| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 80824 |
Name | DUSP16 |
Synonymous | MKP-7|MKP7;dual specificity phosphatase 16;DUSP16;dual specificity phosphatase 16 |
Definition | MAP kinase phosphatase 7|MAPK phosphatase-7|dual specificity protein phosphatase 16|mitogen-activated protein kinase phosphatase 7 |
Position | 12p13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | DUSP16(h) --> MKP-7(h) (expression). | beta-arrestin2(h) + MKP-7(h) <==> beta-arrestin2(h):MKP-7(h) (binding) | JIP1(m.s.) + MKP-7(h) <==> JIP1(m.s.):MKP-7(h) (binding) | JNK3(m.s.) + MKP-7(h) <==> JNK3(m.s.):MKP-7(h) (binding) | MKP-7(h) --> JNK3(m.s.){p} (decrease of phosphorylation) | DUSP16(h) --> MKP-7(h) (expression). | beta-arrestin2(h):MKP-7(h) --> MKP-7(h) + beta-arrestin2(h) (dissociation) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 446 | Phosphoserine (MAPK1) | 12794087 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr12 |
Promoter: 12606084 - 12608084 | GSE27584 |
chr12 |
Promoter: 12606084 - 12608084 | Agilent_014791 |