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Pedican
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4255

Name

MGMT

Synonymous

-;O-6-methylguanine-DNA methyltransferase;MGMT;O-6-methylguanine-DNA methyltransferase

Definition

6-O-methylguanine-DNA methyltransferase|O-6-methylguanine-DNA-alkyltransferase|O6-methylguanine-DNA methyltransferase|methylated-DNA--protein-cysteine methyltransferase|methylguanine-DNA methyltransferase

Position

10q26

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

SMC1(h) + MGMT(h) <==> SMC1(h):MGMT(h) (binding)
mcm3(h) + MGMT(h) <==> mcm3(h):MGMT(h) (binding)
MGMT(h) + TopoI(h) <==> MGMT(h):TopoI(h) (binding)
DNA-PKcs(h) + MGMT(h) <==> DNA-PKcs(h):MGMT(h) (binding)
Ku70(h) + MGMT(h) <==> Ku70(h):MGMT(h) (binding)
MGMT(h) + p68(h) <==> MGMT(h):p68(h) (binding)
DDX24(h) + MGMT(h) <==> DDX24(h):MGMT(h) (binding)
RNF8(h) + MGMT(h) <==> RNF8(h):MGMT(h) (binding)
PA28beta(h) + MGMT(h) <==> PA28beta(h):MGMT(h) (binding)
psmd1(h) + MGMT(h) <==> psmd1(h):MGMT(h) (binding)
FBX2(h) + MGMT(h) <==> FBX2(h):MGMT(h) (binding)
FBX27(h) + MGMT(h) <==> FBX27(h):MGMT(h) (binding)
MGMT(h) + Hsp90-alpha(h) <==> MGMT(h):Hsp90-alpha(h) (binding)
Hsp90-beta(h) + MGMT(h) <==> Hsp90-beta(h):MGMT(h) (binding)
CRK7(h) + MGMT(h) <==> CRK7(h):MGMT(h) (binding)
CDK10(h) + MGMT(h) <==> CDK10(h):MGMT(h) (binding)
PKCeta(h) + MGMT(h) <==> PKCeta(h):MGMT(h) (binding)
PRP4K(h) + MGMT(h) <==> PRP4K(h):MGMT(h) (binding)
STK9(h) + MGMT(h) <==> STK9(h):MGMT(h) (binding)
SET(h) + MGMT(h) <==> SET(h):MGMT(h) (binding)
PTN4(h) + MGMT(h) <==> PTN4(h):MGMT(h) (binding)
MGMT(h) + 14-3-3zeta(h) <==> MGMT(h):14-3-3zeta(h) (binding)
importin-beta1(h) + MGMT(h) <==> importin-beta1(h):MGMT(h) (binding)
WNT14B(h) + MGMT(h) <==> WNT14B(h):MGMT(h) (binding)
PABP3(h) + MGMT(h) <==> PABP3(h):MGMT(h) (binding)
PP32(h) + MGMT(h) <==> PP32(h):MGMT(h) (binding)
