| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4255 |
Name | MGMT |
Synonymous | -;O-6-methylguanine-DNA methyltransferase;MGMT;O-6-methylguanine-DNA methyltransferase |
Definition | 6-O-methylguanine-DNA methyltransferase|O-6-methylguanine-DNA-alkyltransferase|O6-methylguanine-DNA methyltransferase|methylated-DNA--protein-cysteine methyltransferase|methylguanine-DNA methyltransferase |
Position | 10q26 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | SMC1(h) + MGMT(h) <==> SMC1(h):MGMT(h) (binding) | mcm3(h) + MGMT(h) <==> mcm3(h):MGMT(h) (binding) | MGMT(h) + TopoI(h) <==> MGMT(h):TopoI(h) (binding) | DNA-PKcs(h) + MGMT(h) <==> DNA-PKcs(h):MGMT(h) (binding) | Ku70(h) + MGMT(h) <==> Ku70(h):MGMT(h) (binding) | MGMT(h) + p68(h) <==> MGMT(h):p68(h) (binding) | DDX24(h) + MGMT(h) <==> DDX24(h):MGMT(h) (binding) | RNF8(h) + MGMT(h) <==> RNF8(h):MGMT(h) (binding) | PA28beta(h) + MGMT(h) <==> PA28beta(h):MGMT(h) (binding) | psmd1(h) + MGMT(h) <==> psmd1(h):MGMT(h) (binding) | FBX2(h) + MGMT(h) <==> FBX2(h):MGMT(h) (binding) | FBX27(h) + MGMT(h) <==> FBX27(h):MGMT(h) (binding) | MGMT(h) + Hsp90-alpha(h) <==> MGMT(h):Hsp90-alpha(h) (binding) | Hsp90-beta(h) + MGMT(h) <==> Hsp90-beta(h):MGMT(h) (binding) | CRK7(h) + MGMT(h) <==> CRK7(h):MGMT(h) (binding) | CDK10(h) + MGMT(h) <==> CDK10(h):MGMT(h) (binding) | PKCeta(h) + MGMT(h) <==> PKCeta(h):MGMT(h) (binding) | PRP4K(h) + MGMT(h) <==> PRP4K(h):MGMT(h) (binding) | STK9(h) + MGMT(h) <==> STK9(h):MGMT(h) (binding) | SET(h) + MGMT(h) <==> SET(h):MGMT(h) (binding) | PTN4(h) + MGMT(h) <==> PTN4(h):MGMT(h) (binding) | MGMT(h) + 14-3-3zeta(h) <==> MGMT(h):14-3-3zeta(h) (binding) | importin-beta1(h) + MGMT(h) <==> importin-beta1(h):MGMT(h) (binding) | WNT14B(h) + MGMT(h) <==> WNT14B(h):MGMT(h) (binding) | PABP3(h) + MGMT(h) <==> PABP3(h):MGMT(h) (binding) | PP32(h) + MGMT(h) <==> PP32(h):MGMT(h) (binding) | nucleolin(h) + MGMT(h) <==> nucleolin(h):MGMT(h) (binding) | hnrnpa2b1(h) + MGMT(h) <==> hnrnpa2b1(h):MGMT(h) (binding) | MGMT(h) + hnRNP-C(h) <==> MGMT(h):hnRNP-C(h) (binding) | rps15a(h) + MGMT(h) <==> rps15a(h):MGMT(h) (binding) | MGMT(h) + RRP1(h) <==> MGMT(h):RRP1(h) (binding) | MGMT(h) + eIF-3gamma(h) <==> MGMT(h):eIF-3gamma(h) (binding) | MGMT(h) + EEF1A(h) <==> MGMT(h):EEF1A(h) (binding) | MGMT(h) + EF1A2(h) <==> MGMT(h):EF1A2(h) (binding) | MGMT(h) + EF1B(h) <==> MGMT(h):EF1B(h) (binding) | ANT2(h) + MGMT(h) <==> ANT2(h):MGMT(h) (binding) | ANT3(h) + MGMT(h) <==> ANT3(h):MGMT(h) (binding) | MGMT(h) + PKM2(h) <==> MGMT(h):PKM2(h) (binding) | TTPA(h) + MGMT(h) <==> TTPA(h):MGMT(h) (binding) | IL-17E(h) + MGMT(h) <==> IL-17E(h):MGMT(h) (binding) | FBL(h) + MGMT(h) <==> FBL(h):MGMT(h) (binding) | TUBB2(h) + MGMT(h) <==> TUBB2(h):MGMT(h) (binding) | alpha-tubulin 6(h) + MGMT(h) <==> alpha-tubulin 6(h):MGMT(h) (binding) | Annexin A1(h) + MGMT(h) <==> Annexin A1(h):MGMT(h) (binding) | annexin-A2(h) + MGMT(h) <==> annexin-A2(h):MGMT(h) (binding) | beta-actin(h) + MGMT(h) <==> beta-actin(h):MGMT(h) (binding) | vimentin(h) + MGMT(h) <==> vimentin(h):MGMT(h) (binding) | MGMT(h) + Myosin-7A(h) <==> MGMT(h):Myosin-7A(h) (binding) | Phb(h) + MGMT(h) <==> Phb(h):MGMT(h) (binding) | SRP9(h) + MGMT(h) <==> SRP9(h):MGMT(h) (binding) | MGMT(h) + SSRP1(h) <==> MGMT(h):SSRP1(h) (binding) | PCNA(h) + MGMT(h) <==> PCNA(h):MGMT(h) (binding) | Cdk2(h) + MGMT(h) <==> Cdk2(h):MGMT(h) (binding) | Cdk1(h) + MGMT(h) <==> Cdk1(h):MGMT(h) (binding) | cyclinB1(h) + MGMT(h) <==> cyclinB1(h):MGMT(h) (binding) | p21Cip1(h) + MGMT(h) <==> p21Cip1(h):MGMT(h) (binding) | mcm2(h) + MGMT(h) <==> mcm2(h):MGMT(h) (binding) | ORC1(h) + MGMT(h) <==> ORC1(h):MGMT(h) (binding) | Pold(h) + MGMT(h) <==> Pold(h):MGMT(h) (binding) | Hsp90(h) + MGMT(h) <==> Hsp90(h):MGMT(h) (binding) | MGMT(h) --> MGMT(h) (expression). | MGMT(h) --> MGMT(h) (expression). |
|---|
Post Translational Modification [Top] | |||
There is no record for MGMT | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 131153956 - 131155956 | Agilent_014791 |
chr10 |
Promoter: 131153956 - 131155956 | GoldenGate_Methylation_Cancer_Panel_I |
chr10 |
Promoter: 131153956 - 131155956 | GSE27584 |
chr10 |
Promoter: 131153956 - 131155956 | Agilent_014791_44K |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17352030 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:20563638 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15367334 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15455376 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15450401 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12744471 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11577014 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15746058 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12579314 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16609952 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17080717 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:10029064 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12684420 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15297393 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16983315 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14654541 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15365725 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15892004 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15029256 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15279712 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11487055 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15455350 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16051033 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16391867 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12503076 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12826052 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15526363 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16174854 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15386372 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17339237 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15760919 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17183069 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15122305 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:10811111 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11406538 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12000733 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15389252 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:10078936 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17372756 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16436636 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11221863 