| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 5265 |
Name | SERPINA1 |
Synonymous | A1A|A1AT|AAT|PI|PI1|PRO2275|alpha1AT;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1;SERPINA1;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
Definition | alpha-1 protease inhibitor|alpha-1-antiproteinase|alpha-1-antitrypsin|alpha-1-antitrypsin null|protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin|serine (or cysteine) proteinase inhibitor, clade A, member 1|serpin A1 |
Position | 14q32.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | alpha1-AT(h) --> Alpha-1-antitrypsin(h) (expression). | catalase(m.s.) --> Alpha-1-antitrypsin(h) (regulation of protein activity) | alpha1-AT(h) --> Alpha 1antitrypsin-isoform1(h) (expression). | alpha1-AT(h) --> Alpha 1antitrypsin-isoform2(h) (expression). | alpha1-AT(h) --> Alpha 1antitrypsin-isoform3(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 70 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 107 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 271 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr14 |
Promoter: 93924404 - 93926404 | GSE27584 |
chr14 |
Promoter: 93926282 - 93928282 | GSE27584 |
chr14 |
Promoter: 93926282 - 93928282 | GSE27584 |