nucleolin(h) + MGMT(h) <==> nucleolin(h):MGMT(h) (binding)
hnrnpa2b1(h) + MGMT(h) <==> hnrnpa2b1(h):MGMT(h) (binding)
MGMT(h) + hnRNP-C(h) <==> MGMT(h):hnRNP-C(h) (binding)
rps15a(h) + MGMT(h) <==> rps15a(h):MGMT(h) (binding)
MGMT(h) + RRP1(h) <==> MGMT(h):RRP1(h) (binding)
MGMT(h) + eIF-3gamma(h) <==> MGMT(h):eIF-3gamma(h) (binding)
MGMT(h) + EEF1A(h) <==> MGMT(h):EEF1A(h) (binding)
MGMT(h) + EF1A2(h) <==> MGMT(h):EF1A2(h) (binding)
MGMT(h) + EF1B(h) <==> MGMT(h):EF1B(h) (binding)
ANT2(h) + MGMT(h) <==> ANT2(h):MGMT(h) (binding)
ANT3(h) + MGMT(h) <==> ANT3(h):MGMT(h) (binding)
MGMT(h) + PKM2(h) <==> MGMT(h):PKM2(h) (binding)
TTPA(h) + MGMT(h) <==> TTPA(h):MGMT(h) (binding)
IL-17E(h) + MGMT(h) <==> IL-17E(h):MGMT(h) (binding)
FBL(h) + MGMT(h) <==> FBL(h):MGMT(h) (binding)
TUBB2(h) + MGMT(h) <==> TUBB2(h):MGMT(h) (binding)
alpha-tubulin 6(h) + MGMT(h) <==> alpha-tubulin 6(h):MGMT(h) (binding)
Annexin A1(h) + MGMT(h) <==> Annexin A1(h):MGMT(h) (binding)
annexin-A2(h) + MGMT(h) <==> annexin-A2(h):MGMT(h) (binding)
beta-actin(h) + MGMT(h) <==> beta-actin(h):MGMT(h) (binding)
vimentin(h) + MGMT(h) <==> vimentin(h):MGMT(h) (binding)
MGMT(h) + Myosin-7A(h) <==> MGMT(h):Myosin-7A(h) (binding)
Phb(h) + MGMT(h) <==> Phb(h):MGMT(h) (binding)
SRP9(h) + MGMT(h) <==> SRP9(h):MGMT(h) (binding)
MGMT(h) + SSRP1(h) <==> MGMT(h):SSRP1(h) (binding)
PCNA(h) + MGMT(h) <==> PCNA(h):MGMT(h) (binding)
Cdk2(h) + MGMT(h) <==> Cdk2(h):MGMT(h) (binding)
Cdk1(h) + MGMT(h) <==> Cdk1(h):MGMT(h) (binding)
cyclinB1(h) + MGMT(h) <==> cyclinB1(h):MGMT(h) (binding)
p21Cip1(h) + MGMT(h) <==> p21Cip1(h):MGMT(h) (binding)
mcm2(h) + MGMT(h) <==> mcm2(h):MGMT(h) (binding)
ORC1(h) + MGMT(h) <==> ORC1(h):MGMT(h) (binding)
Pold(h) + MGMT(h) <==> Pold(h):MGMT(h) (binding)
Hsp90(h) + MGMT(h) <==> Hsp90(h):MGMT(h) (binding)
MGMT(h) --> MGMT(h) (expression).
MGMT(h) --> MGMT(h) (expression).

