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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5087

Name

PBX1

Synonymous

-;pre-B-cell leukemia homeobox 1;PBX1;pre-B-cell leukemia homeobox 1

Definition

homeobox protein PBX1|homeobox protein PRL|pre-B-cell leukemia transcription factor 1

Position

1q23

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

Pbx1a(h) --> uPA(h) (DNA binding).
Pbx1a(h) --> HOXB1(m) (DNA binding).
Pbx1a(h) + Prep1(h) <==> Pbx1a(h):Prep1(h) (binding).
Pbx1a(h) --> HOXB2(m) (DNA binding).
Pbx1a(h) + PKNOX2(h) <==> Pbx1a(h):PKNOX2(h) (binding).
Pbx1a(h) --> COL5A2(h) (DNA binding; transactivation).
hoxa9(m) + Pbx1a(h) + meis1b(m.s.) <==> hoxa9(m):Pbx1a(h):meis1b(m.s.) (binding)
Pbx1a(h) + hoxa9(m) <==> Pbx1a(h):hoxa9(m) (binding)
Pbx1(h) --> Pbx1a(h) (expression).
Pbx1b(h) --> uPA(h) (DNA binding).
Pbx1b(h) --> HOXB1(m) (DNA binding; transregulation).
Prep1(h) + Pbx1b(h) <==> Pbx1b(h):Prep1(h) (binding).
Pbx1b(h) + Oct-1(h) <==> Pbx1b(h):Oct-1(h) (binding)
Pbx1(h) --> Pbx1b(h) (expression).
BAF60c1(h) + Pbx1(h) <==> BAF60c1(h):Pbx1(h) (binding)
BAF60c2(h) + Pbx1(h) <==> BAF60c2(h):Pbx1(h) (binding)
Pbx1(h) + Cdx-2(lh) <==> Pbx1(h):Cdx-2(lh) (binding)
foxc1(h) + Pbx1(h) <==> foxc1(h):Pbx1(h) (binding)
Pbx1(h) --> IL10(h) (DNA binding).
HOXA10(h) + Pbx1(h) + hdac2(h) <==> HOXA10(h):Pbx1(h):hdac2(h) (binding)
Pbx1(h) --> Pbx1(h) (expression).

Post Translational Modification   [Top]

There is no record for PBX1

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 162794061 - 162796061GSE27584

chr1

Promoter: 162794061 - 162796061E-GEOD-20553


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