| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 367 |
Name | AR |
Synonymous | AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM;androgen receptor;AR;androgen receptor |
Definition | androgen nuclear receptor variant 2|dihydrotestosterone receptor|nuclear receptor subfamily 3 group C member 4 |
Position | Xq12 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | estradiol:ER-beta-isoform1(h) + AR(h) + Src(h) <==> estradiol:ER-beta-isoform1(h):AR(h):Src(h) (binding) | estradiol:ER-alpha(h) + AR(h) + Src(h) <==> estradiol:ER-alpha(h):AR(h):Src(h) (binding) | AR(h) + STAT3(h) <==> AR(h):STAT3(h) (binding) | bag1-xbb1(h) + AR(h) <==> bag1-xbb1(h):AR(h) (binding) | AR(h) --> factor IX(h) (DNA binding). | ZAC-1b(m) + AR(h) <==> ZAC-1b(m):AR(h) (binding) | 2 AR(h) <==> (AR(h))2 (binding) | AR(h) --> CDKN1A(h) (DNA binding; transactivation). | AR(h) --> Svs6(m) (DNA binding; transactivation). | AR(h) --> Akr1b7(m) (DNA binding; transactivation). | AR(h) --Caspase-3(h)--> AR-p18(h) + AR-p47(h) + AR-p60(h) + AR-p87(h) (processing) | AR(h) + FOXO1A(h) <==> AR(h):FOXO1A(h) (binding) | TIF2(m) + AR(h) <==> TIF2(m):AR(h) (binding) | AR(h) + MRF1(h) <==> AR(h):MRF1(h) (binding) | Hic-5(m.s.) + AR(h) <==> Hic-5(m.s.):AR(h) (binding) | ARA54(m.s.) + AR(h) <==> ARA54(m.s.):AR(h) (binding) | AR(h) + SVIL(h) <==> AR(h):SVIL(h) (binding) | AR(h) + acetyl-CoA --p300(h)--> AR(h){aceK} + CoA (acetylation) | AR(h) + 3 acetyl-CoA --p300(m.s.)--> AR(h){aceK630}{aceK632}{aceK633} + 3 CoA (acetylation) | AR(h) + p300(m.s.) <==> AR(h):p300(m.s.) (binding) | AR(h) + p85alpha(m.s.) <==> AR(h):p85alpha(m.s.) (binding) | AR(h) + HIPK3(m.s.) <==> AR(h):HIPK3(m.s.) (binding) | SRC-1(h) + AR(h) <==> AR(h):SRC-1(h) (binding) | ARA70(h) + AR(h) <==> AR(h):ARA70(h) (binding) | AR(h) + SMRT(m.s.) <==> SMRT(m.s.):AR(h) (binding) | AR(h) --> ERK1(h){pT202} (increase of phosphorylation) | AR(h) --> ERK2(h){pT185}{pY187} (increase of phosphorylation) | AR(h) --> CREB1(h){pS133} (increase of phosphorylation) | AR(h) --> c-Fos(m) (increase of promoter activity) | AR(h) --> kallikrein-3(m.s.) (increase of promoter activity) | FKBP52(m.s.) + AR(h) <==> FKBP52(m.s.):AR(h) (binding) | AR(h) + ACTA-1(m) <==> AR(h):ACTA-1(m) (binding) | SRF(m.s.) + AR(h) <==> SRF(m.s.):AR(h) (binding) | AR(h) + SRF(m.s.) <==> SRF(m.s.):AR(h) (binding) | AR(h) --> CFLAR(h) (DNA binding) | AR(h) --> ER-alpha(h) (activation) | AR(h) --> ER-beta(h) (activation) | AR(h) + CHIP(m.s.) <==> AR(h):CHIP(m.s.) (binding) | AR(h) + CHIP(h) <==> AR(h):CHIP(h) (binding) | AR(h) + ubiquitin(v.s.) --CHIP(m.s.)