Post Translational Modification   [Top]

There is no record for MGMT

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

Promoter: 131153956 - 131155956Agilent_014791

chr10

Promoter: 131153956 - 131155956GoldenGate_Methylation_Cancer_Panel_I

chr10

Promoter: 131153956 - 131155956GSE27584

chr10

Promoter: 131153956 - 131155956Agilent_014791_44K

chr10

Promoter: 131153956 - 131155956PMID:17352030

chr10

Promoter: 131153956 - 131155956PMID:20563638

chr10

Promoter: 131153956 - 131155956PMID:15367334

chr10

Promoter: 131153956 - 131155956PMID:15455376

chr10

Promoter: 131153956 - 131155956PMID:15450401

chr10

Promoter: 131153956 - 131155956PMID:12744471

chr10

Promoter: 131153956 - 131155956PMID:11577014

chr10

Promoter: 131153956 - 131155956PMID:15746058

chr10

Promoter: 131153956 - 131155956PMID:12579314

chr10

Promoter: 131153956 - 131155956PMID:16609952

chr10

Promoter: 131153956 - 131155956PMID:17080717

chr10

Promoter: 131153956 - 131155956PMID:10029064

chr10

Promoter: 131153956 - 131155956PMID:12684420

chr10

Promoter: 131153956 - 131155956PMID:15297393

chr10

Promoter: 131153956 - 131155956PMID:16983315

chr10

Promoter: 131153956 - 131155956PMID:14654541

chr10

Promoter: 131153956 - 131155956PMID:15365725

chr10

Promoter: 131153956 - 131155956PMID:15892004

chr10

Promoter: 131153956 - 131155956PMID:15029256

chr10

Promoter: 131153956 - 131155956PMID:15279712

chr10

Promoter: 131153956 - 131155956PMID:11487055

chr10

Promoter: 131153956 - 131155956PMID:15455350

chr10

Promoter: 131153956 - 131155956PMID:16051033

chr10

Promoter: 131153956 - 131155956PMID:16391867

chr10

Promoter: 131153956 - 131155956PMID:12503076

chr10

Promoter: 131153956 - 131155956PMID:12826052

chr10

Promoter: 131153956 - 131155956PMID:15526363

chr10

Promoter: 131153956 - 131155956PMID:16174854

chr10

Promoter: 131153956 - 131155956PMID:15386372

chr10

Promoter: 131153956 - 131155956PMID:17339237

chr10

Promoter: 131153956 - 131155956PMID:15760919

chr10

Promoter: 131153956 - 131155956PMID:17183069

chr10

Promoter: 131153956 - 131155956PMID:15122305

chr10

Promoter: 131153956 - 131155956PMID:10811111

chr10

Promoter: 131153956 - 131155956PMID:11406538

chr10

Promoter: 131153956 - 131155956PMID:12000733

chr10

Promoter: 131153956 - 131155956PMID:15389252

chr10

Promoter: 131153956 - 131155956PMID:10078936

chr10

Promoter: 131153956 - 131155956PMID:17372756

chr10

Promoter: 131153956 - 131155956PMID:16436636

chr10

Promoter: 131153956 - 131155956PMID:11221863

chr10

Promoter: 131153956 - 131155956PMID:15800999

chr10

Promoter: 131153956 - 131155956PMID:16902913

chr10

Promoter: 131153956 - 131155956PMID:17378912

chr10

Promoter: 131153956 - 131155956PMID:17276933

chr10

Promoter: 131153956 - 131155956PMID:16336454

chr10

Promoter: 131153956 - 131155956PMID:15476557

chr10

Promoter: 131153956 - 131155956PMID:12538473

chr10

Promoter: 131153956 - 131155956PMID:11719438

chr10

Promoter: 131153956 - 131155956PMID:11196170

chr10

Promoter: 131153956 - 131155956PMID:16870044

chr10

Promoter: 131153956 - 131155956PMID:12684406

chr10

Promoter: 131153956 - 131155956PMID:16043258

chr10

Promoter: 131153956 - 131155956PMID:15201980

chr10

Promoter: 131153956 - 131155956PMID:12467239

chr10

Promoter: 131153956 - 131155956PMID:11895880

chr10

Promoter: 131153956 - 131155956PMID:12941804

chr10

Promoter: 131153956 - 131155956PMID:12473584

chr10

Promoter: 131153956 - 131155956PMID:15639718

chr10

Promoter: 131153956 - 131155956PMID:14742312

chr10

Promoter: 131153956 - 131155956PMID:15943786

chr10

Promoter: 131153956 - 131155956PMID:15073103

chr10

Promoter: 131153956 - 131155956PMID:11956078

chr10

Promoter: 131153956 - 131155956PMID:15758578

chr10

Promoter: 131153956 - 131155956PMID:11519041

chr10

Promoter: 131153956 - 131155956PMID:12695555

chr10

Promoter: 131153956 - 131155956PMID:14556664

chr10

Promoter: 131153956 - 131155956PMID:12746473

chr10

Promoter: 131153956 - 131155956PMID:15616773

chr10

Promoter: 131153956 - 131155956PMID:12763209

chr10

Promoter: 131153956 - 131155956PMID:16108828

chr10

Promoter: 131153956 - 131155956PMID:16475210

