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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6591

Name

SNAI2

Synonymous

SLUG|SLUGH1|SNAIL2|WS2D;snail homolog 2 (Drosophila);SNAI2;snail homolog 2 (Drosophila)

Definition

neural crest transcription factor SLUG|protein snail homolog 2|slug (chicken homolog), zinc finger protein|zinc finger protein SNAI2

Position

8q11

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

slug(h) --> BRCA2(h) (DNA binding).
slug(h) --26S proteasome(h)--> protein remnants (degradation)
mdm2(h) + p53(h) + slug(h) <==> mdm2(h):p53(h):slug(h) (binding)
SLUG(h) --> slug(h) (expression).
mdm2(h) --/ slug(h) (decrease of abundance)
p53(h) --/ slug(h) (decrease of abundance)
slug(h) + mdm2(h) <==> slug(h):mdm2(h) (binding)
slug(h) + n ubiquitin(h) --mdm2(h)--> slug(h){ub(n)} (ubiquitination)
slug(h) + p53(h) <==> slug(h):p53(h) (binding)
mdm2(h) + slug(h) + p53(h) <==> mdm2(h):slug(h):p53(h) (binding)
slug(h) --/ HPGD(h) (transrepression)
SLUG(h) --> slug(h) (expression).
p53(h) --/ slug(h) (decrease of abundance)

Post Translational Modification   [Top]

There is no record for SNAI2

Methylation Profile   [Top]

Chromosome

Location

Source

chr8

Promoter: 49996041 - 49998041Agilent_014791

chr8

Promoter: 49996041 - 49998041GSE27584


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