| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4204 |
Name | MECP2 |
Synonymous | AUTSX3|MRX16|MRX79|MRXS13|MRXSL|PPMX|RS|RTS|RTT;methyl CpG binding protein 2 (Rett syndrome);MECP2;methyl CpG binding protein 2 (Rett syndrome) |
Definition | meCp-2 protein|methyl-CpG-binding protein 2 |
Position | Xq28 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | MECP-2(h) + sin3a(h) <==> MECP-2(h):sin3a(h) (binding) | HDAC1(h) + MECP-2(h) <==> HDAC1(h):MECP-2(h) (binding) | hdac2(h) + MECP-2(h) <==> hdac2(h):MECP-2(h) (binding) | MECP2(h) --> MECP-2(h) (expression). | SMRT(x) + MECP-2(h) + Sin3(x) <==> SMRT(x):MECP-2(h):Sin3(x) (binding) | MECP-2(h) --> Dlx-6(m) (DNA binding). | MECP-2(h) --> BDNF(m) (DNA binding). | MECP2(h) --> MECP-2(h) (expression). | MECP2(h) --> MECP2(h) (expression). | hsa-miR-130a --/ MECP2(h) (predicted) | hsa-miR-130b --/ MECP2(h) (predicted) | hsa-miR-19a --/ MECP2(h) (predicted) |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 80 | Phosphoserine. | Swiss-Prot 53.0 | 229 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 423 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 80 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 166 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chrX |
Promoter: 153015823 - 153017823 | Agilent_014791 |
chrX |
Promoter: 153015823 - 153017823 | GoldenGate_Methylation_Cancer_Panel_I |
chrX |
Promoter: 153015823 - 153017823 | GSE27584 |
chrX |
Promoter: 153015823 - 153017823 | Agilent_014791_44K |