| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 8945 |
Name | BTRC |
Synonymous | BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP;beta-transducin repeat containing;BTRC;beta-transducin repeat containing |
Definition | E3RSIkappaB|F-box and WD repeats protein beta-TrCP|F-box and WD-repeat protein 1B|F-box/WD repeat-containing protein 1A|beta-TrCP1|pIkappaBalpha-E3 receptor subunit |
Position | 10q24.32 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | beta-TrCP1(h) + Cul-1(h) + Skp1(h) <==> beta-TrCP1(h):Cul-1(h):Skp1(h) (binding) | beta-TrCP1(h) + Cul-1(h){nedd} + Skp1(h) <==> beta-TrCP1(h):Cul-1(h){nedd}:Skp1(h) (binding) | beta-TrCP1(h) + Skp1(h) <==> beta-TrCP1(h):Skp1(h) (binding) | beta-TrCP1(h) + plakoglobin(h) <==> beta-TrCP1(h):plakoglobin(h) (binding) | beta-catenin(x) + beta-TrCP1(h) <==> beta-catenin(x):beta-TrCP1(h) (binding) | beta-catenin(h) + beta-TrCP1(h) <==> beta-catenin(h):beta-TrCP1(h) (binding) | apc(h) + beta-catenin(h) + beta-TrCP1(h) <==> apc(h):beta-catenin(h):beta-TrCP1(h) (binding) | beta-TrCP1(h) + Wee1(h) <==> beta-TrCP1(h):Wee1(h) (binding) | beta-TrCP1(h) + Wee1(h){pS53}{pS123} <==> beta-TrCP1(h):Wee1(h){pS53}{pS123} (binding) | beta-TrCP1(h) + Cdc25A(h){p} <==> beta-TrCP1(h):Cdc25A(h){p} (binding) | beta-TrCP1(h) + Cul-1(h) <==> beta-TrCP1(h):Cul-1(h) (binding) | beta-TrCP1(h) + Cdc25A(h) <==> beta-TrCP1(h):Cdc25A(h) (binding) | beta-TrCP1(h) + NF-kappaB2-p100(h) <==> beta-TrCP1(h):NF-kappaB2-p100(h) (binding) | beta-TrCP1(h) + NF-kappaB1(m.s.){pS927}{pS932} <==> beta-TrCP1(h):NF-kappaB1(m.s.){pS927}{pS932} (binding) | beta-TrCP1(h) + trim9(h) <==> beta-TrCP1(h):trim9(h) (binding) | BTRC(h) --> beta-TrCP1(h) (expression). | beta-catenin(x) + n ubiquitin(m) --beta-TrCP1(h)--> beta-catenin(x){ub(n)} (ubiquitination) | plakoglobin(h) + n ubiquitin(m) --beta-TrCP1(h)--> plakoglobin(h){ub(n)} (ubiquitination) | p100(m.s.) + n ubiquitin(m.s.) --E1(h),Ubc5C(m.s.),beta-TrCP1(h)--> p100(m.s.){ub(n)K855} (ubiquitination) | p100(m.s.) + n ubiquitin(m.s.) --E1(h),Ubc5C(m.s.),beta-TrCP1(h)--> p100(m.s.){p}{ub}n (ubiquitination) | Emi1(h){p} + beta-TrCPl(h) <==> Emi1(h){p}:beta-TrCPl(h) (binding) | BTRC(h) --> beta-TrCPl(h) (expression). | Emi1(h){p} + beta-TrCPs(h) <==> Emi1(h){p}:beta-TrCPs(h) (binding) | BTRC(h) --> beta-TrCPs(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for BTRC | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 103102315 - 103104315 | Agilent_014791 |
chr10 |
Promoter: 103102315 - 103104315 | GSE27584 |
chr10 |
Promoter: 103102315 - 103104315 | GSE27584 |
chr10 |
Promoter: 103102315 - 103104315 | Agilent_014791_44K |
chr10 |
Promoter: 103102315 - 103104315 | Agilent_014791 |