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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8792

Name

TNFRSF11A

Synonymous

CD265|FEO|LOH18CR1|ODFR|OFE|OPTB7|OSTS|PDB2|RANK|TRANCER;tumor necrosis factor receptor superfamily, member 11a, NFKB activator;TNFRSF11A;tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Definition

loss of heterozygosity, 18, chromosomal region 1|osteoclast differentiation factor receptor|receptor activator of NF-KB|receptor activator of nuclear factor-kappa B|tumor necrosis factor receptor superfamily member 11A|tumor necrosis factor receptor super

Position

18q22.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

RANK(h) + TRAF2(m) <==> RANK(h):TRAF2(m) (binding)
RANK(h) + TRAF5(m) <==> RANK(h):TRAF5(m) (binding)
RANK(h) + TRAF6(m) <==> RANK(h):TRAF6(m) (binding)
RANKL(m) + RANK(h) <==> RANKL(m):RANK(h) (binding)
RANK(h) + TRAF2(h) <==> RANK(h):TRAF2(h) (binding)
RANK(h) + TRAF5(h) <==> RANK(h):TRAF5(h) (binding)
RANK(h) + TRAF6(h) <==> RANK(h):TRAF6(h) (binding)
RANK(h) + TAK1(h) <==> RANK(h):TAK1(h) (binding)
RANK(h) + TAB2(h) <==> RANK(h):TAB2(h) (binding)
RANK(h) + TAK1(h) + TAB1(h) <==> RANK(h):TAK1(h):TAB1(h) (binding)
RANK(h) + TRAF6(h) + TAB2(h) <==> RANK(h):TRAF6(h):TAB2(h) (binding)
RANK(h) + TRAF1(h) <==> RANK(h):TRAF1(h) (binding)
RANK(h) + TRAF3(h) <==> RANK(h):TRAF3(h) (binding)
RANKL-2(h) + RANK(h) <==> RANKL-2(h):RANK(h) (binding)
TNFRSF11A(h) --> RANK(h) (expression).
TNFRSF11A(h) --> RANK(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

105N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
174N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr18

Promoter: 58142028 - 58144028Agilent_014791

chr18

Promoter: 58142028 - 58144028GSE27584

chr18

Promoter: 58142028 - 58144028Agilent_014791_44K


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