Entrez Gene

Basic Information
Gene ID	4982
Name	TNFRSF11B
Synonymous	OCIF\|OPG\|TR1;tumor necrosis factor receptor superfamily, member 11b;TNFRSF11B;tumor necrosis factor receptor superfamily, member 11b
Definition	osteoclastogenesis inhibitory factor\|osteoprotegerin\|tumor necrosis factor receptor superfamily member 11B
Position	8q24
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Apo2L(m) + OPG(h) <==> Apo2L(m):OPG(h) (binding)
Apo2L(h) + OPG(h) <==> Apo2L(h):OPG(h) (binding)
RANKL(m) + OPG(h) <==> RANKL(m):OPG(h) (binding)
RANKL-2(h) + OPG(h) <==> RANKL-2(h):OPG(h) (binding)
TNFRSF11B(h) --> OPG(h) (expression).
Apo2L(h) + OPG(h) <==> OPG(h):Apo2L(h) (binding)
OPG(h) + RANKL(h) <==> OPG(h):RANKL(h) (binding)
OPG(h) --> icam1(h) (increase of abundance)
OPG(h) --> vcam1(h) (increase of abundance)
OPG(h) --> E-selectin(h) (increase of abundance)
OPG(h) --> VCAM1(h) (transactivation)
OPG(h) --> SELE(h) (transactivation)
TNFRSF11B(h) --> OPG(h) (expression).

Location (AA)	PTM type	Database
Post Translational Modification [Top]
98	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
152	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
165	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
178	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
289	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Transcription Factors [Top]