--> AR(h){ub} (stabilization; ubiquitination) | AR(h) + mdm2(h) <==> AR(h):mdm2(h) (binding) | RAI17(m) + AR(h) <==> RAI17(m):AR(h) (binding) | RAI17(h) + AR(h) <==> RAI17(h):AR(h) (binding) | AR(h) --> C4a(m) (DNA binding). | GAPD(rb) + AR(h) <==> GAPD(rb):AR(h) (binding) | AR(h) + ARA70-alpha(h) <==> AR(h):ARA70-alpha(h) (binding) | TIF1a-short(h) + AR(h) <==> TIF1a-short(h):AR(h) (binding) | AR(h) + mdm2(h) + AKT-1(h) <==> AR(h):mdm2(h):AKT-1(h) (binding) | AR(h) + ATP --> AR(h){pS213} + ADP (phosphorylation) | AR(h) + Src(h) + MNAR-isoform2(h) <==> AR(h):Src(h):MNAR-isoform2(h) (binding) | AR(h) --> AR(h) (translocation) | AR(h) + AKT-1(h) <==> AR(h):AKT-1(h) (binding) | AR(h) + ATP --> AR(h){p} + ADP (phosphorylation) | AR(h) + ubiquitin(h) --> AR(h){ub} (ubiquitination) | AR(h) + mdm2(h) + HDAC1(h) <==> AR(h):mdm2(h):HDAC1(h) (binding) | SRC3(h) + AR(h) <==> SRC3(h):AR(h) (binding) | AR(h) + PIRH2(h) <==> AR(h):PIRH2(h) (binding) | AR(h) + HOXB13(h) <==> AR(h):HOXB13(h) (binding) | AR(h) + ATP --p38(h)--> AR(h){pS650} + ADP (phosphorylation) | AR(h) + ATP --JNK(h)--> AR(h){pS650} + ADP (phosphorylation) | AR(h) --> KLK3(h) (transactivation) | AR(h) + acetyl-CoA --p300(m.s.)--> AR(h){aceK} + CoA (acetylation) | AR(h) + C/EBPalpha(h) <==> AR(h):C/EBPalpha(h) (binding) | AR(h) --> AR(h) (translocation) | Hsp90(h) + AR(h) <==> Hsp90(h):AR(h) (binding) | cyclinD1b(h) + AR(h) <==> cyclinD1b(h):AR(h) (binding) | Daxx(h) + AR(h) <==> Daxx(h):AR(h) (binding) | AR(h) --> AR(h) (translocation) | PARP(h) + AR(h) <==> PARP(h):AR(h) (binding) | TopoI(h) + AR(h) <==> TopoI(h):AR(h) (binding) | Grp94(h) + AR(h) <==> Grp94(h):AR(h) (binding) | Hsp90-alpha(h) + AR(h) <==> Hsp90-alpha(h):AR(h) (binding) | GRP78(h) + AR(h) <==> GRP78(h):AR(h) (binding) | Hsc70(h) + AR(h) <==> Hsc70(h):AR(h) (binding) | Ku70(h) + AR(h) <==> Ku70(h):AR(h) (binding) | Hsp70-1(h) + AR(h) <==> Hsp70-1(h):AR(h) (binding) | DNA-PKcs(h) + Ku80(h) + Ku70(h) + AR(h) <==> DNA-PKcs(h):Ku80(h):Ku70(h):AR(h) (binding) | MAK(h) + AR(h) <==> MAK(h):AR(h) (binding) | DAX1(h) + AR(h) <==> DAX1(h):AR(h) (binding) | BAF57(h) + AR(h) <==> BAF57(h):AR(h) (binding) | HDAC1(h) + AR(h) <==> HDAC1(h):AR(h) (binding) | Egr-1(h) + AR(h) <==> Egr-1(h):AR(h) (binding) | AR(h) --> NKX3-1(h) (transactivation) | AR(h) --> B2M(h) (transactivation) | NCOR1(h) + AR(h) <==> NCOR1(h):AR(h) (binding) | SMRT(h) + AR(h) <==> SMRT(h):AR(h) (binding) | Tip60(h) + HDAC1(h) + AR(h) <==> Tip60(h):HDAC1(h):AR(h) (binding) | AR(h) + ATP --> AR(h){pS} + ADP (phosphorylation) | AR(h) + acetyl-CoA --> AR(h){aceK} + CoA (acetylation) | SIRT1(h) + AR(h) <==> SIRT1(h):AR(h) (binding) | Hip-1(h) + AR(h) <==> Hip-1(h):AR(h) (binding) | AR(h) + ATP --> AR(h){pS81} + ADP (phosphorylation) | MNAR(h) + AR(h) <==> MNAR(h):AR(h) (binding) | AR(h) + ARA54(h) <==> AR(h):ARA54(h) (binding) | DRIP205(h) + AR(h) <==> DRIP205(h):AR(h) (binding) | AR(h) --> AR-p50(h) + protein remnants (cleavage) | AR(h) --> AR-p34(h) + protein remnants (cleavage) | calmodulin(m.s.) + AR(h) <==> calmodulin(m.s.):AR(h) (binding) | calpastatin(h) + calmodulin(h) + calpain(h) + AR(h) <==> calpastatin(h):calmodulin(h):calpain(h):AR(h) (binding) | Hey1(m.s.) + AR(h) <==> Hey1(m.s.):AR(h) (binding) | Hey1(h) + AR(h) <==> Hey1(h):AR(h) (binding) | AR(h) --> KLK2(h) (transactivation) | AR(h) + PAK6(h) <==> AR(h):PAK6(h) (binding) | TIF2(m.s.) + AR(h) <==> TIF2(m.s.):AR(h) (binding) | ACK-1(m.s.) + AR(h) <==> ACK-1(m.s.):AR(h) (binding) | AR(h) + ATP --> AR(h){pY} + ADP (phosphorylation) | AR(h) + TIF2(h) <==> AR(h):TIF2(h) (binding) | AR(h) + POB1(h) <==> AR(h):POB1(h) (binding) | AR(h) + ATSV(h) <==> AR(h):ATSV(h) (binding) | AR(h) + gelsolin(h) <==> AR(h):gelsolin(h) (binding) | AR(h) --> Scgb2a2(r) (DNA binding). | AR(h) --> atad2(h) (increase of abundance) | AR(h) + atad2(h) <==> AR(h):atad2(h) (binding) | AR(h) + NSD2(m.s.) <==> AR(h):NSD2(m.s.) (binding) | AR(h) --> IGFBP3(h) (DNA binding). | AR(h) --> MMP2(h) (DNA binding). | AR(h) --> PIGR(h) (DNA binding). | AR(h) --> CCND1(h) (DNA binding). | AR(h) --> F2R(h) (DNA binding). | AR(h) --> ELK4(h) (DNA binding). | AR(h) --> SERPINB5(h) (DNA binding). | AR(h) --> Ceacam1(r) (DNA binding; transactivation). | AR(h) --> AR(h) (expression). | TIF2(m.s.) --> AR(h) (activation) | SRC-1(m.s.) --> AR(h) (activation) | p300(m.s.) --> AR(h) (activation) | p/CAF(m.s.) --> AR(h) (activation) | ARA54(m.s.) --> AR(h) (activation) | ARA70(m.s.) --> AR(h) (activation) | gelsolin(m.s.) --> AR(h) (activation) | BAG-1L(m.s.) --> AR(h) (activation) | caveolin-1(m.s.) --> AR(h) (activation) | beta-catenin(h) --> AR(h) (activation) | ABP-280(m.s.) --> AR(h) (regulation of localization) | ABP-280(m.s.) --> AR(h) (regulation of protein activity) | Src(h) --> AR(h) (binding) | NRG1(m.s.) --> AR(h) (activation) | Grp(m.s.) --> AR(h) (activation) | Wnt-3A(m.s.) --> AR(h) (activation) | ER-beta(h) --> AR(h) (binding) | ER-alpha(h) --> AR(h) (binding) | ER-alpha(h) --> AR(h) (activation) | ER-beta(h) --> AR(h) (activation) | ER-alpha(m.s.) --> AR(h) (binding) | ER-beta(m.s.) --> AR(h) (binding) | MO15(h) --> AR(h) (binding) | SNURF(m.s.) --> AR(h) (binding) | CHIP(m.s.) --> AR(h) (decrease