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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

83605

Name

CCM2

Synonymous

C7orf22|OSM;cerebral cavernous malformation 2;CCM2;cerebral cavernous malformation 2

Definition

cerebral cavernous malformations 2 protein|malcavernin

Position

7p13

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

ErbB1-p170(h){pY998} + CCM2(h) <==> ErbB1-p170(h){pY998}:CCM2(h) (binding)
KRIT1(h) + MEKK3(m.s.) + CCM2(h) <==> KRIT1(h):MEKK3(m.s.):CCM2(h) (binding)
MEKK3(m.s.) + CCM2(h) <==> MEKK3(m.s.):CCM2(h) (binding)
KRIT1(h) + CCM2(h) <==> KRIT1(h):CCM2(h) (binding)
CCM2(h) --> CCM2(h) (translocation)
KRIT1(h) + CCM2(h) + ICAP-1alpha(h) <==> KRIT1(h):CCM2(h):ICAP-1alpha(h) (binding)
CCM2(h) --> CCM2(h) (expression).
CCM2(h) --> CCM2(h) (translocation)
CCM2(h) --> CCM2(h) (expression).

Post Translational Modification   [Top]

There is no record for CCM2

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 45004812 - 45006812Agilent_014791

chr7

Promoter: 45032010 - 45034010GSE27584

chr7

Promoter: 45004812 - 45006812GSE27584

chr7

Promoter: 45004812 - 45006812Agilent_014791_44K


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