| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 7508 |
Name | XPC |
Synonymous | RAD4|XP3|XPCC;xeroderma pigmentosum, complementation group C;XPC;xeroderma pigmentosum, complementation group C |
Definition | DNA repair protein complementing XP-C cells|mutant xeroderma pigmentosum group C|p125 |
Position | 3p25 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | XPC(h) --> XPC(h) (expression). | XPC(h) + sumo1(h) --> XPC(h){sumo} (sumoylation) | XPC(h) + ubiquitin(h) --> XPC(h){ub} (ubiquitination) | XPC(h) --> XPC(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 94 | Phosphoserine. | Swiss-Prot 53.0 | 883 | Phosphoserine. | Swiss-Prot 53.0 | 884 | Phosphoserine. | Swiss-Prot 53.0 | 883 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 882 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 93 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 116 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 121 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 128 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 357 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr3 |
Promoter: 14194643 - 14196643 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 14194643 - 14196643 | GSE27584 |
chr3 |
Promoter: 14194643 - 14196643 | Agilent_014791_44K |
chr3 |
Promoter: 14194643 - 14196643 | PMID:17325666 |