of abundance) | IGF-1(m.s.) --> AR(h) (decrease of abundance) | Cdk6(m.s.) --> AR(h) (increase of abundance) | AR(h) --> AR(h) (translocation) | AR(h) --> AR(h) (translocation) | AR(h) --> AR(h) (translocation) | FOXO3a(m.s.) --> AR(h) (increase of abundance) | 5alphaDHT --> AR(h) (increase of abundance) | AR-isoform1(h) --> CRISP1(m) (DNA binding). | AR-isoform1(h) --> CRISP3(m) (DNA binding). | AR-isoform1(h) --> PIGR(h) (DNA binding; transactivation). | AR-isoform1(h) --> C4a(m) (DNA binding; transactivation). | AR-isoform1(h) --> KLK3(h) (DNA binding; transactivation). | AR-isoform1(h) --> Rhox5(m) (DNA binding; transregulation). | AR-isoform1(h) --> AR(h) (DNA binding; transactivation). | AR-isoform1(h) --> P22K15(r) (DNA binding; transactivation). | AR-isoform1(h) --> Kap(m) (DNA binding). | 14-3-3eta(h) + AR-isoform1(h) <==> 14-3-3eta(h):AR-isoform1(h) (binding) | AR-isoform1(h) + DAP3(h) <==> AR-isoform1(h):DAP3(h) (binding) | AR-isoform1(h) + CHIP(h) <==> AR-isoform1(h):CHIP(h) (binding) | AR-isoform1(h) + mdm2-isoform1(h) <==> AR-isoform1(h):mdm2-isoform1(h) (binding) | AR-isoform1(h) + n ubiquitin(h) --mdm2(h)--> AR-isoform1(h){ub(n)} (ubiquitination) | AR-isoform1(h) + ATP --> AR-isoform1(h){pS213} + ADP (phosphorylation) | AR-isoform1(h) --> AR-isoform1(h) (translocation) | AR-isoform1(h) + ATP --AKT-1(m.s.)--> AR-isoform1(h){pS213}{pS791} + ADP (phosphorylation) | AR-isoform1(h) + ATP --AKT-1(h)--> AR-isoform1(h){p} + ADP (phosphorylation) | AR-isoform1(h) + ATP --AKT-1(h)--> AR-isoform1(h){pS213}{pS791} + ADP (phosphorylation) | AR-isoform1(h) + ARA70-alpha(h) <==> AR-isoform1(h):ARA70-alpha(h) (binding) | AR-isoform1(h) + mdm2-isoform1(h) --26S proteasome(h)--> mdm2-isoform1(h) + protein remnants (degradation) | AR-isoform1(h) + ubiquitin(h) --mdm2(m.s.)--> AR-isoform1(h){ub} (ubiquitination) | AR-isoform1(h) --> AR-isoform1(h) (translocation) | AR-isoform1(h) + ATP --> AR-isoform1(h){pS81} + ADP (phosphorylation) | Hic-5(m.s.) + AR-isoform1(h) <==> Hic-5(m.s.):AR-isoform1(h) (binding) | ARA54(m.s.) + AR-isoform1(h) <==> ARA54(m.s.):AR-isoform1(h) (binding) | p/CAF(m.s.) + AR-isoform1(h) <==> p/CAF(m.s.):AR-isoform1(h) (binding) | AR-isoform1(h) + PIASy(h) <==> AR-isoform1(h):PIASy(h) (binding) | AR-isoform1(h) + GAC63(m) <==> AR-isoform1(h):GAC63(m) (binding) | USP10(h) + AR-isoform1(h) <==> USP10(h):AR-isoform1(h) (binding) | AR-isoform1(h) --> Rhox5(m) (transactivation) | ARIP4(m) + AR-isoform1(h) <==> ARIP4(m):AR-isoform1(h) (binding) | PIRH2(h) + AR-isoform1(h) <==> PIRH2(h):AR-isoform1(h) (binding) | AR-isoform1(h) + ATP --p38alpha(m.s.){p}--> AR-isoform1(h){pS650} + ADP (phosphorylation) | AR-isoform1(h) + ATP --JNK1(m.s.){p}--> AR-isoform1(h){pS650} + ADP (phosphorylation) | CBP(m.s.) + AR-isoform1(h) <==> CBP(m.s.):AR-isoform1(h) (binding) | AR-isoform1(h) + acetyl-CoA --p300(h)--> AR-isoform1(h){aceK630} + CoA (acetylation) | AR-isoform1(h) --> Pbsn(r) (transactivation) | AR-isoform1(h) + E6AP(m.s.) <==> AR-isoform1(h):E6AP(m.s.) (binding) | AR-isoform1(h) + ARA70-beta(h) <==> AR-isoform1(h):ARA70-beta(h) (binding) | BRG1(h) + AR-isoform1(h) <==> BRG1(h):AR-isoform1(h) (binding) | SRC3(h) + AR-isoform1(h) <==> SRC3(h):AR-isoform1(h) (binding) | SRC-1(h) + AR-isoform1(h) <==> SRC-1(h):AR-isoform1(h) (binding) | p300(h) + AR-isoform1(h) <==> p300(h):AR-isoform1(h) (binding) | AR-isoform1(h) + cyclinD1a(h) <==> AR-isoform1(h):cyclinD1a(h) (binding) | AR-isoform1(h) --> AR-isoform1(h) (translocation) | 2 AR-isoform1(h) <==> (AR-isoform1(h))2 (oligomerization) | NCOR1(h) + AR-isoform1(h) <==> NCOR1(h):AR-isoform1(h) (binding) | AR-isoform1(h) + Zimp7(h) <==> AR-isoform1(h):Zimp7(h) (binding) | Daxx(h) + AR-isoform1(h) <==> Daxx(h):AR-isoform1(h) (binding) | AR-isoform1(h) --> KLK3(h) (transactivation) | AR-isoform1(h) + sumo1(m.s.) --Aos1(m.s.):SAE2(m.s.),Ubc9(m.s.)--> AR-isoform1(h){sumo} (sumoylation) | p/CAF(h) + AR-isoform1(h) <==> p/CAF(h):AR-isoform1(h) (binding) | DNA-PKcs(h) + AR-isoform1(h) <==> DNA-PKcs(h):AR-isoform1(h) (binding) | Ku70(h) + AR-isoform1(h) <==> Ku70(h):AR-isoform1(h) (binding) | Ku80(h) + AR-isoform1(h) <==> Ku80(h):AR-isoform1(h) (binding) | PARP(h) + AR-isoform1(h) <==> PARP(h):AR-isoform1(h) (binding) | RPB1(h) + AR-isoform1(h) <==> RPB1(h):AR-isoform1(h) (binding) | TopoI(h) + AR-isoform1(h) <==> TopoI(h):AR-isoform1(h) (binding) | Ku70(m.s.) + AR-isoform1(h) <==> Ku70(m.s.):AR-isoform1(h) (binding) | Ku80(m.s.) + AR-isoform1(h) <==> Ku80(m.s.):AR-isoform1(h) (binding) | MAK(h) + AR-isoform1(h) <==> MAK(h):AR-isoform1(h) (binding) | SRC3(m.s.) + MAK(h) + AR-isoform1(h) <==> SRC3(m.s.):MAK(h):AR-isoform1(h) (binding) | AR-isoform1(h) + 2 sumo1(h) --> AR-isoform1(h){sumoK386}{sumoK520} (sumoylation) | AR-isoform1(h) + 2 sumo1(h) --> AR-isoform1(h){sumoK386}{sumoK520} (sumoylation) | AR-isoform1(h) + 2 sumo1(h) --Ubc9(m.s.)