Entrez Gene

Basic Information
Gene ID	4297
Name	MLL
Synonymous	ALL-1\|CXXC7\|HRX\|HTRX1\|KMT2A\|MLL/GAS7\|MLL1A\|TET1-MLL\|TRX1;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);MLL;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
Definition	CDK6/MLL fusion protein\|CXXC-type zinc finger protein 7\|MLL-AF4 der(11) fusion protein\|MLL/GAS7 fusion protein\|MLL/GMPS fusion protein\|histone-lysine N-methyltransferase MLL\|lysine N-methyltransferase 2A\|trithorax-like protein\|zinc finger protein HRX
Position	11q23
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
HCF1(h) + ALL1(h) <==> HCF1(h):ALL1(h) (binding)
ALL1(h) + HCF1-isoform1(h) <==> ALL1(h):HCF1-isoform1(h) (binding)
ALL1(h) + HCF2(h) <==> ALL1(h):HCF2(h) (binding)
ALL1(h) --> ALL1-p180(h) + ALL1-p320(h) (cleavage)
ALL1(h) --taspase1(h)--> ALL1-p180(h) + protein remnants (cleavage)
MLL(h) --> ALL1(h) (expression).
ALL1-isoform1(h) + TAF(II)31(h) <==> ALL1-isoform1(h):TAF(II)31(h) (binding)
ALL1-isoform1(h) --> ALL1-isoform1-p180(h) + ALL1-isoform1-p320(h) (cleavage)
MLL(h) --> ALL1-isoform1(h) (expression).
MLL(h) --> ALL1-isoform2(h) (expression).

Post Translational Modification [Top]
	There is no record for MLL

Transcription Factors [Top]