| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4155 |
Name | MBP |
Synonymous | -;myelin basic protein;MBP;myelin basic protein |
Definition | myelin A1 protein|myelin membrane encephalitogenic protein |
Position | 18q23 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | MBP(h) --> MBP(h) (expression). | MBP(h) --> MBP-Isoform5(h) (expression). | MBP(h) --> MBP-Isoform1(h) (expression). | MBP(h) --> MBP-Isoform2(h) (expression). | MBP(h) --> MBP-Isoform3(h) (expression). | MBP(h) --> MBP-Isoform4(h) (expression). | MBP(h) --> MBP-Isoform6(h) (expression). | MBP(h) --> MBP-Isoform7(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 96 | Phosphoserine. | Swiss-Prot 53.0 | 141 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 146 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 159 | Citrulline; in form C8. | Swiss-Prot 53.0 | 165 | Citrulline; in form C8. | Swiss-Prot 53.0 | 169 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 174 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 205 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 229 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 232 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 237 | Deamidated glutamine (By similarity). | Swiss-Prot 53.0 | 241 | Omega-N-methylarginine; alternate. | Swiss-Prot 53.0 | 241 | Symmetric dimethylarginine; alternate. | Swiss-Prot 53.0 | 249 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 256 | Citrulline; in form C8. | Swiss-Prot 53.0 | 264 | Citrulline; in form C8. | Swiss-Prot 53.0 | 281 | Deamidated glutamine (By similarity). | Swiss-Prot 53.0 | 293 | Citrulline; in form C8. | Swiss-Prot 53.0 | 295 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 299 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 304 | Citrulline; in form C8. | Swiss-Prot 53.0 | 299 | Phosphoserine (KIS) | 10880969 | Phospho.ELM 6.0 | 232 | Phosphothreonine (MAPK1;MAPK3) | 1939237 | Phospho.ELM 6.0 | 96 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 121 | O-linked | Persaud R., Fraser P., Wood DD., and Moscarello MA. (1988)Biochim Biophys Acta, 966, 357-61. Medline: 88327009; | OGlycBase6.0 | 124 | O-linked | Persaud R., Fraser P., Wood DD., and Moscarello MA. (1988)Biochim Biophys Acta, 966, 357-61. Medline: 88327009; | OGlycBase6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr18 |
Promoter: 72973262 - 72975262 | Agilent_014791 |
chr18 |
Promoter: 72857543 - 72859543 | GSE27584 |
chr18 |
Promoter: 72857543 - 72859543 | GSE27584 |
chr18 |
Promoter: 72857543 - 72859543 | GSE27584 |
chr18 |
Promoter: 72973262 - 72975262 | GSE27584 |
chr18 |
Promoter: 72973262 - 72975262 | GSE27584 |
chr18 |
Promoter: 72857543 - 72859543 | GSE27584 |
chr18 |
Promoter: 72973262 - 72975262 | Agilent_014791_44K |