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15800999 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16902913 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17378912 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17276933 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16336454 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15476557 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12538473 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11719438 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11196170 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16870044 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12684406 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16043258 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15201980 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12467239 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11895880 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12941804 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12473584 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15639718 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14742312 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15943786 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15073103 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11956078 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15758578 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11519041 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12695555 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14556664 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12746473 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15616773 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12763209 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16108828 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16475210 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11872960 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14507661 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15831994 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17369979 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11753949 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17139167 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14675710 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15589597 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11448914 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15785933 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16928264 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15099958 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12773202 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15713962 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16477636 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15870861 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12807758 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15703815 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16685400 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11309301 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15217927 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14555992 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15289362 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12660028 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16858686 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11773279 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14743506 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15623627 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12845678 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16170165 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17363525 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12149142 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16889486 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12584167 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16537562 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16258509 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14501508 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15184253 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15173091 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15635575 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11221887 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12124340 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16849682 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15154012 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:11839665 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16764763 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12478658 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15467712 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12213730 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15975525 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12672028 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16791592 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15254699 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14970867 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16740754 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16061849 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16303245 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16374457 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15064737 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:17034532 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15172987 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16867861 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12942643 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16166431 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16711019 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15283294 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15695118 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15959912 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12082624 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15201966 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12730870 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15915369 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:16258501 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:14527906 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12632081 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:15197802 |
chr10 |
Promoter: 131153956 - 131155956 | PMID:12545168 |