| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 8793 |
Name | TNFRSF10D |
Synonymous | CD264|DCR2|TRAIL-R4|TRAILR4|TRUNDD;tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain;TNFRSF10D;tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
Definition | TNF receptor-related receptor for TRAIL|TNF-related apoptosis-inducing ligand receptor 4|TRAIL receptor 4|TRAIL receptor with a truncated death domain|decoy receptor 2|decoy with truncated death domain|tumor necrosis factor receptor superfamily member 10D |
Position | 8p21 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Apo2L(h) + DCR2(h) <==> Apo2L(h):DCR2(h) (binding) | DCR2(h) + LRP130(h) <==> DCR2(h):LRP130(h) (binding) | DCR2(h) + MYH10(h) <==> DCR2(h):MYH10(h) (binding) | DCR2(h) + phosphoribosylformylglycinamidine synthase(h) <==> DCR2(h):phosphoribosylformylglycinamidine synthase(h) (binding) | DCR2(h) + STAF130(h) <==> DCR2(h):STAF130(h) (binding) | DCR2(h) + RNF96(h) <==> DCR2(h):RNF96(h) (binding) | DCR2(h) + GIF(h) <==> DCR2(h):GIF(h) (binding) | DCR2(h) --26S proteasome(h)--> protein remnants (degradation) | TNFRSF10D(h) --> DCR2(h) (expression). | IFNgamma(m.s.) --/ DCR2(h) (decrease of abundance) | IFNalpha(m.s.) --/ DCR2(h) (decrease of abundance) | TNFRSF10D(h) --> DCR2(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 127 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 182 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr8 |
Promoter: 23076985 - 23078985 | Agilent_014791 |
chr8 |
Promoter: 23076985 - 23078985 | GoldenGate_Methylation_Cancer_Panel_I |
chr8 |
Promoter: 23076985 - 23078985 | GSE27584 |
chr8 |
Promoter: 23076985 - 23078985 | Agilent_014791_44K |
chr8 |
Promoter: 23076985 - 23078985 | PMID:11929838 |
chr8 |
Promoter: 23076985 - 23078985 | PMID:15788647 |
chr8 |
Promoter: 23076985 - 23078985 | PMID:16616114 |
chr8 |
Promoter: 23076985 - 23078985 | PMID:16644104 |
chr8 |
Promoter: 23076985 - 23078985 | PMID:14999791 |
chr8 |
Promoter: 23076985 - 23078985 | PMID:17139617 |