chr10

Promoter: 131153956 - 131155956PMID:11872960

chr10

Promoter: 131153956 - 131155956PMID:14507661

chr10

Promoter: 131153956 - 131155956PMID:15831994

chr10

Promoter: 131153956 - 131155956PMID:17369979

chr10

Promoter: 131153956 - 131155956PMID:11753949

chr10

Promoter: 131153956 - 131155956PMID:17139167

chr10

Promoter: 131153956 - 131155956PMID:14675710

chr10

Promoter: 131153956 - 131155956PMID:15589597

chr10

Promoter: 131153956 - 131155956PMID:11448914

chr10

Promoter: 131153956 - 131155956PMID:15785933

chr10

Promoter: 131153956 - 131155956PMID:16928264

chr10

Promoter: 131153956 - 131155956PMID:15099958

chr10

Promoter: 131153956 - 131155956PMID:12773202

chr10

Promoter: 131153956 - 131155956PMID:15713962

chr10

Promoter: 131153956 - 131155956PMID:16477636

chr10

Promoter: 131153956 - 131155956PMID:15870861

chr10

Promoter: 131153956 - 131155956PMID:12807758

chr10

Promoter: 131153956 - 131155956PMID:15703815

chr10

Promoter: 131153956 - 131155956PMID:16685400

chr10

Promoter: 131153956 - 131155956PMID:11309301

chr10

Promoter: 131153956 - 131155956PMID:15217927

chr10

Promoter: 131153956 - 131155956PMID:14555992

chr10

Promoter: 131153956 - 131155956PMID:15289362

chr10

Promoter: 131153956 - 131155956PMID:12660028

chr10

Promoter: 131153956 - 131155956PMID:16858686

chr10

Promoter: 131153956 - 131155956PMID:11773279

chr10

Promoter: 131153956 - 131155956PMID:14743506

chr10

Promoter: 131153956 - 131155956PMID:15623627

chr10

Promoter: 131153956 - 131155956PMID:12845678

chr10

Promoter: 131153956 - 131155956PMID:16170165

chr10

Promoter: 131153956 - 131155956PMID:17363525

chr10

Promoter: 131153956 - 131155956PMID:12149142

chr10

Promoter: 131153956 - 131155956PMID:16889486

chr10

Promoter: 131153956 - 131155956PMID:12584167

chr10

Promoter: 131153956 - 131155956PMID:16537562

chr10

Promoter: 131153956 - 131155956PMID:16258509

chr10

Promoter: 131153956 - 131155956PMID:14501508

chr10

Promoter: 131153956 - 131155956PMID:15184253

chr10

Promoter: 131153956 - 131155956PMID:15173091

chr10

Promoter: 131153956 - 131155956PMID:15635575

chr10

Promoter: 131153956 - 131155956PMID:11221887

chr10

Promoter: 131153956 - 131155956PMID:12124340

chr10

Promoter: 131153956 - 131155956PMID:16849682

chr10

Promoter: 131153956 - 131155956PMID:15154012

chr10

Promoter: 131153956 - 131155956PMID:11839665

chr10

Promoter: 131153956 - 131155956PMID:16764763

chr10

Promoter: 131153956 - 131155956PMID:12478658

chr10

Promoter: 131153956 - 131155956PMID:15467712

chr10

Promoter: 131153956 - 131155956PMID:12213730

chr10

Promoter: 131153956 - 131155956PMID:15975525

chr10

Promoter: 131153956 - 131155956PMID:12672028

chr10

Promoter: 131153956 - 131155956PMID:16791592

chr10

Promoter: 131153956 - 131155956PMID:15254699

chr10

Promoter: 131153956 - 131155956PMID:14970867

chr10

Promoter: 131153956 - 131155956PMID:16740754

chr10

Promoter: 131153956 - 131155956PMID:16061849

chr10

Promoter: 131153956 - 131155956PMID:16303245

chr10

Promoter: 131153956 - 131155956PMID:16374457

chr10

Promoter: 131153956 - 131155956PMID:15064737

chr10

Promoter: 131153956 - 131155956PMID:17034532

chr10

Promoter: 131153956 - 131155956PMID:15172987

chr10

Promoter: 131153956 - 131155956PMID:16867861

chr10

Promoter: 131153956 - 131155956PMID:12942643

chr10

Promoter: 131153956 - 131155956PMID:16166431

chr10

Promoter: 131153956 - 131155956PMID:16711019

chr10

Promoter: 131153956 - 131155956PMID:15283294

chr10

Promoter: 131153956 - 131155956PMID:15695118

chr10

Promoter: 131153956 - 131155956PMID:15959912

chr10

Promoter: 131153956 - 131155956PMID:12082624

chr10

Promoter: 131153956 - 131155956PMID:15201966

chr10

Promoter: 131153956 - 131155956PMID:12730870

chr10

Promoter: 131153956 - 131155956PMID:15915369

chr10

Promoter: 131153956 - 131155956PMID:16258501

chr10

Promoter: 131153956 - 131155956PMID:14527906

chr10

Promoter: 131153956 - 131155956PMID:12632081

chr10

Promoter: 131153956 - 131155956PMID:15197802

chr10

Promoter: 131153956 - 131155956PMID:12545168


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