--> AR-isoform1(h){sumoK386}{sumoK520} (sumoylation) | AR-isoform1(h) + 2 sumo1(m.s.) --PIAS1(m.s.)--> AR-isoform1(h){sumoK386}{sumoK520} (sumoylation) | AR-isoform1(h) + 2 sumo1(m.s.) --PIAS2-alpha(m.s.)--> AR-isoform1(h){sumoK386}{sumoK520} (sumoylation) | AR-isoform1(h) + 2 sumo1(m.s.) --Aos1(h):SAE2(h),Ubc9(h),PIAS1(m.s.)--> AR-isoform1(h){sumoK386}{sumoK520} (sumoylation) | AR-isoform1(h) + 2 sumo1(m.s.) --Aos1(h):SAE2(h),Ubc9(h),PIAS2-alpha(m.s.)--> AR-isoform1(h){sumoK386}{sumoK520} (sumoylation) | AR-isoform1(h) + SRC-1A(h) <==> SRC-1A(h):AR-isoform1(h) (binding) | SMRT(m.s.) + AR-isoform1(h) <==> SMRT(m.s.):AR-isoform1(h) (binding) | ABP-280(h) + AR-isoform1(h) <==> ABP-280(h):AR-isoform1(h) (binding) | SRC-1A(m.s.) + AR-isoform1(h) <==> SRC-1A(m.s.):AR-isoform1(h) (binding) | TZF(m) + AR-isoform1(h) <==> TZF(m):AR-isoform1(h) (binding) | AR-isoform1(h) --> AR-isoform1(h) (translocation) | BAF57(h) + AR-isoform1(h) <==> BAF57(h):AR-isoform1(h) (binding) | TFIIF-alpha(m.s.) + AR-isoform1(h) <==> TFIIF-alpha(m.s.):AR-isoform1(h) (binding) | TFIIF-alpha(h) + AR-isoform1(h) <==> TFIIF-alpha(h):AR-isoform1(h) (binding) | TFIIF-beta(h) + AR-isoform1(h) <==> TFIIF-beta(h):AR-isoform1(h) (binding) | NCOR1(h) + AR-isoform1(h) <==> NCOR1(h):AR-isoform1(h) (binding) | AR-isoform1(h) + sumo1(h) --PIAS2(r)--> AR-isoform1(h){sumo} (sumoylation) | AR-isoform1(h) + sumo1(h) --PIAS1(m.s.)--> AR-isoform1(h){sumo} (sumoylation) | AR-isoform1(h) + sumo1(h) --PIAS2(r)--> AR-isoform1(h){sumo} (sumoylation) | AR-isoform1(h) + sumo1(h) --PIAS1(m.s.)--> AR-isoform1(h){sumo} (sumoylation) | AR-isoform1(h) --> TAT(r) (transactivation) | Egr-1(h) + AR-isoform1(h) <==> Egr-1(h):AR-isoform1(h) (binding) | Sp1(m.s.) + AR-isoform1(h) <==> Sp1(m.s.):AR-isoform1(h) (binding) | Egr-1(m.s.) + AR-isoform1(h) <==> Egr-1(m.s.):AR-isoform1(h) (binding) | AR-isoform1(h) + acetyl-CoA --p300(m.s.)--> AR-isoform1(h){ace} + CoA (acetylation) | AR-isoform1(h) + acetyl-CoA --> AR-isoform1(h){aceK} + CoA (acetylation) | p300(m.s.) + AR-isoform1(h) <==> p300(m.s.):AR-isoform1(h) (binding) | HDAC1(h) + AR-isoform1(h) <==> HDAC1(h):AR-isoform1(h) (binding) | NCOR1(m.s.) + AR-isoform1(h) <==> NCOR1(m.s.):AR-isoform1(h) (binding) | Smad3(h) + AR-isoform1(h) <==> Smad3(h):AR-isoform1(h) (binding) | AR-isoform1(h) --> CCND1(h) (transactivation) | AR-isoform1(h) --> cyclinD1(h) (increase of abundance) | AR-isoform1(h) --> cyclinE1(h) (increase of