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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

862

Name

RUNX1T1

Synonymous

AML1T1|CBFA2T1|CDR|ETO|MTG8|ZMYND2;runt-related transcription factor 1; translocated to, 1 (cyclin D-related);RUNX1T1;runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

Definition

acute myelogenous leukemia 1 translocation 1, cyclin-D related|core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related|eight twenty one protein|myeloid translocation gene on 8q22|protein CBFA2T1|zinc finger MYND domain-cont

Position

8q22

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

PLZF(h) + MTG8(h) <==> PLZF(h):MTG8(h) (binding)
atrophin-1(m.s.) + MTG8(h) <==> atrophin-1(m.s.):MTG8(h) (binding)
MTG8(h) + MTG8B(h) <==> MTG8(h):MTG8B(h) (binding)
sin3a(h) + MTG8(h) <==> sin3a(h):MTG8(h) (binding)
hdac2(h) + MTG8(h) <==> hdac2(h):MTG8(h) (binding)
sin3a(h) + NCOR(h) + HDAC1(h) + MTG8(h) <==> sin3a(h):NCOR(h):HDAC1(h):MTG8(h) (binding)
MTG8(h) + HIN1(h) <==> MTG8(h):HIN1(h) (binding)
MTG8(h) + TRAP150(h) <==> MTG8(h):TRAP150(h) (binding)
MTG8(h) + NESH(h) <==> MTG8(h):NESH(h) (binding)
MTG8(h) + TAF(II)31L(h) <==> MTG8(h):TAF(II)31L(h) (binding)
MTG8(h) + SIPP1(h) <==> MTG8(h):SIPP1(h) (binding)
MTG8(h) + EFCBP2(h) <==> MTG8(h):EFCBP2(h) (binding)
MTG8(h) + c19orf57(h) <==> MTG8(h):c19orf57(h) (binding)
RUNX1T1(h) --> MTG8(h) (expression).
RUNX1T1(h) --> MTG8A(h) (expression).
MTG8B(h) + NCOR(m.s.) <==> MTG8B(h):NCOR(m.s.) (binding)
MTG8B(h) + HDAC8(h) <==> MTG8B(h):HDAC8(h) (binding)
MTG8B(h) + HDAC3(h) <==> MTG8B(h):HDAC3(h) (binding)
MTG8B(h) + hdac2(h) <==> MTG8B(h):hdac2(h) (binding)
HDAC1(h) + MTG8B(h) <==> HDAC1(h):MTG8B(h) (binding)
sin3a(mo) + MTG8B(h) <==> sin3a(mo):MTG8B(h) (binding)
sin3a(m.s.) + MTG8B(h) <==> sin3a(m.s.):MTG8B(h) (binding)
sin3a(h) + MTG8B(h) <==> sin3a(h):MTG8B(h) (binding)
2 MTG8B(h) <==> (MTG8B(h))2 (oligomerization)
MTG8(h) + MTG8B(h) <==> MTG8(h):MTG8B(h) (binding)
MTG8B(h) + NCOR(h) <==> MTG8B(h):NCOR(h) (binding)
MTG8B(h) + NCOR(mo) <==> MTG8B(h):NCOR(mo) (binding)
NCOR1-isoform1(m) + MTG8B(h) <==> NCOR1-isoform1(m):MTG8B(h) (binding)
RUNX1T1(h) --> MTG8B(h) (expression).

Post Translational Modification   [Top]

There is no record for RUNX1T1

Methylation Profile   [Top]

Chromosome

Location

Source

chr8

Promoter: 93176119 - 93178119Agilent_014791

chr8

Promoter: 93176119 - 93178119GoldenGate_Methylation_Cancer_Panel_I

chr8

Promoter: 93143867 - 93145867GSE27584


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