Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7468

Name

WHSC1

Synonymous

MMSET|NSD2|REIIBP|TRX5|WHS;Wolf-Hirschhorn syndrome candidate 1;WHSC1;Wolf-Hirschhorn syndrome candidate 1

Definition

IL5 promoter REII region-binding protein|multiple myeloma SET domain containing protein type III|nuclear SET domain-containing protein 2|probable histone-lysine N-methyltransferase NSD2|trithorax/ash1-related protein 5

Position

4p16.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

WHSC1(h) --> probable histone-lysine N-methyltransferase NSD2 isoform-1(h) (expression).
WHSC1(h) --> probable histone-lysine N-methyltransferase NSD2(h) (expression).
WHSC1(h) --> probable histone-lysine N-methyltransferase NSD2 isoform-2(h) (expression).
WHSC1(h) --> probable histone-lysine N-methyltransferase NSD2 isoform-3(h) (expression).
WHSC1(h) --> probable histone-lysine N-methyltransferase NSD2 isoform-4(h) (expression).
WHSC1(h) --> probable histone-lysine N-methyltransferase NSD2 isoform-5(h) (expression).
WHSC1(h) --> probable histone-lysine N-methyltransferase NSD2 isoform-6(h) (expression).
WHSC1(h) --> probable histone-lysine N-methyltransferase NSD2 isoform-7(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

544Phosphothreonine.Swiss-Prot 53.0
544Phosphothreonine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr4

Promoter: 1862807 - 1864807GSE27584

chr4

Promoter: 1862807 - 1864807GSE27584

chr4

Promoter: 1862807 - 1864807GSE27584

chr4

Promoter: 1862807 - 1864807GSE27584

chr4

Promoter: 1841421 - 1843421GSE27584


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