| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4602 |
Name | MYB |
Synonymous | Cmyb|c-myb|c-myb_CDS|efg;v-myb myeloblastosis viral oncogene homolog (avian);MYB;v-myb myeloblastosis viral oncogene homolog (avian) |
Definition | c-myb protein (140 AA)|c-myb10A_CDS|c-myb13A_CDS|c-myb14A_CDS|c-myb8B_CDS|proto-oncogene c-Myb|transcriptional activator Myb |
Position | 6q22-q23 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | c-Myb(h) --> c-myb(h) (DNA binding). | ATBF1-B(h) + c-Myb(h) <==> ATBF1-B(h):c-Myb(h) (binding). | c-Myb(h) + acetyl-CoA --p300(h)--> c-Myb(h){ace} + CoA (acetylation) | c-Myb(h) + 3 acetyl-CoA --p300(h)--> c-Myb(h){aceK471}{aceK480}{aceK485} + 3 CoA (acetylation) | c-Myb(h) + sumo1(h) --> c-Myb(h){sumo} (sumoylation) | c-Myb(h) --> ADA(h) (DNA binding; transactivation). | c-Myb(h) --> TRHR(h) (DNA binding; transactivation). | c-Myb(h) --> Pbsn(m) (DNA binding). | c-Myb(h) --> NR3C1(h) (DNA binding). | c-Myb(h) --> GSTP1(h) (transactivation) | c-Myb(h) --> mim-1(c) (DNA binding). | c-Myb(h) --> SP3(h) (DNA binding). | c-Myb(h) --> MIRN15A(h) (DNA binding). | c-Myb(h) --> SIM2(h) (DNA binding). | c-Myb(h) --> MAT2A(h) (DNA binding). | c-Myb(h) --> COL1A2(h) (DNA binding; transactivation). | c-Myb(h) --/ IGFBP5(h) (DNA binding; transrepression). | c-Myb(h) --> PRTN3(h) (DNA binding). | c-Myb(h) --> SLC34A2(h) (DNA binding). | c-Myb(h) --> Atp2b1(m) (DNA binding). | c-myb(h) --> c-Myb(h) (expression). | c-Myb-isoform1(h) --> SFRS2(h) (DNA binding). | c-Myb-isoform1(h) --> CDC2(h) (DNA binding). | c-Myb-isoform1(h) --> KIT(h) (DNA binding; transactivation). | c-Myb-isoform1(h) + 2 sumo1(mo) --> c-Myb-isoform1(h){sumoK503}{sumoK527} (sumoylation) | c-Myb-isoform1(h) + 2 sumo1(h) --Aos1(mo):SAE2(mo),Ubc9(h)--> c-Myb-isoform1(h){sumoK503}{sumoK527} (sumoylation) | c-Myb-isoform1(h) + Ubc9(h) <==> c-Myb-isoform1(h):Ubc9(h) (binding) | c-Myb-isoform1(h) --> LECT2(c) (transactivation) | c-myb(h) --> c-Myb-isoform1(h) (expression). | c-myb(h) --> c-Myb-isoform2(h) (expression). | c-myb(h) --> c-Myb-isoform3(h) (expression). | c-myb(h) --> c-Myb-isoform4(h) (expression). | c-myb(h) --> c-Myb-isoform5(h) (expression). | c-myb(h) --> c-Myb-isoform6(h) (expression). | c-myb(h) --> c-Myb(h) (expression). | hsa-miR-15a --/ c-Myb(h) (translational repression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr6 |
Promoter: 135542646 - 135544646 | Agilent_014791 |
chr6 |
Promoter: 135542646 - 135544646 | GoldenGate_Methylation_Cancer_Panel_I |
chr6 |
Promoter: 135542646 - 135544646 | GSE27584 |
chr6 |
Promoter: 135542646 - 135544646 | Agilent_014791_44K |