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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5624

Name

PROC

Synonymous

APC|PC|PROC1;protein C (inactivator of coagulation factors Va and VIIIa);PROC;protein C (inactivator of coagulation factors Va and VIIIa)

Definition

anticoagulant protein C|autoprothrombin IIA|blood coagulation factor XIV|vitamin K-dependent protein C

Position

2q13-q14

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

PROC(h) --> mmp2(h) (activation)
PROC(h) + EPCR(h) <==> PROC(h):EPCR(h) (binding)
Protein C precursor(h) --> PROC(h) (expression).
Protein C precursor(h) --> PROC(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

484-carboxyglutamate.Swiss-Prot 53.0
494-carboxyglutamate.Swiss-Prot 53.0
564-carboxyglutamate.Swiss-Prot 53.0
584-carboxyglutamate.Swiss-Prot 53.0
614-carboxyglutamate.Swiss-Prot 53.0
624-carboxyglutamate.Swiss-Prot 53.0
674-carboxyglutamate.Swiss-Prot 53.0
684-carboxyglutamate.Swiss-Prot 53.0
714-carboxyglutamate.Swiss-Prot 53.0
1133-hydroxyaspartate.Swiss-Prot 53.0
139N-linked (GlcNAc...).Swiss-Prot 53.0
290N-linked (GlcNAc...).Swiss-Prot 53.0
355N-linked (GlcNAc...).Swiss-Prot 53.0
371N-linked (GlcNAc...); partial; atypical.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr2

Promoter: 127890987 - 127892987Agilent_014791

chr2

Promoter: 127890987 - 127892987GSE27584


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