).
|
IFNAR1(h) + ATP --Tyk2(h)--> IFNAR1(h){p} + ADP (phosphorylation)
|
Beta-enolase(rb) + ATP --Tyk2(h)--> Beta-enolase(rb){p} + ADP (phosphorylation)
|
