Entrez Gene

Basic Information
Gene ID	4192
Name	MDK
Synonymous	MK\|NEGF2;midkine (neurite growth-promoting factor 2);MDK;midkine (neurite growth-promoting factor 2)
Definition	ARAP\|amphiregulin-associated protein\|midgestation and kidney protein\|midkine\|neurite outgrowth-promoting factor 2\|neurite outgrowth-promoting protein
Position	11p11.2
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
beta1-integrin(m) + MK(h) <==> beta1-integrin(m):MK(h) (binding)
alpha4-integrin(h) + MK(h) <==> alpha4-integrin(h):MK(h) (binding)
alpha6-integrin(h) + MK(h) <==> alpha6-integrin(h):MK(h) (binding)
beta1-integrin(h) + MK(h) <==> beta1-integrin(h):MK(h) (binding)
beta1-integrin(h):alpha4-integrin(mo) + MK(h) <==> beta1-integrin(h):alpha4-integrin(mo):MK(h) (binding)
alpha6-integrin(mo):beta1-integrin(h) + MK(h) <==> MK(h):beta1-integrin(h):alpha6-integrin(mo) (binding)
MK(h) --> paxillin(r){pY} (increase of phosphorylation)
MK(h) --> Jak1(h){pY} (increase of phosphorylation)
MK(h) --> Jak2(h){pY} (increase of phosphorylation)
MK(h) --> STAT1alpha(h){pY} (increase of phosphorylation)
MDK(h) --> MK(h) (expression).
MDK(h) --> MK(h) (expression).

Post Translational Modification [Top]
	There is no record for MDK

Transcription Factors [Top]