Entrez Gene

Basic Information
Gene ID	3953
Name	LEPR
Synonymous	CD295\|LEP-R\|OB-R\|OBR;leptin receptor;LEPR;leptin receptor
Definition	OB receptor\|huB219
Position	1p31
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
2 lepr-B(h) <==> (lepr-B(h))2 (oligomerization)
lepr-B(h) + ATP --> lepr-B(h){pY} + ADP (phosphorylation)
leptin(m.s.) + lepr-B(h) <==> leptin(m.s.):lepr-B(h) (binding)
LEPR(h) --> lepr-B(h) (expression).
leptin(h) + lepr(h) <==> leptin(h):lepr(h) (binding)
lepr(h) --> lepr(h) (expression).
lepr(h){gly} --> lepr(h) + NDP-Gly (deglycosylation)
leptin(m.s.) + lepr-A(h) <==> leptin(m.s.):lepr-A(h) (binding)
LEPR(h) --> lepr-A(h) (expression).
leptin(m.s.) + lepr-C(h) <==> leptin(m.s.):lepr-C(h) (binding)
LEPR(h) --> lepr-C(h) (expression).
leptin(m.s.) + lepr-D(h) <==> leptin(m.s.):lepr-D(h) (binding)
LEPR(h) --> lepr-D(h) (expression).
leptin(h) + lepr-E(h) <==> leptin(h):lepr-E(h) (binding)
LEPR(h) --> lepr-E(h) (expression).
lepr-E(h){gly} --> lepr-E(h) + NDP-Gly (deglycosylation)

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
23	N-linked (GlcNAc...).		Swiss-Prot 53.0
41	N-linked (GlcNAc...).		Swiss-Prot 53.0
56	N-linked (GlcNAc...).		Swiss-Prot 53.0
73	N-linked (GlcNAc...).		Swiss-Prot 53.0
81	N-linked (GlcNAc...).		Swiss-Prot 53.0
98	N-linked (GlcNAc...).		Swiss-Prot 53.0
187	N-linked (GlcNAc...).		Swiss-Prot 53.0
206	N-linked (GlcNAc...).		Swiss-Prot 53.0
276	N-linked (GlcNAc...).		Swiss-Prot 53.0
347	N-linked (GlcNAc...).		Swiss-Prot 53.0
397	N-linked (GlcNAc...).		Swiss-Prot 53.0
516	N-linked (GlcNAc...).		Swiss-Prot 53.0
624	N-linked (GlcNAc...).		Swiss-Prot 53.0
659	N-linked (GlcNAc...).		Swiss-Prot 53.0
688	N-linked (GlcNAc...).		Swiss-Prot 53.0
697	N-linked (GlcNAc...).		Swiss-Prot 53.0
728	N-linked (GlcNAc...).		Swiss-Prot 53.0
750	N-linked (GlcNAc...).		Swiss-Prot 53.0
986	Phosphotyrosine (by JAK2) (Bysimilarity).		Swiss-Prot 53.0
1141	Phosphotyrosine (by JAK2) (Bysimilarity).		Swiss-Prot 53.0
1141	Phosphotyrosine	14625304	Phospho.ELM 6.0

Transcription Factors [Top]