| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 7097 |
Name | TLR2 |
Synonymous | CD282|TIL4;toll-like receptor 2;TLR2;toll-like receptor 2 |
Definition | toll/interleukin 1 receptor-like 4|toll/interleukin-1 receptor-like protein 4 |
Position | 4q32 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | LPS:LBP(rb):CD14(h) + TLR2(h) <==> LPS:LBP(rb):CD14(h):TLR2(h) (binding) | TLR2(h) + TRIF(h) <==> TLR2(h):TRIF(h) (binding) | PGN(STAAU) + TLR2(h) <==> PGN(STAAU):TLR2(h) (binding) | CD14(h) + TLR2(h) <==> CD14(h):TLR2(h) (binding) | TLR2(h) + LPG(LEIMA) <==> TLR2(h):LPG(LEIMA) (binding) | TLR2(h) + TLR6(h) <==> TLR2(h):TLR6(h) (binding) | TLR2(h) + GP4(h) <==> TLR2(h):GP4(h) (binding) | TLR2(h) --> DEFB4(h) (transactivation) | TLR2(h) --> Beta-defensin2(h) (increase of secretion) | TLR2(h) --> TLR2(h) (expression). | TLR2(h) + tollip(m.s.) <==> TLR2(h):tollip(m.s.) (binding) | TLR2(h) + NDP-Gly --> TLR2(h){gly} + NMP (glycosylation) | TLR2(h) + TLR10(h) <==> TLR2(h):TLR10(h) (binding) | TLR2(h) + CD14(h) <==> TLR2(h):CD14(h) (binding) | TLR2(h) + MD-2(h) <==> TLR2(h):MD-2(h) (binding) | TLR1(h) + TLR2(h) <==> TLR1(h):TLR2(h) (binding) | TLR2(h) + TLR4-isoform1(h) <==> TLR2(h):TLR4-isoform1(h) (binding) | TLR1(m.s.) + TLR2(h) <==> TLR1(m.s.):TLR2(h) (binding) | 2 TLR2(h) <==> (TLR2(h))2 (binding; oligomerization) | TLR2(h) + Trap-2(h) <==> TLR2(h):Trap-2(h) (binding) | TLR2(h) + MyD88(m.s.) <==> TLR2(h):MyD88(m.s.) (binding) | TLR2(h) + n ubiquitin(h) --> TLR2(h){ub}n (ubiquitination) | TLR2(h) + Rac1(h) <==> TLR2(h):Rac1(h) (binding) | TLR2(h) + Rac1(m.s.) <==> TLR2(h):Rac1(m.s.) (binding) | TLR2(h) + ATP --> TLR2(h){pY} + ADP (phosphorylation) | TLR2(h) + p85alpha(h) <==> TLR2(h):p85alpha(h) (binding) | TLR2(h) --> TLR2(h) (expression). | TLR2(h) --> TLR2(h) (expression). | hsa-miR-105 --/ TLR2(h) (translational repression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 114 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 199 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 414 | N-linked (GlcNAc...) (Probable). | Swiss-Prot 53.0 | 442 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr4 |
Promoter: 154823391 - 154825391 | Agilent_014791 |
chr4 |
Promoter: 154823391 - 154825391 | GSE27584 |