| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 6839 |
Name | SUV39H1 |
Synonymous | KMT1A|MG44|SUV39H;suppressor of variegation 3-9 homolog 1 (Drosophila);SUV39H1;suppressor of variegation 3-9 homolog 1 (Drosophila) |
Definition | H3-K9-HMTase 1|Su(var)3-9 homolog 1|histone H3-K9 methyltransferase 1|histone-lysine N-methyltransferase SUV39H1|histone-lysine N-methyltransferase, H3 lysine-9 specific 1|lysine N-methyltransferase 1A|position-effect variegation 3-9 homolog |
Position | Xp11.23 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | SUV39H1(h) --> SUV39H1(h) (expression). | histone H3(m) + S-adenosylmethionine --SUV39H1(h)--> histone H3(m){met} + S-adenosylhomocysteine (methylation) | histone H3(h) + S-adenosylmethionine --SUV39H1(h)--> histone H3(h){met} + S-adenosylhomocysteine (methylation) | histone H3(m) + 2 S-adenosylmethionine --SUV39H1(h)--> histone H3(m){met(2)} + 2 S-adenosylhomocysteine (methylation) | histone H3(h) + 2 S-adenosylmethionine --SUV39H1(h)--> histone H3(h){met(2)} + 2 S-adenosylhomocysteine (methylation) | histone H3(m) + 3 S-adenosylmethionine --SUV39H1(h)--> histone H3(m){met(3)} + 3 S-adenosylhomocysteine (methylation) | histone H3(h) + 3 S-adenosylmethionine --SUV39H1(h)--> histone H3(h){met(3)} + 3 S-adenosylhomocysteine (methylation) | histone H4(m) + S-adenosylmethionine --SUV39H1(h)--> histone H4(m){met} + S-adenosylhomocysteine (methylation) | histone H4(h) + S-adenosylmethionine --SUV39H1(h)--> histone H4(h){met} + S-adenosylhomocysteine (methylation) | HDAC1(h) + SUV39H1(h) <==> HDAC1(h):SUV39H1(h) (binding) | hdac2(h) + SUV39H1(h) <==> hdac2(h):SUV39H1(h) (binding) | HDAC3(h) + SUV39H1(h) <==> HDAC3(h):SUV39H1(h) (binding) | SUV39H1(h) + Tal-1(h) <==> SUV39H1(h):Tal-1(h) (binding) | SUV39H1(h) + Hp1-alpha(h) <==> SUV39H1(h):Hp1-alpha(h) (binding) | SUV39H1(h) --> CENP-B(h) (increase of abundance) | SUV39H1(h) --> CENP-C(h) (increase of abundance) | SUV39H1(h) --> SUV39H1(h) (expression). | histone H3(h) + S-adenosylmethionine --SUV39H1(h)--> histone H3(h){met} + S-adenosylhomocysteine (methylation) | histone H3(h) + 3 S-adenosylmethionine --SUV39H1(h)--> histone H3(h){met(3)K10} + 3 S-adenosylhomocysteine (methylation) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 391 | Phosphoserine. | Swiss-Prot 53.0 | 391 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chrX |
Promoter: 48438575 - 48440575 | Agilent_014791 |
chrX |
Promoter: 48438575 - 48440575 | GSE27584 |
chrX |
Promoter: 48438575 - 48440575 | Agilent_014791_44K |