Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7187

Name

TRAF3

Synonymous

CAP-1|CD40bp|CRAF1|LAP1;TNF receptor-associated factor 3;TRAF3;TNF receptor-associated factor 3

Definition

CD40 associated protein 1|CD40 binding protein|CD40 receptor associated factor 1|LMP1-associated protein 1

Position

14q32.32

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

TRAF3(h) + NIK(h) <==> TRAF3(h):NIK(h) (binding)
cd40(h) + TRAF3(h) <==> cd40(h):TRAF3(h) (binding)
EDAR(h) + TRAF3(h) <==> EDAR(h):TRAF3(h) (binding)
XEDAR-L(h) + TRAF3(h) <==> XEDAR-L(h):TRAF3(h) (binding)
RANK(h) + TRAF3(h) <==> RANK(h):TRAF3(h) (binding)
cd40(h) + cIAP-1(h) + TRAF2(h) + TRAF3(h) + TRAF5(h) + TRAF6(h) <==> cd40(h):cd40(h):cd40(h):TRAF2(h):TRAF3(h):TRAF5(h):TRAF6(h):cIAP-1(h) (binding)
TRAF3(h) + CIKS(h) <==> TRAF3(h):CIKS(h) (binding)
TRAF3(h) + NIK(h) <==> TRAF3(h):NIK(h) (binding)
TRAF3(h) + MyD88(m) <==> TRAF3(h):MyD88(m) (binding)
TRAF3(h) + TANK(h) + TBK1(m.s.) <==> TRAF3(h):TANK(h):TBK1(m.s.) (binding)
TANK(h) + TRAF3(h) <==> TANK(h):TRAF3(h) (binding)
TRAF3(h) + n ubiquitin(h) --> TRAF3(h){ub{K48}(n)} (ubiquitination)
TRAF3(h) + n ubiquitin(h) --> TRAF3(h){ub{K63}(n)} (ubiquitination)
TRAF3(h) + TRIAD3A(h) <==> TRAF3(h):TRIAD3A(h) (binding)
TRAF3(h) --> TRAF3(h) (expression).
TRIAD3(h) --/ TRAF3(h) (decrease of abundance)
TRAF3(h) + p75NTR(r) <==> TRAF3(h):p75NTR(r) (binding)
TRAF3(h) + NIK(h) <==> TRAF3(h):NIK(h) (binding)
TRAF3(h) + NIK(m.s.) <==> TRAF3(h):NIK(m.s.) (binding)
RANK(m.s.) + TRAF3(h) <==> RANK(m.s.):TRAF3(h) (binding)
TRAF3(h) + CD30(m.s.) <==> TRAF3(h):CD30(m.s.) (binding)
TRAF3(h) + LT-betaR(m.s.) <==> TRAF3(h):LT-betaR(m.s.) (binding)
TRAF3(h) + BCMA(m.s.) <==> TRAF3(h):BCMA(m.s.) (binding)
TRAF3(h) + HVEM(m.s.) <==> TRAF3(h):HVEM(m.s.) (binding)
TRAF3(h) + TNFR2(m.s.) <==> TRAF3(h):TNFR2(m.s.) (binding)
TRAF3(h) + TACI(m.s.) <==> TRAF3(h):TACI(m.s.) (binding)
TRAF3(h) + cd40(m.s.) <==> TRAF3(h):cd40(m.s.) (binding)
TRAF3(h) + TNFRSF7(m.s.) <==> TRAF3(h):TNFRSF7(m.s.) (binding)
TRAF3(h) + TNFRSF18(m.s.) <==> TRAF3(h):TNFRSF18(m.s.) (binding)
TRAF3(h) + 4-1BB(m.s.) <==> TRAF3(h):4-1BB(m.s.) (binding)
TRAF3(h) + OX40(m.s.) <==> TRAF3(h):OX40(m.s.) (binding)
TRIAD3A(h) + TRAF3(h) <==> TRIAD3A(h):TRAF3(h) (binding)
TRAF3(h) + n ubiquitin(h) --TRIAD3A(h)--> TRAF3(h){ub{K48}(n)} (ubiquitination)
TRAF3(h) --> TRAF3(h) (expression).

Post Translational Modification   [Top]

There is no record for TRAF3

Methylation Profile   [Top]

Chromosome

Location

Source

chr14

Promoter: 102312069 - 102314069GSE27584

chr14

Promoter: 102312069 - 102314069GSE27584

chr14

Promoter: 102312069 - 102314069GSE27584

chr14

Promoter: 102312069 - 102314069Agilent_014791_44K


')