Entrez Gene

Basic Information
Gene ID	7253
Name	TSHR
Synonymous	CHNG1\|LGR3\|hTSHR-I;thyroid stimulating hormone receptor;TSHR;thyroid stimulating hormone receptor
Definition	TSH-R\|seven transmembrane helix receptor\|thyroid-stimulating hormone receptor\|thyrotropin receptor\|thyrotropin receptor-I, hTSHR-I
Position	14q31
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
TSH-R(h) + MRC(m) <==> TSH-R(h):MRC(m) (binding)
TSH-R(h) --> IFNgamma(m) (increase of secretion)
TSH(b) + TSH-R(h) <==> TSH(b):TSH-R(h) (binding)
scribble(h) + TSH-R(h) <==> scribble(h):TSH-R(h) (binding)
TSHR(h) --> TSH-R(h) (expression).
TSH-R(h){gly}n --> TSH-R(h) + NDP-Gly (deglycosylation)
TSH(b) + TSH-R-long(h) <==> TSH(b):TSH-R-long(h) (binding)
scribble-isoform1(h) + TSH-R-long(h) <==> scribble-isoform1(h):TSH-R-long(h) (binding)
scribble(h) + TSH-R-long(h) <==> scribble(h):TSH-R-long(h) (binding)
TSHR(h) --> TSH-R-long(h) (expression).
TSHR(h) --> TSH-R-short(h) (expression).

Location (AA)	PTM type	Database
Post Translational Modification [Top]
77	N-linked (GlcNAc...).	Swiss-Prot 53.0
99	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
113	N-linked (GlcNAc...).	Swiss-Prot 53.0
177	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
198	N-linked (GlcNAc...).	Swiss-Prot 53.0
302	N-linked (GlcNAc...).	Swiss-Prot 53.0

Transcription Factors [Top]