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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4908

Name

NTF3

Synonymous

HDNF|NGF-2|NGF2|NT3;neurotrophin 3;NTF3;neurotrophin 3

Definition

NT-3|nerve growth factor 2|neurotrophic factor|neurotrophin-3

Position

12p13

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

NTF3(h) --> NT-3(h) (expression).
MATH1(m.s.) --> NT-3(h) (increase of abundance)
2 NT-3(h) <==> (NT-3(h))2 (oligomerization)
NT-3(h) + BDNF(h) <==> NT-3(h):BDNF(h) (binding)
trkA(h) + NT-3(h) <==> trkA(h):NT-3(h) (binding)
NT-3(h) + trkA(m.s.) <==> NT-3(h):trkA(m.s.) (binding)
NGF(m) + NT-3(h) <==> NGF(m):NT-3(h) (binding)
NT-5(h) + NT-3(h) <==> NT-5(h):NT-3(h) (binding)
NT-3(h) --> FOXO3a(r){pT32}{pS253} (increase of phosphorylation)
NT-3(h) --> AKT(r){p} (increase of phosphorylation)
NT-3(h) --> CREB1(r){pS133} (increase of phosphorylation)
NT-3(h) --> Fos(m) (transactivation)
NT-3(h) --> Dusp1(m) (transactivation)
NT-3(h) --> NR4A2(m) (transactivation)
NT-3(h) --> DOK5(m.s.){pY} (increase of phosphorylation)
NT-3(h) --> ERK1(h){p} (increase of phosphorylation)
NT-3(h) --> ERK2(h){p} (increase of phosphorylation)
NT-3(h) --> GRIN2C(m) (transactivation)
NT-3(h) --> AKT-1(r){pS473} (increase of phosphorylation)
NT-3(h) --> ERK1(r){pT203}{pY205} (increase of phosphorylation)
NT-3(h) --> ERK2(r){pT183}{pY185} (increase of phosphorylation)
NT-3(h) --> IRS-1(r){pY} (increase of phosphorylation)
NT-3(h) --> ERK1(m){pY} (increase of phosphorylation)
NT-3(h) --> FRS2alpha(m){pY} (increase of phosphorylation)
NTF3(h) --> NT-3(h) (expression).

Post Translational Modification   [Top]

There is no record for NTF3

Methylation Profile   [Top]

There is no record for NTF3



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