abundance) | sumo3(m.s.) + AR-isoform1(h) <==> sumo3(m.s.):AR-isoform1(h) (binding) | AR-isoform1(h) + acetyl-CoA --Tip60(h)--> AR-isoform1(h){ace} + CoA (acetylation) | HDAC1(h) + AR-isoform1(h) <==> HDAC1(h):AR-isoform1(h) (binding) | HDAC1(m.s.) + AR-isoform1(h) <==> HDAC1(m.s.):AR-isoform1(h) (binding) | AR-isoform1(h) + 7 ATP --> AR-isoform1(h){pS16}{pS81}{pS94}{pS256}{pS308}{pS424}{pS650} + 7 ADP (phosphorylation) | SIRT1(h) + AR-isoform1(h) <==> SIRT1(h):AR-isoform1(h) (binding) | STAT3(m.s.) + AR-isoform1(h) <==> STAT3(m.s.):AR-isoform1(h) (binding) | Hip-1(h) + AR-isoform1(h) <==> Hip-1(h):AR-isoform1(h) (binding) | AR-isoform1(h) + ATP --Cdk1(m.s.)--> AR-isoform1(h){pS81} + ADP (phosphorylation) | MNAR(m.s.) + AR-isoform1(h) <==> MNAR(m.s.):AR-isoform1(h) (binding) | AR-isoform1(h) + SM22(h) <==> AR-isoform1(h):SM22(h) (binding) | RIP140(h) + AR-isoform1(h) <==> RIP140(h):AR-isoform1(h) (binding) | DRIP205(h) + AR-isoform1(h) <==> DRIP205(h):AR-isoform1(h) (binding) | DRIP100(h) + AR-isoform1(h) <==> DRIP100(h):AR-isoform1(h) (binding) | TRAP170(h) + AR-isoform1(h) <==> TRAP170(h):AR-isoform1(h) (binding) | TRAP230(h) + AR-isoform1(h) <==> TRAP230(h):AR-isoform1(h) (binding) | TGIF-isoform2(h) + AR-isoform1(h) <==> TGIF-isoform2(h):AR-isoform1(h) (binding) | Hey1(m.s.) + AR-isoform1(h) <==> Hey1(m.s.):AR-isoform1(h) (binding) | beta-actin(h) + AR-isoform1(h) <==> beta-actin(h):AR-isoform1(h) (binding) | Hsp90(h) + AR-isoform1(h) <==> Hsp90(h):AR-isoform1(h) (binding) | prmt2(h) + AR-isoform1(h) <==> prmt2(h):AR-isoform1(h) (binding) | prmt2(h) + AR-isoform1(h) <==> prmt2(h):AR-isoform1(h) (binding) | SHP(m.s.) + AR-isoform1(h) <==> SHP(m.s.):AR-isoform1(h) (binding) | JMJD2A(m.s.) + AR-isoform1(h) <==> JMJD2A(m.s.):AR-isoform1(h) (binding) | JHDM3D(h) + AR-isoform1(h) <==> AR-isoform1(h):JHDM3D(h) (binding) | AR-isoform1(h) + PAK6(h) <==> AR-isoform1(h):PAK6(h) (binding) | AR-isoform1(h) + PAK6(h) <==> AR-isoform1(h):PAK6(h) (binding) | AR-isoform1(h) + 2 ATP --ACK-1(m.s.)--> AR-isoform1(h){pY267}{pY363} + 2 ADP (phosphorylation) | TIF2(h) + AR-isoform1(h) <==> TIF2(h):AR-isoform1(h) (binding) | AR-isoform1(h) + brca1(m.s.) <==> AR-isoform1(h):brca1(m.s.) (binding) | AR-isoform1(h) --> LCP1(h) (transactivation) | AR-isoform1(h) --TACE(h)--> AR-isoform1-p20(h) + protein remnants (cleavage) | AR-isoform1(h) --TACE(h)--> AR-isoform1-p17(h) + protein remnants (cleavage) | AR-isoform1(h) --TACE(h)--> AR-isoform1-p12(h) + protein remnants (cleavage) | AR-isoform1(h) + 2 ATP --> AR-isoform1(h){pS515}{pS578} + 2 ADP (phosphorylation) | AR-isoform1(h) + ATP --PKC(m.s.)