Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6469

Name

SHH

Synonymous

HHG1|HLP3|HPE3|MCOPCB5|SMMCI|TPT|TPTPS;sonic hedgehog;SHH;sonic hedgehog

Definition

sonic hedgehog homolog|sonic hedgehog protein

Position

7q36

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

Shh(h) --> PTCH1(h) (transactivation)
Shh(h) + cholesterol --> Shh-C(h) + Shh-N(h){chol} (cleavage; cholesterol modification)
SHH(h) --> Shh(h) (expression).
SHH(h) --> Shh(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

24N-palmitoyl cysteine.Swiss-Prot 53.0
197Cholesterol glycine ester (Bysimilarity).Swiss-Prot 53.0
278N-linked (GlcNAc...).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 155297228 - 155299228Agilent_014791

chr7

Promoter: 155297228 - 155299228GoldenGate_Methylation_Cancer_Panel_I

chr7

Promoter: 155297228 - 155299228GSE27584

chr7

Promoter: 155297228 - 155299228Agilent_014791_44K


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