| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 83990 |
Name | BRIP1 |
Synonymous | BACH1|FANCJ|OF;BRCA1 interacting protein C-terminal helicase 1;BRIP1;BRCA1 interacting protein C-terminal helicase 1 |
Definition | ATP-dependent RNA helicase BRIP1|BRCA1-associated C-terminal helicase 1|BRCA1-binding helicase-like protein BACH1|BRCA1/BRCA2-associated helicase 1|Fanconi anemia group J protein |
Position | 17q22.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | brca1(h) + BRIP1(h) <==> brca1(h):BRIP1(h) (binding) | brca1(m.s.) + BRIP1(h) <==> brca1(m.s.):BRIP1(h) (binding) | BRIP1(h) + ATP --> BRIP1(h){pS990} + ADP (phosphorylation) | BRIP1(h) --> BRIP1(h) (expression). | BRIP1(h) --> BRIP1(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 990 | Phosphoserine. | Swiss-Prot 53.0 | 1032 | Phosphoserine. | Swiss-Prot 53.0 | 1032 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 990 | Phosphoserine | 15125843 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr17 |
Promoter: 57295037 - 57297037 | Agilent_014791 |
chr17 |
Promoter: 57295037 - 57297037 | GSE27584 |
chr17 |
Promoter: 57295037 - 57297037 | Agilent_014791_44K |