Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6663

Name

SOX10

Synonymous

DOM|PCWH|WS2E|WS4|WS4C;SRY (sex determining region Y)-box 10;SOX10;SRY (sex determining region Y)-box 10

Definition

SRY-related HMG-box gene 10|dominant megacolon, mouse, human homolog of|transcription factor SOX-10

Position

22q13.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

Sox10(h) --> Egr2(m) (transactivation)
Sox10(h) --> EDNRB(h) (transactivation)
Sox10(h) --> MITF(h) (transactivation)
SOX10(h) --> Sox10(h) (expression).
Sox10(h) --> MITF(h) (DNA binding; transactivation).
dlx5(m) + Sox10(h) <==> dlx5(m):Sox10(h) (binding)
C/EBPalpha(r) + Sox10(h) <==> C/EBPalpha(r):Sox10(h) (binding)
c-Jun(r) + Sox10(h) <==> c-Jun(r):Sox10(h) (binding)
Krox20-isoform1(r) + Sox10(h) <==> Krox20-isoform1(r):Sox10(h) (binding)
OLIG2(m) + Sox10(h) <==> OLIG2(m):Sox10(h) (binding)
Sox10(h) --> MITF(h) (transactivation)
Sox10(h) --> EDNRB(h) (DNA binding; transactivation).
Sox10(h) --> GJB1(h) (DNA binding; transactivation).
SOX10(h) --> Sox10(h) (expression).

Post Translational Modification   [Top]

There is no record for SOX10

Methylation Profile   [Top]

There is no record for SOX10



')