| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 3856 |
Name | KRT8 |
Synonymous | CARD2|CK-8|CK8|CYK8|K2C8|K8|KO;keratin 8;KRT8;keratin 8 |
Definition | cytokeratin 8|cytokeratin-8|keratin, type II cytoskeletal 8|type-II keratin Kb8 |
Position | 12q13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | DEDD(h) + Keratin-8(h) <==> DEDD(h):Keratin-8(h) (binding) | Keratin-8(h) + APG1(h) <==> Keratin-8(h):APG1(h) (binding) | Keratin-8(h) + NCL(h) <==> Keratin-8(h):NCL(h) (binding) | Keratin-8(h) + ATP --> Keratin-8(h){p} + ADP (phosphorylation) | Keratin-8(h) + n ATP --> Keratin-8(h){p}n + n ADP (phosphorylation) | Keratin-18(h) + Keratin-8(h) <==> Keratin-18(h):Keratin-8(h) (binding) | Keratin-8(h) + ATP --> Keratin-8(h){pS74} + ADP (phosphorylation) | Keratin-8(h) + ATP --p38(m.s.)--> Keratin-8(h){pS74} + ADP (phosphorylation) | Keratin-8(h) + ATP --ERK2(m.s.)--> Keratin-8(h){pS74} + ADP (phosphorylation) | Keratin-8(h) + ATP --JNK(m.s.)--> Keratin-8(h){pS74} + ADP (phosphorylation) | Keratin-8(h) + p38alpha(h) <==> Keratin-8(h):p38alpha(h) (binding) | Keratin-8(h) + p38(m.s.) <==> Keratin-8(h):p38(m.s.) (binding) | KRT8(h) --> Keratin-8(h) (expression). | Periplakin(h) + Keratin-8(h) <==> Periplakin(h):Keratin-8(h) (binding) | Keratin-8(h) + Pinin(h) <==> Keratin-8(h):Pinin(h) (binding) | Keratin-8(h) + Dystrophin-4(h) <==> Keratin-8(h):Dystrophin-4(h) (binding) | KRT8(h) --> Keratin-8(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 9 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 13 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 21 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 22 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 24 | Phosphoserine. | Swiss-Prot 53.0 | 26 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 27 | Phosphoserine. | Swiss-Prot 53.0 | 34 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 37 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 43 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 44 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 74 | Phosphoserine (by MAPK). | Swiss-Prot 53.0 | 253 | Phosphoserine. | Swiss-Prot 53.0 | 330 | Phosphoserine. | Swiss-Prot 53.0 | 417 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 424 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 432 | Phosphoserine (by CaMK2 and MAPK). | Swiss-Prot 53.0 | 451 | Phosphoserine. | Swiss-Prot 53.0 | 475 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 478 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 431 | Phosphoserine (CDK1;MAPK3;M) | 97207326;9524113;9054461 | Phospho.ELM 6.0 | 23 | Phosphoserine | 97207326;16083285 | Phospho.ELM 6.0 | 20 | Phosphoserine | 16083285 | Phospho.ELM 6.0 | 21 | Phosphoserine | 16083285 | Phospho.ELM 6.0 | 36 | Phosphoserine | 16083285;17081983 | Phospho.ELM 6.0 | 42 | Phosphoserine | 16083285;17081983 | Phospho.ELM 6.0 | 73 | Phosphoserine (MAP2K1;MAP2K) | 11788583;15972820;11781324 | Phospho.ELM 6.0 | 450 | Phosphoserine | 16565220 | Phospho.ELM 6.0 | 33 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 252 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 329 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 474 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for KRT8 | ||