| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 5308 |
Name | PITX2 |
Synonymous | ARP1|Brx1|IDG2|IGDS|IGDS2|IHG2|IRID2|Otlx2|PTX2|RGS|RIEG|RIEG1|RS;paired-like homeodomain 2;PITX2;paired-like homeodomain 2 |
Definition | ALL1-responsive protein ARP1|all1-responsive gene 1|homeobox protein PITX2|paired-like homeodomain transcription factor 2|pituitary homeo box 2|pituitary homeobox 2|rieg bicoid-related homeobox transcription factor 1|solurshin |
Position | 4q25 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | pitx2(h) + Pit-1A(r) <==> pitx2(h):Pit-1A(r) (binding). | Pit-1(m.s.) + pitx2(h) <==> Pit-1(m.s.):pitx2(h) (binding) | pitx2(h) --> PRL(r) (transactivation) | pitx2(h) --> pitx2(h) (expression). | pitx2a(h) --> PLOD1(h) (DNA binding; transregulation). | pitx2a(h) --> Plod2(m) (DNA binding). | pitx2a(h) --> PLOD1(h) (DNA binding; transactivation). | pitx2a(h) --> Nppa(r) (DNA binding; transactivation). | mef2a(h) + pitx2a(h) <==> mef2a(h):pitx2a(h) (binding) | pitx2a(h) --> Nppa(r) (transactivation) | pitx2a(h) --> Gad1(m) (transactivation) | pitx2a(h) --> Pomc(r) (DNA binding). | pitx2a(h) --> prl(h) (DNA binding; transactivation). | PITX2(h) --> pitx2a(h) (expression). | pitx2c(h) --> Nppa(r) (DNA binding; transactivation). | pitx2c(h) --> PLOD1(h) (DNA binding; transactivation). | PITX2(h) --> pitx2c(h) (expression). | pitx2b(h) --> Nppa(r) (DNA binding; transactivation). | pitx2b(h) --> PLOD1(h) (DNA binding; transactivation). | PITX2(h) --> pitx2b(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for PITX2 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr4 |
Promoter: 111763203 - 111765203 | Agilent_014791 |
chr4 |
Promoter: 111777457 - 111779457 | Agilent_014791 |
chr4 |
Promoter: 111777457 - 111779457 | GoldenGate_Methylation_Cancer_Panel_I |
chr4 |
Promoter: 111777457 - 111779457 | GoldenGate_Methylation_Cancer_Panel_I |
chr4 |
Promoter: 111763203 - 111765203 | GSE27584 |
chr4 |
Promoter: 111777457 - 111779457 | GSE27584 |
chr4 |
Promoter: 111777457 - 111779457 | GSE27584 |
chr4 |
Promoter: 111763203 - 111765203 | Agilent_014791_44K |
chr4 |
Promoter: 111763203 - 111765203 | PMID:11313277 |
chr4 |
Promoter: 111777457 - 111779457 | PMID:11313277 |
chr4 |
Promoter: 111777457 - 111779457 | PMID:11313277 |