--> AR-isoform1(h){pS578} + ADP (phosphorylation) | AR-isoform1(h) + Ku80(mo) <==> AR-isoform1(h):Ku80(mo) (binding) | AR-isoform1(h) + Ku70(mo) <==> AR-isoform1(h):Ku70(mo) (binding) | TIF2(m.s.) + AR-isoform1(h) <==> TIF2(m.s.):AR-isoform1(h) (binding) | AR-isoform1(h) + testosterone <==> AR-isoform1(h):testosterone (binding) | AR-isoform1(h) + 5alphaDHT <==> AR-isoform1(h):5alphaDHT (binding) | AR(h) --> AR-isoform1(h) (expression). | AR-isoform1(h) --> AR-isoform1(h) (translocation) | Abl-xbb1(m) --> AR-isoform1(h) (increase of abundance) | AR-isoform1(h) --> AR-isoform1(h) (translocation) | AR-isoform1(h) --> AR-isoform1(h) (translocation) | AR-isoform1(h) --> AR-isoform1(h) (translocation) | AR-isoform1(h){aceK630}{aceK632}{aceK633} --SIRT1(m)--> AR-isoform1(h) + 3 acetyl (deacetylation) | AR-isoform1(h){aceK630}{aceK632}{aceK633} --SIRT1(h)--> AR-isoform1(h) + 3 acetyl (deacetylation) | EGF(m.s.) --> AR-isoform1(h) (increase of abundance) | AR(h) --> AR-isoform2(h) (expression). |
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Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 386 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO). | Swiss-Prot 53.0 | 520 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO). | Swiss-Prot 53.0 | 650 | Phosphoserine | 12015328 | Phospho.ELM 6.0 | 424 | Phosphoserine | 12015328 | Phospho.ELM 6.0 | 81 | Phosphoserine | 12015328 | Phospho.ELM 6.0 | 16 | Phosphoserine | 12015328 | Phospho.ELM 6.0 | 308 | Phosphoserine | 12015328 | Phospho.ELM 6.0 | 256 | Phosphoserine | 12015328 | Phospho.ELM 6.0 | 94 | Phosphoserine | 15239671 | Phospho.ELM 6.0 | 515 | Phosphoserine | 15239671 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chrX |
Promoter: 66679099 - 66681099 | Agilent_014791 |
chrX |
Promoter: 66679099 - 66681099 | GoldenGate_Methylation_Cancer_Panel_I |
chrX |
Promoter: 66679099 - 66681099 | GSE27584 |
chrX |
Promoter: 66679099 - 66681099 | PMID:11880477 |
chrX |
Promoter: 66703908 - 66705908 | PMID:11880477 |
chrX |
Promoter: 66679099 - 66681099 | PMID:12845678 |
chrX |
Promoter: 66703908 - 66705908 | PMID:12845678 |
chrX |
Promoter: 66679099 - 66681099 | PMID:17192910 |
chrX |
Promoter: 66703908 - 66705908 | PMID:17192910 |
chrX |
Promoter: 66679099 - 66681099 | PMID:15328194 |
chrX |
Promoter: 66703908 - 66705908 | PMID:15328194 |
chrX |
Promoter: 66679099 - 66681099 | PMID:15367334 |
chrX |
Promoter: 66703908 - 66705908 | PMID:15367334 |