| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 4133 |
Name | MAP2 |
Synonymous | MAP2A|MAP2B|MAP2C;microtubule-associated protein 2;MAP2;microtubule-associated protein 2 |
Definition | MAP-2 |
Position | 2q34-q35 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Grb-2(h) + MAP-2(h) <==> Grb-2(h):MAP-2(h) (binding) | MAP2(h) --> MAP-2(h) (expression). | Grb-2(m.s.) + MAP-2b(h) <==> Grb-2(m.s.):MAP-2b(h) (binding) | MAP2(h) --> MAP-2b(h) (expression). | Map-2c(h) + ATP --Fyn(h)--> Map-2c(h){pY67} + ADP (phosphorylation) | Map-2c(h) --> protein remnants (degradation) | Map-2c(h) + Grb-2(m.s.) <==> Map-2c(h):Grb-2(m.s.) (binding) | Fyn(m.s.) + Map-2c(h) <==> Fyn(m.s.):Map-2c(h) (binding) | Src(m.s.) + Map-2c(h) <==> Src(m.s.):Map-2c(h) (binding) | Fyn(h) + Map-2c(h) <==> Fyn(h):Map-2c(h) (binding) | Map-2c(h) + 2 ATP --ERK2(h)--> Map-2c(h){pT293}{pS297} + 2 ADP (phosphorylation) | Map-2c(h) + ATP --> Map-2c(h){pT293} + ADP (phosphorylation) | Map-2c(h) + ATP --Fyn(m.s.)--> Map-2c(h){pY} + ADP (phosphorylation) | Map-2c(h) + ATP --Fyn(h)--> Map-2c(h){pY} + ADP (phosphorylation) | MAP2(h) --> Map-2c(h) (expression). | MAP2(h) --> Map-2-isoform3(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 610 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 629 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 654 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 729 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 736 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 745 | Phosphotyrosine (By similarity). | Swiss-Prot 53.0 | 821 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 833 | Phosphoserine. | Swiss-Prot 53.0 | 1155 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1347 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1353 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1421 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1440 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 1480 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1534 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1591 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1594 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 1595 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 1602 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 1605 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 1608 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1611 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1613 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 1616 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 1649 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 1782 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1790 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1798 | Phosphoserine. | Swiss-Prot 53.0 | 1799 | Phosphoserine. | Swiss-Prot 53.0 | 1800 | Phosphoserine. | Swiss-Prot 53.0 | 1802 | Phosphoserine. | Swiss-Prot 53.0 | 67 | Phosphotyrosine (Fyn;Lyn) | 15536091 | Phospho.ELM 6.0 | 833 | Phosphoserine | 15822905 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr2 |
Promoter: 210151148 - 210153148 | GSE27584 |
chr2 |
Promoter: 210151148 - 210153148 | GSE27584 |
chr2 |
Promoter: 209995516 - 209997516 | GSE27584 |
chr2 |
Promoter: 210151148 - 210153148 | GSE27584 |