Pediatric cancer gene database (Pedican) Home
Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5155

Name

PDGFB

Synonymous

PDGF2|SIS|SSV|c-sis;platelet-derived growth factor beta polypeptide;PDGFB;platelet-derived growth factor beta polypeptide

Definition

PDGF subunit B|PDGF, B chain|PDGF-2|Platelet-derived growth factor, beta polypeptide (oncogene SIS)|becaplermin|platelet-derived growth factor 2|platelet-derived growth factor B chain|platelet-derived growth factor beta polypeptide (simian sarcoma viral (

Position

22q12.3-q13.1|22q13.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

PDGFB(h) --> PDGFRbeta(h) (activation)
PDGFB(h) --> PDGFB(h) (expression).
PDGFB(h) --> RhoE(m){pS11} (activation; increase of phosphorylation)
PDGFB(h) --> PDGFB(h) (expression).

Post Translational Modification   [Top]

There is no record for PDGFB

Methylation Profile   [Top]

Chromosome

Location

Source

chr22

Promoter: 37970436 - 37972436Agilent_014791

chr22

Promoter: 37966365 - 37968365Agilent_014791

chr22

Promoter: 37970436 - 37972436GoldenGate_Methylation_Cancer_Panel_I

chr22

Promoter: 37966365 - 37968365GSE27584

chr22

Promoter: 37970436 - 37972436GSE27584

chr22

Promoter: 37970436 - 37972436Agilent_014791_44K


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